Circulating exosomes induced by cardiac pressure overload contain functional angiotensin II type 1 receptors G Pironti, RT Strachan, D Abraham, S Mon-Wei Yu, M Chen, W Chen, ... Circulation 131 (24), 2120-2130, 2015 | 233 | 2015 |
Metabolomic analysis of pressure-overloaded and infarcted mouse hearts BE Sansbury, AM DeMartino, Z Xie, AC Brooks, RE Brainard, LJ Watson, ... Circulation: heart failure 7 (4), 634-642, 2014 | 226 | 2014 |
O-linked β-N-acetylglucosamine transferase is indispensable in the failing heart LJ Watson, HT Facundo, GA Ngoh, M Ameen, RE Brainard, KM Lemma, ... Proceedings of the National Academy of Sciences 107 (41), 17797-17802, 2010 | 200 | 2010 |
Augmented O-GlcNAc signaling attenuates oxidative stress and calcium overload in cardiomyocytes GA Ngoh, LJ Watson, HT Facundo, SP Jones Amino acids 40, 895-911, 2011 | 184 | 2011 |
Non-canonical glycosyltransferase modulates post-hypoxic cardiac myocyte death and mitochondrial permeability transition GA Ngoh, LJ Watson, HT Facundo, W Dillmann, SP Jones Journal of molecular and cellular cardiology 45 (2), 313-325, 2008 | 132 | 2008 |
O-GlcNAc signaling is essential for NFAT-mediated transcriptional reprogramming during cardiomyocyte hypertrophy HT Facundo, RE Brainard, LJ Watson, GA Ngoh, T Hamid, SD Prabhu, ... American Journal of Physiology-Heart and Circulatory Physiology 302 (10 …, 2012 | 115 | 2012 |
High fat feeding in mice is insufficient to induce cardiac dysfunction and does not exacerbate heart failure RE Brainard, LJ Watson, AM DeMartino, KR Brittian, RD Readnower, ... PloS one 8 (12), e83174, 2013 | 90 | 2013 |
Cardiomyocyte Ogt is essential for postnatal viability LJ Watson, BW Long, AM DeMartino, KR Brittian, RD Readnower, ... American Journal of Physiology-Heart and Circulatory Physiology 306 (1 …, 2014 | 85 | 2014 |
MicroRNA-539 is up-regulated in failing heart, and suppresses O-GlcNAcase expression S Muthusamy, AM DeMartino, LJ Watson, KR Brittian, A Zafir, ... Journal of Biological Chemistry 289 (43), 29665-29676, 2014 | 82 | 2014 |
The two-pore domain potassium channel TREK-1 mediates cardiac fibrosis and diastolic dysfunction DM Abraham, TE Lee, LJ Watson, L Mao, G Chandok, HG Wang, ... The Journal of clinical investigation 128 (11), 4843-4855, 2018 | 72 | 2018 |
Cardiac phosphatase-deficient 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase increases glycolysis, hypertrophy, and myocyte resistance to hypoxia Q Wang, RV Donthi, J Wang, AJ Lange, LJ Watson, SP Jones, PN Epstein American Journal of Physiology-Heart and Circulatory Physiology 294 (6 …, 2008 | 65 | 2008 |
Cardiac overexpression of 8-oxoguanine DNA glycosylase 1 protects mitochondrial DNA and reduces cardiac fibrosis following transaortic constriction J Wang, Q Wang, LJ Watson, SP Jones, PN Epstein American Journal of Physiology-Heart and Circulatory Physiology 301 (5 …, 2011 | 58 | 2011 |
Low-dose simvastatin improves survival and ventricular function via eNOS in congestive heart failure JJM Greer, AK Kakkar, JW Elrod, LJ Watson, SP Jones, DJ Lefer American Journal of Physiology-Heart and Circulatory Physiology 291 (6 …, 2006 | 53 | 2006 |
Cardiomyocyte Ogt limits ventricular dysfunction in mice following pressure overload without affecting hypertrophy S Dassanayaka, RE Brainard, LJ Watson, BW Long, KR Brittian, ... Basic research in cardiology 112, 1-17, 2017 | 43 | 2017 |
Reduced cardiac fructose 2, 6 bisphosphate increases hypertrophy and decreases glycolysis following aortic constriction J Wang, J Xu, Q Wang, RE Brainard, LJ Watson, SP Jones, PN Epstein PLoS One 8 (1), e53951, 2013 | 39 | 2013 |
Phosphorylation of Src by phosphoinositide 3-kinase regulates beta-adrenergic receptor-mediated EGFR transactivation LJ Watson, KM Alexander, ML Mohan, AL Bowman, S Mangmool, K Xiao, ... Cellular signalling 28 (10), 1580-1592, 2016 | 26 | 2016 |
The role of O-GlcNAc signaling during heart failure LJ Watson University of Louisville, 2011 | | 2011 |