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| Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain M DiFiglia, E Sapp, KO Chase, SW Davies, GP Bates, JP Vonsattel, ... Science 277 (5334), 1990-1993, 1997 | 3371 | 1997 |
| Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation SW Davies, M Turmaine, BA Cozens, M DiFiglia, AH Sharp, CA Ross, ... Cell 90 (3), 537-548, 1997 | 2734 | 1997 |
| A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes ME MacDonald, CM Ambrose, MP Duyao, RH Myers, C Lin, L Srinidhi, ... Cell 72 (6), 971-983, 1993 | 2280 | 1993 |
| Huntington disease GP Bates, R Dorsey, JF Gusella, MR Hayden, C Kay, BR Leavitt, M Nance, ... Nature reviews Disease primers 1 (1), 1-21, 2015 | 1633 | 2015 |
| Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo E Scherzinger, R Lurz, M Turmaine, L Mangiarini, B Hollenbach, ... Cell 90 (3), 549-558, 1997 | 1604 | 1997 |
| The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription JS Steffan, A Kazantsev, O Spasic-Boskovic, M Greenwald, YZ Zhu, ... Proceedings of the National Academy of Sciences 97 (12), 6763-6768, 2000 | 1283 | 2000 |
| Characterization of progressive motor deficits in mice transgenic for the human Huntington’s disease mutation RJ Carter, LA Lione, T Humby, L Mangiarini, A Mahal, GP Bates, ... Journal of Neuroscience 19 (8), 3248-3257, 1999 | 1214 | 1999 |
| Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease E Hockly, VM Richon, B Woodman, DL Smith, X Zhou, E Rosa, ... Proceedings of the National Academy of Sciences 100 (4), 2041-2046, 2003 | 1063 | 2003 |
| Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: implications for Huntington’s disease pathology E Scherzinger, A Sittler, K Schweiger, V Heiser, R Lurz, R Hasenbank, ... Proceedings of the National Academy of Sciences 96 (8), 4604-4609, 1999 | 895 | 1999 |
| A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease M Björkqvist, EJ Wild, J Thiele, A Silvestroni, R Andre, N Lahiri, ... The Journal of experimental medicine 205 (8), 1869-1877, 2008 | 750 | 2008 |
| Huntington's disease G Bates, S Tabrizi, L Jones Oxford University Press, 2014 | 713 | 2014 |
| A novel gene encoding an integral membrane protein is mutated in nephropathic cystinosis M Town, G Jean, S Cherqui, M Attard, L Forestier, SA Whitmore, ... Nature genetics 18 (4), 319-324, 1998 | 704 | 1998 |
| Huntingtin aggregation and toxicity in Huntington's disease G Bates The Lancet 361 (9369), 1642-1644, 2003 | 668 | 2003 |
| Huntingtin and the molecular pathogenesis of Huntington's disease: Fourth in Molecular Medicine Review Series C Landles, GP Bates EMBO reports 5 (10), 958-963, 2004 | 638 | 2004 |
| Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human huntington disease gene JHJ Cha, CM Kosinski, JA Kerner, SA Alsdorf, L Mangiarini, SW Davies, ... Proceedings of the National Academy of Sciences 95 (11), 6480-6485, 1998 | 625 | 1998 |
| Global changes to the ubiquitin system in Huntington's disease EJ Bennett, TA Shaler, B Woodman, KY Ryu, TS Zaitseva, CH Becker, ... Nature 448 (7154), 704-708, 2007 | 607 | 2007 |
| Intranuclear neuronal inclusions in Huntington's disease and Dentatorubral and Pallidoluysian atrophy: correlation between the density of inclusions andIT15CAG triplet repeat … MW Becher, JA Kotzuk, AH Sharp, SW Davies, GP Bates, DL Price, ... Neurobiology of disease 4 (6), 387-397, 1998 | 572 | 1998 |
| Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease K Sathasivam, A Neueder, TA Gipson, C Landles, AC Benjamin, ... Proceedings of the National Academy of Sciences 110 (6), 2366-2370, 2013 | 549 | 2013 |
| Nonapoptotic neurodegeneration in a transgenic mouse model of Huntington's disease M Turmaine, A Raza, A Mahal, L Mangiarini, GP Bates, SW Davies Proceedings of the National Academy of Sciences 97 (14), 8093-8097, 2000 | 524 | 2000 |
