| Prevalence and architecture of de novo mutations in developmental disorders Nature 542 (7642), 433-438, 2017 | 878 | 2017 |
| Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression U Vősa, A Claringbould, HJ Westra, MJ Bonder, P Deelen, B Zeng, ... Nature genetics 53 (9), 1300-1310, 2021 | 702 | 2021 |
| Single-cell RNA sequencing identifies celltype-specific cis-eQTLs and co-expression QTLs MGP Van Der Wijst, H Brugge, DH De Vries, P Deelen, MA Swertz, ... Nature genetics 50 (4), 493-497, 2018 | 313 | 2018 |
| Histone lysine methylases and demethylases in the landscape of human developmental disorders V Faundes, WG Newman, L Bernardini, N Canham, J Clayton-Smith, ... The American Journal of Human Genetics 102 (1), 175-187, 2018 | 204 | 2018 |
| The single-cell eQTLGen consortium MGP van der Wijst, DH de Vries, HE Groot, G Trynka, CC Hon, MJ Bonder, ... elife 9, e52155, 2020 | 160 | 2020 |
| An integrative approach for building personalized gene regulatory networks for precision medicine MGP van der Wijst, DH de Vries, H Brugge, HJ Westra, L Franke Genome Medicine, 2018 | 83 | 2018 |
| Heterozygous variants in KMT2E cause a spectrum of neurodevelopmental disorders and epilepsy AH O’Donnell-Luria, LS Pais, V Faundes, JC Wood, A Sveden, V Luria, ... The American Journal of Human Genetics 104 (6), 1210-1222, 2019 | 65 | 2019 |
| Bi-allelic loss-of-function CACNA1B mutations in progressive epilepsy-dyskinesia KM Gorman, E Meyer, D Grozeva, E Spinelli, A McTague, A Sanchis-Juan, ... The American Journal of Human Genetics 104 (5), 948-956, 2019 | 58 | 2019 |
| Prevalence, phenotype and architecture of developmental disorders caused by de novo mutation: The Deciphering Developmental Disorders Study JF McRae, S Clayton, TW Fitzgerald, J Kaplanis, E Prigmore, D Rajan, ... BioRxiv, 049056, 2016 | 51 | 2016 |
| Deconvolution of bulk blood eQTL effects into immune cell subpopulations R Aguirre-Gamboa, N de Klein, J di Tommaso, A Claringbould, ... BMC bioinformatics 21, 1-23, 2020 | 47 | 2020 |
| Single-cell RNA-sequencing of peripheral blood mononuclear cells reveals widespread, context-specific gene expression regulation upon pathogenic exposure R Oelen, DH de Vries, H Brugge, MG Gordon, M Vochteloo, ... Nature communications 13 (1), 3267, 2022 | 36 | 2022 |
| Integrating GWAS with bulk and single-cell RNA-sequencing reveals a role for LY86 in the anti-Candida host response DH de Vries, V Matzaraki, OB Bakker, H Brugge, HJ Westra, MG Netea, ... PLoS pathogens 16 (4), e1008408, 2020 | 23 | 2020 |
| Lactobacillus reuteri Colonisation of Extremely Preterm Infants in a Randomised Placebo-Controlled Trial JE Spreckels, E Wejryd, G Marchini, B Jonsson, DH de Vries, ... Microorganisms 9 (5), 915, 2021 | 16 | 2021 |
| Identification of genetic variants that impact gene co-expression relationships using large-scale single-cell data S Li, KT Schmid, DH de Vries, M Korshevniuk, C Losert, R Oelen, ... Genome Biology 24 (1), 80, 2023 | 9 | 2023 |
| Life Lines Cohort S. et al.(2018) MGP van der Wijst, H Brugge, DH de Vries, P Deelen, MA Swertz Single-cell RNA sequencing identifies celltype-specific cis-eQTLs and co …, 0 | 9 | |
| Single-cell eQTLGen Consortium: a personalized understanding of disease MGP van der Wijst, DH de Vries, HE Groot, G Trynka, CC Hon, MC Nawijn, ... arXiv preprint arXiv:1909.12550, 2019 | 8 | 2019 |
| Single-cell RNA-sequencing reveals widespread personalized, context-specific gene expression regulation in immune cells R Oelen, DH de Vries, H Brugge, G Gordon, M Vochteloo, ... bioRxiv, 2021.06. 04.447088, 2021 | 6 | 2021 |
| The necessity of incorporating non-genetic risk factors into polygenic risk score models S van Dam, P Folkertsma, J Castela Forte, DH de Vries, ... Scientific Reports 13 (1), 1351, 2023 | 2 | 2023 |
| Single-cell RNA sequencing reveals cell-type specific cis-eQTLs in peripheral blood mononuclear cells MGP van der Wijst, H Brugge, DH de Vries, LH Franke bioRxiv, 177568, 2017 | 2 | 2017 |
| Effective questionnaire-based prediction models for type 2 diabetes across several ethnicities: a model development and validation study M Kokkorakis, P Folkertsma, S van Dam, N Sirotin, S Taheri, O Chagoury, ... EClinicalMedicine 64, 2023 | 1 | 2023 |
Lude FrankeProfessor of Functional Genomics, University Medical Centre GroningenVerified email at cleverfranke.com
