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Karen Adelman
Karen Adelman
Harvard Medical School
Verified email at hms.harvard.edu - Homepage
Title
Cited by
Cited by
Year
Promoter-proximal pausing of RNA polymerase II: emerging roles in metazoans
K Adelman, JT Lis
Nature Reviews Genetics 13 (10), 720-731, 2012
13032012
RNA polymerase is poised for activation across the genome
GW Muse, DA Gilchrist, S Nechaev, R Shah, JS Parker, SF Grissom, ...
Nature genetics 39 (12), 1507-1511, 2007
8832007
RNA polymerase stalling at developmental control genes in the Drosophila melanogaster embryo
J Zeitlinger, A Stark, M Kellis, JW Hong, S Nechaev, K Adelman, M Levine, ...
Nature genetics 39 (12), 1512-1516, 2007
8762007
Global analysis of short RNAs reveals widespread promoter-proximal stalling and arrest of Pol II in Drosophila
S Nechaev, DC Fargo, G dos Santos, L Liu, Y Gao, K Adelman
Science 327 (5963), 335-338, 2010
4772010
Pausing of RNA polymerase II disrupts DNA-specified nucleosome organization to enable precise gene regulation
DA Gilchrist, G Dos Santos, DC Fargo, B Xie, Y Gao, L Li, K Adelman
Cell 143 (4), 540-551, 2010
4662010
CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1
B Bartkowiak, P Liu, HP Phatnani, NJ Fuda, JJ Cooper, DH Price, ...
Genes & development 24 (20), 2303-2316, 2010
4482010
Promoter-proximal pausing of RNA polymerase II: a nexus of gene regulation
L Core, K Adelman
Genes & development 33 (15-16), 960-982, 2019
4242019
Mll3 and Mll4 facilitate enhancer RNA synthesis and transcription from promoters independently of H3K4 monomethylation
KM Dorighi, T Swigut, T Henriques, NV Bhanu, BS Scruggs, N Nady, ...
Molecular cell 66 (4), 568-576. e4, 2017
3732017
Pol II waiting in the starting gates: Regulating the transition from transcription initiation into productive elongation
S Nechaev, K Adelman
Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1809 (1), 34-45, 2011
3422011
NELF-mediated stalling of Pol II can enhance gene expression by blocking promoter-proximal nucleosome assembly
DA Gilchrist, S Nechaev, C Lee, SKB Ghosh, JB Collins, L Li, DS Gilmour, ...
Genes & development 22 (14), 1921-1933, 2008
3382008
Widespread transcriptional pausing and elongation control at enhancers
T Henriques, BS Scruggs, MO Inouye, GW Muse, LH Williams, ...
Genes & development 32 (1), 26-41, 2018
3102018
Defining the status of RNA polymerase at promoters
LJ Core, JJ Waterfall, DA Gilchrist, DC Fargo, H Kwak, K Adelman, JT Lis
Cell reports 2 (4), 1025-1035, 2012
2712012
Stable pausing by RNA polymerase II provides an opportunity to target and integrate regulatory signals
T Henriques, DA Gilchrist, S Nechaev, M Bern, GW Muse, A Burkholder, ...
Molecular cell 52 (4), 517-528, 2013
2572013
Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq
JM Replogle, RA Saunders, AN Pogson, JA Hussmann, A Lenail, A Guna, ...
Cell 185 (14), 2559-2575. e28, 2022
2402022
Single molecule analysis of RNA polymerase elongation reveals uniform kinetic behavior
K Adelman, A La Porta, TJ Santangelo, JT Lis, JW Roberts, MD Wang
Proceedings of the National Academy of Sciences 99 (21), 13538-13543, 2002
2392002
Bidirectional transcription arises from two distinct hubs of transcription factor binding and active chromatin
BS Scruggs, DA Gilchrist, S Nechaev, GW Muse, A Burkholder, DC Fargo, ...
Molecular cell 58 (6), 1101-1112, 2015
2362015
PCIF1 catalyzes m6Am mRNA methylation to regulate gene expression
E Sendinc, D Valle-Garcia, A Dhall, H Chen, T Henriques, ...
Molecular cell 75 (3), 620-630. e9, 2019
2142019
Molecular mechanism of transcription inhibition by peptide antibiotic Microcin J25
K Adelman, J Yuzenkova, A La Porta, N Zenkin, J Lee, JT Lis, S Borukhov, ...
Molecular cell 14 (6), 753-762, 2004
1992004
Efficient release from promoter-proximal stall sites requires transcript cleavage factor TFIIS
K Adelman, MT Marr, J Werner, A Saunders, Z Ni, ED Andrulis, JT Lis
Molecular cell 17 (1), 103-112, 2005
1922005
Spt6 enhances the elongation rate of RNA polymerase II in vivo
MB Ardehali, J Yao, K Adelman, NJ Fuda, SJ Petesch, WW Webb, JT Lis
The EMBO journal 28 (8), 1067-1077, 2009
1862009
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