Massimo Gadina
Massimo Gadina
Translational Immunology Section Office of Science and Technology, NIAMS, NIH
Verified email at - Homepage
Cited by
Cited by
Germline mutations in the extracellular domains of the 55 kDa TNF receptor, TNFR1, define a family of dominantly inherited autoinflammatory syndromes
MF McDermott, I Aksentijevich, J Galon, EM McDermott, BW Ogunkolade, ...
Cell 97 (1), 133-144, 1999
Cytokine signaling in 2002: new surprises in the Jak/Stat pathway
JJ O'Shea, M Gadina, RD Schreiber
Cell 109 (2), S121-S131, 2002
The JAK-STAT pathway: impact on human disease and therapeutic intervention
JJ O'Shea, DM Schwartz, AV Villarino, M Gadina, IB McInnes, A Laurence
Annual review of medicine 66, 311-328, 2015
Activated STING in a vascular and pulmonary syndrome
Y Liu, AA Jesus, B Marrero, D Yang, SE Ramsey, ...
New England Journal of Medicine 371 (6), 507-518, 2014
JAK inhibition as a therapeutic strategy for immune and inflammatory diseases
DM Schwartz, Y Kanno, A Villarino, M Ward, M Gadina, JJ O'Shea
Nature reviews Drug discovery 16 (12), 843-862, 2017
T-bet is rapidly induced by interferon-γ in lymphoid and myeloid cells
AA Lighvani, DM Frucht, D Jankovic, H Yamane, J Aliberti, BD Hissong, ...
Proceedings of the National Academy of Sciences 98 (26), 15137-15142, 2001
An autoinflammatory disease with deficiency of the interleukin-1–receptor antagonist
I Aksentijevich, SL Masters, PJ Ferguson, P Dancey, J Frenkel, ...
New England Journal of Medicine 360 (23), 2426-2437, 2009
JAK–STAT signaling as a target for inflammatory and autoimmune diseases: current and future prospects
S Banerjee, A Biehl, M Gadina, S Hasni, DM Schwartz
Drugs 77, 521-546, 2017
Early-onset stroke and vasculopathy associated with mutations in ADA2
Q Zhou, D Yang, AK Ombrello, AV Zavialov, C Toro, AV Zavialov, ...
New England Journal of Medicine 370 (10), 911-920, 2014
Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behçet's disease
EF Remmers, F Cosan, Y Kirino, MJ Ombrello, N Abaci, C Satorius, JM Le, ...
Nature genetics 42 (8), 698-702, 2010
Somatic Mutations in UBA1 and Severe Adult-Onset Autoinflammatory Disease
DB Beck, MA Ferrada, KA Sikora, AK Ombrello, JC Collins, W Pei, ...
New England Journal of Medicine 383 (27), 2628-2638, 2020
Modulation of innate and adaptive immune responses by tofacitinib (CP-690,550)
K Ghoreschi, MI Jesson, X Li, JL Lee, S Ghosh, JW Alsup, JD Warner, ...
The Journal of Immunology 186 (7), 4234-4243, 2011
Type I/II cytokines, JAKs, and new strategies for treating autoimmune diseases
DM Schwartz, M Bonelli, M Gadina, JJ O'shea
Nature Reviews Rheumatology 12 (1), 25-36, 2016
Critical role for STAT4 activation by type 1 interferons in the interferon-γ response to viral infection
KB Nguyen, WT Watford, R Salomon, SR Hofmann, GC Pien, A Morinobu, ...
Science 297 (5589), 2063-2066, 2002
Cytokines and transcription factors that regulate T helper cell differentiation: new players and new insights
D Agnello, CSR Lankford, J Bream, A Morinobu, M Gadina, JJ O'Shea, ...
Journal of clinical immunology 23, 147-161, 2003
Fyn kinase initiates complementary signals required for IgE-dependent mast cell degranulation
V Parravicini, M Gadina, M Kovarova, S Odom, C Gonzalez-Espinosa, ...
Nature immunology 3 (8), 741-748, 2002
Loss-of-function mutations in TNFAIP3 leading to A20 haploinsufficiency cause an early-onset autoinflammatory disease
Q Zhou, H Wang, DM Schwartz, M Stoffels, YH Park, Y Zhang, D Yang, ...
Nature genetics 48 (1), 67-73, 2016
JAK1/2 inhibition with baricitinib in the treatment of autoinflammatory interferonopathies
GAM Sanchez, A Reinhardt, S Ramsey, H Wittkowski, PJ Hashkes, ...
The Journal of clinical investigation 128 (7), 3041-3052, 2018
Type 2 immunity in the skin and lungs
CA Akdis, PD Arkwright, MC Brüggen, W Busse, M Gadina, ...
Allergy 75 (7), 1582-1605, 2020
Super-enhancers delineate disease-associated regulatory nodes in T cells
G Vahedi, Y Kanno, Y Furumoto, K Jiang, SCJ Parker, MR Erdos, ...
Nature 520 (7548), 558-562, 2015
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