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Jesko Koehnke
Jesko Koehnke
Institute of Food and One Health, Leibniz Universität Hannover
Verified email at lci.uni-hannover.de - Homepage
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Year
New developments in RiPP discovery, enzymology and engineering
M Montalbán-López, TA Scott, S Ramesh, IR Rahman, AJ Van Heel, ...
Natural product reports 38 (1), 130-239, 2021
4742021
Structural analysis of leader peptide binding enables leader-free cyanobactin processing
J Koehnke, G Mann, AF Bent, H Ludewig, S Shirran, C Botting, T Lebl, ...
Nature chemical biology 11 (8), 558-563, 2015
1762015
The mechanism of patellamide macrocyclization revealed by the characterization of the PatG macrocyclase domain
J Koehnke, A Bent, WE Houssen, D Zollman, F Morawitz, S Shirran, ...
Nature structural & molecular biology 19 (8), 767, 2012
1522012
Splice form dependence of β-neurexin/neuroligin binding interactions
J Koehnke, PS Katsamba, G Ahlsen, F Bahna, J Vendome, B Honig, ...
Neuron 67 (1), 61-74, 2010
1122010
Ubc9 fusion–directed SUMOylation (UFDS): a method to analyze function of protein SUMOylation
A Jakobs, J Koehnke, F Himstedt, M Funk, B Korn, M Gaestel, ...
Nature methods 4 (3), 245-250, 2007
1032007
The cyanobactin heterocyclase enzyme: a processive adenylase that operates with a defined order of reaction
J Koehnke, AF Bent, D Zollman, K Smith, WE Houssen, X Zhu, G Mann, ...
Angewandte Chemie International Edition 52 (52), 13991-13996, 2013
982013
An efficient method for the in vitro production of azol (in) e‐based cyclic peptides
WE Houssen, AF Bent, AR McEwan, N Pieiller, J Tabudravu, J Koehnke, ...
Angewandte Chemie International Edition 53 (51), 14171-14174, 2014
712014
The natural product carolacton inhibits folate-dependent C1 metabolism by targeting FolD/MTHFD
C Fu, A Sikandar, J Donner, N Zaburannyi, J Herrmann, M Reck, ...
Nature communications 8 (1), 1529, 2017
702017
Thioholgamides: thioamide-containing cytotoxic RiPP natural products
L Kjaerulff, A Sikandar, N Zaburannyi, S Adam, J Herrmann, J Koehnke, ...
ACS Chemical Biology 12 (11), 2837-2841, 2017
682017
Crystal structure of the extracellular cholinesterase-like domain from neuroligin-2
J Koehnke, X Jin, EC Budreck, S Posy, P Scheiffele, B Honig, L Shapiro
Proceedings of the National Academy of Sciences 105 (6), 1873-1878, 2008
542008
In vitro reconstitution of α-pyrone ring formation in myxopyronin biosynthesis
H Sucipto, JH Sahner, E Prusov, SC Wenzel, RW Hartmann, J Koehnke, ...
Chemical Science 6 (8), 5076-5085, 2015
482015
Biosynthesis of Cittilins, Unusual Ribosomally Synthesized and Post-translationally Modified Peptides from Myxococcus xanthus
JJ Hug, J Dastbaz, S Adam, O Revermann, J Koehnke, D Krug, R Müller
ACS chemical biology 15 (8), 2221-2231, 2020
462020
The Discovery of New Cyanobactins from Cyanothece PCC 7425 Defines a New Signature for Processing of Patellamides
WE Houssen, J Koehnke, D Zollman, J Vendome, A Raab, MCM Smith, ...
ChemBioChem 13 (18), 2683-2689, 2012
462012
Crystal structures of β-neurexin 1 and β-neurexin 2 ectodomains and dynamics of splice insertion sequence 4
J Koehnke, X Jin, N Trbovic, PS Katsamba, J Brasch, G Ahlsen, ...
Structure 16 (3), 410-421, 2008
462008
The structural biology of patellamide biosynthesis
J Koehnke, AF Bent, WE Houssen, G Mann, M Jaspars, JH Naismith
Current opinion in structural biology 29, 112-121, 2014
452014
Binding Mode Characterization and Early in Vivo Evaluation of Fragment-Like Thiols as Inhibitors of the Virulence Factor LasB from Pseudomonas aeruginosa
AM Kany, A Sikandar, J Haupenthal, S Yahiaoui, CK Maurer, E Proschak, ...
ACS Infectious Diseases 4 (6), 988-997, 2018
422018
Structure and Biosynthesis of Crocagins: Polycyclic Posttranslationally Modified Ribosomal Peptides from Chondromyces crocatus
K Viehrig, F Surup, C Volz, J Herrmann, A Abou Fayad, S Adam, J Köhnke, ...
Angewandte Chemie International Edition 56 (26), 7407-7410, 2017
422017
N-Aryl-3-mercaptosuccinimides as Antivirulence Agents Targeting Pseudomonas aeruginosa Elastase and Clostridium Collagenases
J Konstantinović, S Yahiaoui, A Alhayek, J Haupenthal, E Schönauer, ...
Journal of Medicinal Chemistry 63 (15), 8359-8368, 2020
372020
Bottromycins-biosynthesis, synthesis and activity
L Franz, U Kazmaier, AW Truman, J Koehnke
Natural product reports 38 (9), 1659-1683, 2021
352021
Tutuilamides A–C: vinyl-chloride-containing cyclodepsipeptides from marine cyanobacteria with potent elastase inhibitory properties
L Keller, KM Canuto, C Liu, BM Suzuki, J Almaliti, A Sikandar, CB Naman, ...
ACS chemical biology 15 (3), 751-757, 2020
332020
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