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Mignon Loh
Mignon Loh
Professor of Pediatrics, UCSF
Adresse e-mail validée de ucsf.edu - Page d'accueil
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Molecular classification of cancer: class discovery and class prediction by gene expression monitoring
TR Golub, DK Slonim, P Tamayo, C Huard, M Gaasenbeek, JP Mesirov, ...
science 286 (5439), 531-537, 1999
155131999
The genetic basis of early T-cell precursor acute lymphoblastic leukaemia
J Zhang, L Ding, L Holmfeldt, G Wu, SL Heatley, D Payne-Turner, ...
Nature 481 (7380), 157-163, 2012
17802012
Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia
KG Roberts, Y Li, D Payne-Turner, RC Harvey, YL Yang, D Pei, ...
New England journal of medicine 371 (11), 1005-1015, 2014
14642014
Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia
AA Ferrando, DS Neuberg, J Staunton, ML Loh, C Huard, SC Raimondi, ...
Cancer cell 1 (1), 75-87, 2002
13022002
Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia
WJ Song, MG Sullivan, RD Legare, S Hutchings, X Tan, D Kufrin, ...
Nature genetics 23 (2), 166-175, 1999
12481999
International Consensus Classification of Myeloid Neoplasms and Acute Leukemias: integrating morphologic, clinical, and genomic data
DA Arber, A Orazi, RP Hasserjian, MJ Borowitz, KR Calvo, HM Kvasnicka, ...
Blood, The Journal of the American Society of Hematology 140 (11), 1200-1228, 2022
10202022
An oncogenic super-enhancer formed through somatic mutation of a noncoding intergenic element
MR Mansour, BJ Abraham, L Anders, A Berezovskaya, A Gutierrez, ...
Science 346 (6215), 1373-1377, 2014
8322014
Genetic alterations activating kinase and cytokine receptor signaling in high-risk acute lymphoblastic leukemia
KG Roberts, RD Morin, J Zhang, M Hirst, Y Zhao, X Su, SC Chen, ...
Cancer cell 22 (2), 153-166, 2012
8322012
The genomic landscape of pediatric and young adult T-lineage acute lymphoblastic leukemia
Y Liu, J Easton, Y Shao, J Maciaszek, Z Wang, MR Wilkinson, ...
Nature genetics 49 (8), 1211-1218, 2017
7942017
The genomic landscape of hypodiploid acute lymphoblastic leukemia
L Holmfeldt, L Wei, E Diaz-Flores, M Walsh, J Zhang, L Ding, ...
Nature genetics 45 (3), 242-252, 2013
7782013
JAK mutations in high-risk childhood acute lymphoblastic leukemia
CG Mullighan, J Zhang, RC Harvey, JR Collins-Underwood, ...
Proceedings of the National Academy of Sciences 106 (23), 9414-9418, 2009
7422009
Factors influencing survival after relapse from acute lymphoblastic leukemia: a Children's Oncology Group study
K Nguyen, M Devidas, SC Cheng, M La, EA Raetz, WL Carroll, NJ Winick, ...
Leukemia 22 (12), 2142-2150, 2008
6832008
Risk-and response-based classification of childhood B-precursor acute lymphoblastic leukemia: a combined analysis of prognostic markers from the Pediatric Oncology Group (POG …
KR Schultz, DJ Pullen, HN Sather, JJ Shuster, M Devidas, MJ Borowitz, ...
Blood 109 (3), 926-935, 2007
6042007
Activating mutations of the noonan syndrome-associated SHP2/PTPN11 gene in human solid tumors and adult acute myelogenous leukemia
M Bentires-Alj, JG Paez, FS David, H Keilhack, B Halmos, K Naoki, ...
Cancer research 64 (24), 8816-8820, 2004
6022004
The JAK2V617F activating mutation occurs in chronic myelomonocytic leukemia and acute myeloid leukemia, but not in acute lymphoblastic leukemia or chronic lymphocytic leukemia
RL Levine, M Loriaux, BJP Huntly, ML Loh, M Beran, E Stoffregen, ...
Blood 106 (10), 3377-3379, 2005
4952005
Mutations in PTPN11 implicate the SHP-2 phosphatase in leukemogenesis
ML Loh, S Vattikuti, S Schubbert, MG Reynolds, E Carlson, KH Lieuw, ...
Blood 103 (6), 2325-2331, 2004
4902004
PAX5-driven subtypes of B-progenitor acute lymphoblastic leukemia
Z Gu, ML Churchman, KG Roberts, I Moore, X Zhou, J Nakitandwe, ...
Nature genetics 51 (2), 296-307, 2019
4482019
Rise and fall of subclones from diagnosis to relapse in pediatric B-acute lymphoblastic leukaemia
X Ma, M Edmonson, D Yergeau, DM Muzny, OA Hampton, M Rusch, ...
Nature communications 6 (1), 6604, 2015
4462015
Germline CBL mutations cause developmental abnormalities and predispose to juvenile myelomonocytic leukemia
CM Niemeyer, MW Kang, DH Shin, I Furlan, M Erlacher, NJ Bunin, ...
Nature genetics 42 (9), 794-800, 2010
3952010
Stat5 is essential for the myelo-and lymphoproliferative disease induced by TEL/JAK2
J Schwaller, E Parganas, D Wang, D Cain, JC Aster, IR Williams, CK Lee, ...
Molecular cell 6 (3), 693-704, 2000
3762000
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