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| The JAK-STAT pathway: impact on human disease and therapeutic intervention JJ O'Shea, DM Schwartz, AV Villarino, M Gadina, IB McInnes, A Laurence Annual review of medicine 66 (1), 311-328, 2015 | 1556 | 2015 |
| Cytokine signaling in 2002: new surprises in the Jak/Stat pathway JJ O'Shea, M Gadina, RD Schreiber Cell 109 (2), S121-S131, 2002 | 1506 | 2002 |
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| Somatic Mutations in UBA1 and Severe Adult-Onset Autoinflammatory Disease DB Beck, MA Ferrada, KA Sikora, AK Ombrello, JC Collins, W Pei, ... New England Journal of Medicine 383 (27), 2628-2638, 2020 | 863 | 2020 |
| Early-onset stroke and vasculopathy associated with mutations in ADA2 Q Zhou, D Yang, AK Ombrello, AV Zavialov, C Toro, AV Zavialov, ... New England Journal of Medicine 370 (10), 911-920, 2014 | 853 | 2014 |
| Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behçet's disease EF Remmers, F Cosan, Y Kirino, MJ Ombrello, N Abaci, C Satorius, JM Le, ... Nature genetics 42 (8), 698-702, 2010 | 779 | 2010 |
| Modulation of innate and adaptive immune responses by tofacitinib (CP-690,550) K Ghoreschi, MI Jesson, X Li, JL Lee, S Ghosh, JW Alsup, JD Warner, ... The Journal of Immunology 186 (7), 4234-4243, 2011 | 723 | 2011 |
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| Cytokines and transcription factors that regulate T helper cell differentiation: new players and new insights D Agnello, CSR Lankford, J Bream, A Morinobu, M Gadina, JJ O'Shea, ... Journal of clinical immunology 23, 147-161, 2003 | 610 | 2003 |
| Loss-of-function mutations in TNFAIP3 leading to A20 haploinsufficiency cause an early-onset autoinflammatory disease Q Zhou, H Wang, DM Schwartz, M Stoffels, YH Park, Y Zhang, D Yang, ... Nature genetics 48 (1), 67-73, 2016 | 587 | 2016 |
| Fyn kinase initiates complementary signals required for IgE-dependent mast cell degranulation V Parravicini, M Gadina, M Kovarova, S Odom, C Gonzalez-Espinosa, ... Nature immunology 3 (8), 741-748, 2002 | 563 | 2002 |
| JAK1/2 inhibition with baricitinib in the treatment of autoinflammatory interferonopathies GAM Sanchez, A Reinhardt, S Ramsey, H Wittkowski, PJ Hashkes, ... The Journal of clinical investigation 128 (7), 3041-3052, 2018 | 494 | 2018 |
| Type 2 immunity in the skin and lungs CA Akdis, PD Arkwright, MC Brüggen, W Busse, M Gadina, ... Allergy 75 (7), 1582-1605, 2020 | 439 | 2020 |
| Super-enhancers delineate disease-associated regulatory nodes in T cells G Vahedi, Y Kanno, Y Furumoto, K Jiang, SCJ Parker, MR Erdos, ... Nature 520 (7548), 558-562, 2015 | 386 | 2015 |
John J. OSheaNational Institutes of HealthVerified email at mail.nih.gov
