| Cyclooxygenase in biology and disease RN Dubois, SB Abramson, L Crofford, RA Gupta, LS Simon, ... The FASEB journal 12 (12), 1063-1073, 1998 | 3427 | 1998 |
| Cyclooxygenase regulates angiogenesis induced by colon cancer cells M Tsujii, S Kawano, S Tsuji, H Sawaoka, M Hori, RN DuBois cell 93 (5), 705-716, 1998 | 3341 | 1998 |
| Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas CE Eberhart, RJ Coffey, A Radhika, FM Giardiello, S Ferrenbach, ... Gastroenterology 107 (4), 1183-1188, 1994 | 3302 | 1994 |
| The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis G Steinbach, PM Lynch, RKS Phillips, MH Wallace, E Hawk, GB Gordon, ... New England Journal of Medicine 342 (26), 1946-1952, 2000 | 3241 | 2000 |
| Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2 M Tsujii, RN DuBois Cell 83 (3), 493-501, 1995 | 3104 | 1995 |
| Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK–STAT signaling pathway MA Meraz, JM White, KCF Sheehan, EA Bach, SJ Rodig, AS Dighe, ... Cell 84 (3), 431-442, 1996 | 2063 | 1996 |
| Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential M Tsujii, S Kawano, RN DuBois Proceedings of the National Academy of Sciences 94 (7), 3336-3340, 1997 | 1953 | 1997 |
| Eicosanoids and cancer D Wang, RN DuBois Nature Reviews Cancer 10 (3), 181-193, 2010 | 1943 | 2010 |
| The role of cyclooxygenases in inflammation, cancer, and development CS Williams, M Mann, RN DuBois Oncogene 18 (55), 7908-7916, 1999 | 1895 | 1999 |
| Modulation of Apoptosis and Bcl-2 Expression by Prostaglandin E2 in Human Colon Cancer Cells H Sheng, J Shao, JD Morrow, RD Beauchamp, RN DuBois Cancer research 58 (2), 362-366, 1998 | 1649 | 1998 |
| Colorectal cancer prevention and treatment by inhibition of cyclooxygenase-2 RA Gupta, RN DuBois Nature Reviews Cancer 1 (1), 11-21, 2001 | 1377 | 2001 |
| AACR Project GENIE: powering precision medicine through an international consortium AACR Project Genie Consortium, AACR Project GENIE Consortium, ... Cancer discovery 7 (8), 818-831, 2017 | 1234 | 2017 |
| Prostaglandins and cancer D Wang, RN DuBois Gut 55 (1), 115-122, 2006 | 1122 | 2006 |
| Cyclooxygenase-2 is associated with the macula densa of rat kidney and increases with salt restriction. RC Harris, JA McKanna, Y Akai, HR Jacobson, RN Dubois, MD Breyer The Journal of clinical investigation 94 (6), 2504-2510, 1994 | 1107 | 1994 |
| Host cyclooxygenase-2 modulates carcinoma growth CS Williams, M Tsujii, J Reese, SK Dey, RN DuBois The Journal of clinical investigation 105 (11), 1589-1594, 2000 | 986 | 2000 |
| Inhibition of human colon cancer cell growth by selective inhibition of cyclooxygenase-2. H Sheng, J Shao, SC Kirkland, P Isakson, RJ Coffey, J Morrow, ... The Journal of clinical investigation 99 (9), 2254-2259, 1997 | 974 | 1997 |
| The role of COX-2 in intestinal inflammation and colorectal cancer D Wang, RN DuBois Oncogene 29 (6), 781-788, 2010 | 932 | 2010 |
| Cyclooxygenase-2: a therapeutic target ME Turini, RN DuBois Annual review of medicine 53 (1), 35-57, 2002 | 911 | 2002 |
| Hypoxia induces cyclooxygenase-2 via the NF-κB p65 transcription factor in human vascular endothelial cells JF Schmedtje, YS Ji, WL Liu, RN DuBois, MS Runge Journal of Biological Chemistry 272 (1), 601-608, 1997 | 859 | 1997 |
| Prostaglandin E2 increases growth and motility of colorectal carcinoma cells H Sheng, J Shao, MK Washington, RN DuBois Journal of Biological Chemistry 276 (21), 18075-18081, 2001 | 822 | 2001 |
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