| Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation ME Figueroa, O Abdel-Wahab, C Lu, PS Ward, J Patel, A Shih, Y Li, ... Cancer cell 18 (6), 553-567, 2010 | 3166 | 2010 |
| Prognostic relevance of integrated genetic profiling in acute myeloid leukemia JP Patel, M Gönen, ME Figueroa, H Fernandez, Z Sun, J Racevskis, ... New England Journal of Medicine 366 (12), 1079-1089, 2012 | 2407 | 2012 |
| IDH mutation impairs histone demethylation and results in a block to cell differentiation C Lu, PS Ward, GS Kapoor, D Rohle, S Turcan, O Abdel-Wahab, ... Nature 483 (7390), 474-478, 2012 | 2215 | 2012 |
| methylKit: a comprehensive R package for the analysis of genome-wide DNA methylation profiles A Akalin, M Kormaksson, S Li, FE Garrett-Bakelman, ME Figueroa, ... Genome biology 13, 1-9, 2012 | 1926 | 2012 |
| Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation K Moran-Crusio, L Reavie, A Shih, O Abdel-Wahab, D Ndiaye-Lobry, ... Cancer cell 20 (1), 11-24, 2011 | 1502 | 2011 |
| Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells JM Polo, S Liu, ME Figueroa, W Kulalert, S Eminli, KY Tan, E Apostolou, ... Nature biotechnology 28 (8), 848-855, 2010 | 1425 | 2010 |
| A molecular roadmap of reprogramming somatic cells into iPS cells JM Polo, E Anderssen, RM Walsh, BA Schwarz, CM Nefzger, SM Lim, ... Cell 151 (7), 1617-1632, 2012 | 1016 | 2012 |
| DNA methylation signatures identify biologically distinct subtypes in acute myeloid leukemia ME Figueroa, S Lugthart, Y Li, C Erpelinck-Verschueren, X Deng, ... Cancer cell 17 (1), 13-27, 2010 | 999 | 2010 |
| Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis L Busque, JP Patel, ME Figueroa, A Vasanthakumar, S Provost, ... Nature genetics 44 (11), 1179-1181, 2012 | 913 | 2012 |
| Autophagy maintains the metabolism and function of young and old stem cells TT Ho, MR Warr, ER Adelman, OM Lansinger, J Flach, EV Verovskaya, ... Nature 543 (7644), 205-210, 2017 | 876 | 2017 |
| Restoration of TET2 function blocks aberrant self-renewal and leukemia progression L Cimmino, I Dolgalev, Y Wang, A Yoshimi, GH Martin, J Wang, V Ng, ... Cell 170 (6), 1079-1095. e20, 2017 | 685 | 2017 |
| IDH1 (R132H) mutation increases murine haematopoietic progenitors and alters epigenetics M Sasaki, CB Knobbe, JC Munger, EF Lind, D Brenner, A Brüstle, ... Nature 488 (7413), 656-659, 2012 | 621 | 2012 |
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| MDS and secondary AML display unique patterns and abundance of aberrant DNA methylation ME Figueroa, L Skrabanek, Y Li, A Jiemjit, TE Fandy, E Paietta, ... Blood, The Journal of the American Society of Hematology 114 (16), 3448-3458, 2009 | 408 | 2009 |
| Base-pair resolution DNA methylation sequencing reveals profoundly divergent epigenetic landscapes in acute myeloid leukemia A Akalin, FE Garrett-Bakelman, M Kormaksson, J Busuttil, L Zhang, ... PLoS genetics 8 (6), e1002781, 2012 | 339 | 2012 |
| Mutant DNMT3A: a marker of poor prognosis in acute myeloid leukemia AFT Ribeiro, M Pratcorona, C Erpelinck-Verschueren, V Rockova, ... Blood, The Journal of the American Society of Hematology 119 (24), 5824-5831, 2012 | 331 | 2012 |
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| Prolonged administration of azacitidine with or without entinostat for myelodysplastic syndrome and acute myeloid leukemia with myelodysplasia-related changes: results of the … T Prebet, Z Sun, ME Figueroa, R Ketterling, A Melnick, PL Greenberg, ... Journal of Clinical Oncology 32 (12), 1242-1248, 2014 | 259 | 2014 |
| HDAC4 promotes growth of colon cancer cells via repression of p21 AJ Wilson, DS Byun, S Nasser, LB Murray, K Ayyanar, D Arango, ... Molecular biology of the cell 19 (10), 4062-4075, 2008 | 257 | 2008 |
Francine E. Garrett-BakelmanAssistant Professor of Medicine and Biochemistry and Molecular Genetics, University of VirginiaVerified email at virginia.edu
