| Lipid clustering correlates with membrane curvature as revealed by molecular simulations of complex lipid bilayers H Koldsø, D Shorthouse, J Hélie, MSP Sansom PLoS computational biology 10 (10), e1003911, 2014 | 224 | 2014 |
| Tumor-induced stromal reprogramming drives lymph node transformation A Riedel, D Shorthouse, L Haas, BA Hall, J Shields Nature immunology 17 (9), 1118-1127, 2016 | 157 | 2016 |
| Nothing to sneeze at: a dynamic and integrative computational model of an influenza A virion T Reddy, D Shorthouse, DL Parton, E Jefferys, PW Fowler, M Chavent, ... Structure 23 (3), 584-597, 2015 | 108 | 2015 |
| Selection of oncogenic mutant clones in normal human skin varies with body site JC Fowler, C King, C Bryant, MWJ Hall, R Sood, SH Ong, E Earp, ... Cancer discovery 11 (2), 340-361, 2021 | 76 | 2021 |
| Lung tumors with distinct p53 mutations respond similarly to p53 targeted therapy but exhibit genotype-specific statin sensitivity FK Turrell, EM Kerr, M Gao, H Thorpe, GJ Doherty, J Cridge, ... Genes & development 31 (13), 1339-1353, 2017 | 63 | 2017 |
| Free energy landscape of lipid interactions with regulatory binding sites on the transmembrane domain of the EGF receptor G Hedger, D Shorthouse, H Koldsø, MSP Sansom The Journal of Physical Chemistry B 120 (33), 8154-8163, 2016 | 56 | 2016 |
| Molecular simulations of glycolipids: Towards mammalian cell membrane models D Shorthouse, G Hedger, H Koldsø, MSP Sansom Biochimie 120, 105-109, 2016 | 35 | 2016 |
| The NALCN channel regulates metastasis and nonmalignant cell dissemination EP Rahrmann, D Shorthouse, A Jassim, LP Hu, M Ortiz, B Mahler-Araujo, ... Nature genetics 54 (12), 1827-1838, 2022 | 32 | 2022 |
| Exploring the role of stromal osmoregulation in cancer and disease using executable modelling D Shorthouse, A Riedel, E Kerr, L Pedro, D Bihary, S Samarajiwa, ... Nature Communications 9 (1), 3011, 2018 | 21 | 2018 |
| Cancer-causing BRCA2 missense mutations disrupt an intracellular protein assembly mechanism to disable genome maintenance M Lee, D Shorthouse, R Mahen, BA Hall, AR Venkitaraman Nucleic Acids Research 49 (10), 5588-5604, 2021 | 20 | 2021 |
| SARS-CoV-2 variants are selecting for spike protein mutations that increase protein stability D Shorthouse, BA Hall Journal of Chemical Information and Modeling 61 (9), 4152-4155, 2021 | 13 | 2021 |
| Tumor-derived lactic acid modulates activation and metabolic status of draining lymph node stroma A Riedel, M Helal, L Pedro, JJ Swietlik, D Shorthouse, W Schmitz, L Haas, ... Cancer immunology research 10 (4), 482-497, 2022 | 12 | 2022 |
| Computational saturation screen reveals the landscape of mutations in human fumarate hydratase D Shorthouse, MWJ Hall, BA Hall Journal of Chemical Information and Modeling 61 (4), 1970-1980, 2021 | 11 | 2021 |
| Heterogeneity of the cancer cell line metabolic landscape D Shorthouse, J Bradley, SE Critchlow, C Bendtsen, BA Hall Molecular Systems Biology 18 (11), e11006, 2022 | 8 | 2022 |
| A toolbox for discrete modelling of cell signalling dynamics YZ Paterson, D Shorthouse, MW Pleijzier, N Piterman, C Bendtsen, ... Integrative Biology 10 (6), 370-382, 2018 | 8 | 2018 |
| HOXA9 has the hallmarks of a biological switch with implications in blood cancers L Talarmain, MA Clarke, D Shorthouse, L Cabrera-Cosme, DG Kent, ... Nature Communications 13 (1), 5829, 2022 | 7 | 2022 |
| Hé lie, J., and Sansom, MSP (2014). Lipid clustering correlates with membrane curvature as revealed by molecular simulations of complex lipid bilayers H Koldsø, D Shorthouse PLoS Comput. Biol 10, e1003911, 0 | 6 | |
| Mutations observed in somatic evolution reveal underlying gene mechanisms MWJ Hall, D Shorthouse, R Alcraft, PH Jones, BA Hall Communications Biology 6 (1), 753, 2023 | 4 | 2023 |
| Investigating structure function relationships in the NOTCH family through large-scale somatic DNA sequencing studies MWJ Hall, D Shorthouse, PH Jones, BA Hall bioRxiv, 2020.03. 31.018325, 2020 | 2 | 2020 |
| The Role of Potassium Channels in the Pathogenesis of Gastrointestinal Cancers and Therapeutic Potential D Shorthouse, JL Zhuang, EP Rahrmann, C Kosmidou, KW Rahrmann, ... | 2 | 2020 |
Benjamin A HallRoyal Society URF, UCLVerified email at ucl.ac.uk
