Maria E. Figueroa
Maria E. Figueroa
Professor in Biochemistry & Molecular Biology, Sylvester Comprehensive Cancer Center, University of
Verified email at - Homepage
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Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation
ME Figueroa, O Abdel-Wahab, C Lu, PS Ward, J Patel, A Shih, Y Li, ...
Cancer cell 18 (6), 553-567, 2010
Prognostic relevance of integrated genetic profiling in acute myeloid leukemia
JP Patel, M Gönen, ME Figueroa, H Fernandez, Z Sun, J Racevskis, ...
New England Journal of Medicine 366 (12), 1079-1089, 2012
IDH mutation impairs histone demethylation and results in a block to cell differentiation
C Lu, PS Ward, GS Kapoor, D Rohle, S Turcan, O Abdel-Wahab, ...
Nature 483 (7390), 474-478, 2012
methylKit: a comprehensive R package for the analysis of genome-wide DNA methylation profiles
A Akalin, M Kormaksson, S Li, FE Garrett-Bakelman, ME Figueroa, ...
Genome biology 13, 1-9, 2012
Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation
K Moran-Crusio, L Reavie, A Shih, O Abdel-Wahab, D Ndiaye-Lobry, ...
Cancer cell 20 (1), 11-24, 2011
Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells
JM Polo, S Liu, ME Figueroa, W Kulalert, S Eminli, KY Tan, E Apostolou, ...
Nature biotechnology 28 (8), 848-855, 2010
A molecular roadmap of reprogramming somatic cells into iPS cells
JM Polo, E Anderssen, RM Walsh, BA Schwarz, CM Nefzger, SM Lim, ...
Cell 151 (7), 1617-1632, 2012
DNA methylation signatures identify biologically distinct subtypes in acute myeloid leukemia
ME Figueroa, S Lugthart, Y Li, C Erpelinck-Verschueren, X Deng, ...
Cancer cell 17 (1), 13-27, 2010
Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis
L Busque, JP Patel, ME Figueroa, A Vasanthakumar, S Provost, ...
Nature genetics 44 (11), 1179-1181, 2012
Autophagy maintains the metabolism and function of young and old stem cells
TT Ho, MR Warr, ER Adelman, OM Lansinger, J Flach, EV Verovskaya, ...
Nature 543 (7644), 205-210, 2017
Restoration of TET2 function blocks aberrant self-renewal and leukemia progression
L Cimmino, I Dolgalev, Y Wang, A Yoshimi, GH Martin, J Wang, V Ng, ...
Cell 170 (6), 1079-1095. e20, 2017
IDH1 (R132H) mutation increases murine haematopoietic progenitors and alters epigenetics
M Sasaki, CB Knobbe, JC Munger, EF Lind, D Brenner, A Brüstle, ...
Nature 488 (7413), 656-659, 2012
DNMT1-interacting RNAs block gene-specific DNA methylation
A Di Ruscio, AK Ebralidze, T Benoukraf, G Amabile, LA Goff, J Terragni, ...
Nature 503 (7476), 371-376, 2013
Comparative isoschizomer profiling of cytosine methylation: the HELP assay
B Khulan, RF Thompson, K Ye, MJ Fazzari, M Suzuki, E Stasiek, ...
Genome research 16 (8), 1046-1055, 2006
MDS and secondary AML display unique patterns and abundance of aberrant DNA methylation
ME Figueroa, L Skrabanek, Y Li, A Jiemjit, TE Fandy, E Paietta, ...
Blood, The Journal of the American Society of Hematology 114 (16), 3448-3458, 2009
Base-pair resolution DNA methylation sequencing reveals profoundly divergent epigenetic landscapes in acute myeloid leukemia
A Akalin, FE Garrett-Bakelman, M Kormaksson, J Busuttil, L Zhang, ...
PLoS genetics 8 (6), e1002781, 2012
Mutant DNMT3A: a marker of poor prognosis in acute myeloid leukemia
AFT Ribeiro, M Pratcorona, C Erpelinck-Verschueren, V Rockova, ...
Blood, The Journal of the American Society of Hematology 119 (24), 5824-5831, 2012
DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia
R Rampal, A Alkalin, J Madzo, A Vasanthakumar, E Pronier, J Patel, Y Li, ...
Cell reports 9 (5), 1841-1855, 2014
HDAC4 promotes growth of colon cancer cells via repression of p21
AJ Wilson, DS Byun, S Nasser, LB Murray, K Ayyanar, D Arango, ...
Molecular biology of the cell 19 (10), 4062-4075, 2008
Prolonged administration of azacitidine with or without entinostat for myelodysplastic syndrome and acute myeloid leukemia with myelodysplasia-related changes: results of the …
T Prebet, Z Sun, ME Figueroa, R Ketterling, A Melnick, PL Greenberg, ...
Journal of Clinical Oncology 32 (12), 1242-1248, 2014
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