| ABCC6–mediated ATP secretion by the liver is the main source of the mineralization inhibitor inorganic pyrophosphate in the systemic circulation—brief report RS Jansen, S Duijst, S Mahakena, D Sommer, F Szeri, A Váradi, A Plomp, ... Arteriosclerosis, thrombosis, and vascular biology 34 (9), 1985-1989, 2014 | 277 | 2014 |
| ABCC6 prevents ectopic mineralization seen in pseudoxanthoma elasticum by inducing cellular nucleotide release RS Jansen, A Küçükosmanoğlu, M De Haas, S Sapthu, JA Otero, ... Proceedings of the National Academy of Sciences 110 (50), 20206-20211, 2013 | 240 | 2013 |
| Incorporation of concentration data below the limit of quantification in population pharmacokinetic analyses RJ Keizer, RS Jansen, H Rosing, B Thijssen, JH Beijnen, JHM Schellens, ... Pharmacology research & perspectives 3 (2), e00131, 2015 | 163 | 2015 |
| Pharmacogenetic screening of CYP3A and ABCB1 in relation to population pharmacokinetics of docetaxel TM Bosch, ADR Huitema, VD Doodeman, R Jansen, E Witteveen, ... Clinical cancer research 12 (19), 5786-5793, 2006 | 163 | 2006 |
| An exercise-inducible metabolite that suppresses feeding and obesity VL Li, Y He, K Contrepois, H Liu, JT Kim, AL Wiggenhorn, JT Tanzo, ... Nature 606 (7915), 785-790, 2022 | 129 | 2022 |
| Verapamil targets membrane energetics in Mycobacterium tuberculosis C Chen, S Gardete, RS Jansen, A Shetty, T Dick, KY Rhee, V Dartois Antimicrobial agents and chemotherapy 62 (5), 10.1128/aac. 02107-17, 2018 | 114 | 2018 |
| Multidrug resistance protein 2 is an important determinant of paclitaxel pharmacokinetics JS Lagas, ML Vlaming, O van Tellingen, E Wagenaar, RS Jansen, ... Clinical cancer research 12 (20), 6125-6132, 2006 | 113 | 2006 |
| LC-MS/MS systematic toxicological analysis: comparison of MS/MS spectra obtained with different instruments and settings R Jansen, G Lachatre, P Marquet Clinical biochemistry 38 (4), 362-372, 2005 | 107 | 2005 |
| Contribution of the drug transporter ABCG2 (breast cancer resistance protein) to resistance against anticancer nucleosides C De Wolf, R Jansen, H Yamaguchi, M De Haas, K Van De Wetering, ... Molecular cancer therapeutics 7 (9), 3092-3102, 2008 | 81 | 2008 |
| Coadministration of ritonavir strongly enhances the apparent oral bioavailability of docetaxel in patients with solid tumors RL Oostendorp, A Huitema, H Rosing, RS Jansen, R Ter Heine, ... Clinical Cancer Research 15 (12), 4228-4233, 2009 | 78 | 2009 |
| N-lactoyl-amino acids are ubiquitous metabolites that originate from CNDP2-mediated reverse proteolysis of lactate and amino acids RS Jansen, R Addie, R Merkx, A Fish, S Mahakena, OB Bleijerveld, ... Proceedings of the National Academy of Sciences 112 (21), 6601-6606, 2015 | 77 | 2015 |
| Oral administration of gemcitabine in patients with refractory tumors: a clinical and pharmacologic study SA Veltkamp, RS Jansen, S Callies, D Pluim, CM Visseren-Grul, H Rosing, ... Clinical cancer research 14 (11), 3477-3486, 2008 | 73 | 2008 |
| Quantitative analysis of gemcitabine triphosphate in human peripheral blood mononuclear cells using weak anion‐exchange liquid chromatography coupled with tandem mass spectrometry SA Veltkamp, MJX Hillebrand, H Rosing, RS Jansen, ER Wickremsinhe, ... Journal of mass spectrometry 41 (12), 1633-1642, 2006 | 65 | 2006 |
| ATP-binding cassette subfamily C member 5 (ABCC5) functions as an efflux transporter of glutamate conjugates and analogs RS Jansen, S Mahakena, M de Haas, P Borst, K van de Wetering Journal of Biological Chemistry 290 (51), 30429-30440, 2015 | 64 | 2015 |
| Dissociation of adaptive thermogenesis from glucose homeostasis in microbiome-deficient mice TI Krisko, HT Nicholls, CJ Bare, CD Holman, GG Putzel, RS Jansen, ... Cell Metabolism 31 (3), 592-604. e9, 2020 | 62 | 2020 |
| Fumarase deficiency causes protein and metabolite succination and intoxicates Mycobacterium tuberculosis N Ruecker, R Jansen, C Trujillo, S Puckett, P Jayachandran, GG Piroli, ... Cell chemical biology 24 (3), 306-315, 2017 | 58 | 2017 |
| Phase I study of Oral gemcitabine prodrug (LY2334737) alone and in combination with erlotinib in patients with advanced solid tumors SLW Koolen, PO Witteveen, RS Jansen, MHG Langenberg, ... Clinical cancer research 17 (18), 6071-6082, 2011 | 52 | 2011 |
| Retention studies of 2′-2′-difluorodeoxycytidine and 2′-2′-difluorodeoxyuridine nucleosides and nucleotides on porous graphitic carbon: Development of a liquid … RS Jansen, H Rosing, JHM Schellens, JH Beijnen Journal of chromatography A 1216 (15), 3168-3174, 2009 | 52 | 2009 |
| The membrane protein ANKH is crucial for bone mechanical performance by mediating cellular export of citrate and ATP F Szeri, S Lundkvist, S Donnelly, UFH Engelke, K Rhee, CJ Williams, ... PLoS genetics 16 (7), e1008884, 2020 | 50 | 2020 |
| Aspartate aminotransferase Rv3722c governs aspartate-dependent nitrogen metabolism in Mycobacterium tuberculosis RS Jansen, L Mandyoli, R Hughes, S Wakabayashi, JT Pinkham, ... Nature communications 11 (1), 1960, 2020 | 48 | 2020 |
Koen van de WeteringThomas Jefferson UniversityVerified email at jefferson.edu
