Interactive sites in the MyD88 Toll/interleukin (IL) 1 receptor domain responsible for coupling to the IL1β signaling pathway C Li, J Zienkiewicz, J Hawiger Journal of Biological Chemistry 280 (28), 26152-26159, 2005 | 138 | 2005 |
New paradigms in sepsis: from prevention to protection of failing microcirculation J Hawiger, RA Veach, J Zienkiewicz Journal of Thrombosis and Haemostasis 13 (10), 1743-1756, 2015 | 130 | 2015 |
Suppression of acute lung inflammation by intracellular peptide delivery of a nuclear import inhibitor D Liu, J Zienkiewicz, A DiGiandomenico, J Hawiger Molecular Therapy 17 (5), 796-802, 2009 | 83 | 2009 |
Decoding inflammation, its causes, genomic responses, and emerging countermeasures J Hawiger, J Zienkiewicz Scandinavian journal of immunology 90 (6), e12812, 2019 | 56 | 2019 |
Targeting nuclear import shuttles, importins/karyopherins alpha by a peptide mimicking the NF κB1/p50 nuclear localization sequence J Zienkiewicz, A Armitage, J Hawiger Journal of the American Heart Association 2 (5), e000386, 2013 | 46 | 2013 |
Experimental and theoretical studies of fused-ring persistent [1, 2, 4] thiadiazinyl radicals J Zienkiewicz, P Kaszynski, VG Young The Journal of Organic Chemistry 69 (22), 7525-7536, 2004 | 45 | 2004 |
In vivo islet protection by a nuclear import inhibitor in a mouse model of type 1 diabetes DJ Moore, J Zienkiewicz, PL Kendall, D Liu, X Liu, RA Veach, RD Collins, ... PLoS One 5 (10), e13235, 2010 | 41 | 2010 |
Fused-Ring Thiadiazines: Preparation and Crystallographic Characterization of 3-Phenyl Derivative of Benzo-, Pyridio[2,3-e]-, Pyrazino[2,3-e]-, and … J Zienkiewicz, P Kaszynski, VG Young The Journal of Organic Chemistry 69 (7), 2551-2561, 2004 | 31 | 2004 |
Nuclear transport modulation reduces hypercholesterolemia, atherosclerosis, and fatty liver Y Liu, AS Major, J Zienkiewicz, CL Gabriel, RA Veach, DJ Moore, ... Journal of the American Heart Association 2 (2), e000093, 2013 | 30 | 2013 |
Synthesis of Liquid Crystalline 4H-Benzo[1,2,4]thiadiazines and Generation of Persistent Radicals J Zienkiewicz, A Fryszkowska, K Zienkiewicz, F Guo, P Kaszynski, ... The Journal of Organic Chemistry 72 (9), 3510-3520, 2007 | 30 | 2007 |
Smectic polymorphism of the 4-butyl-4-alkoxyazobenzenes and 4-pentyl-4-alkoxyazobenzenes J Zienkiewicz, Z Galewski Liquid crystals 23 (1), 9-16, 1997 | 28 | 1997 |
The “genomic storm” induced by bacterial endotoxin is calmed by a nuclear transport modifier that attenuates localized and systemic inflammation A DiGiandomenico, RA Veach, J Zienkiewicz, DJ Moore, LS Wylezinski, ... PLoS One 9 (10), e110183, 2014 | 27 | 2014 |
Survival, bacterial clearance and thrombocytopenia are improved in polymicrobial sepsis by targeting nuclear transport shuttles RA Veach, Y Liu, J Zienkiewicz, LS Wylezinski, KL Boyd, JL Wynn, ... PLoS One 12 (6), e0179468, 2017 | 22 | 2017 |
Liquid crystalline properties of 4-hexyl-4'-alkoxyazobenzenes and 4-heptyl-4'-alkoxyazobenzenes J Zienkiewicz, Z Galewski Liquid Crystals: Chemistry and Structure 3319, 45-54, 1998 | 15 | 1998 |
Lethality in a murine model of pulmonary anthrax is reduced by combining nuclear transport modifier with antimicrobial therapy RA Veach, J Zienkiewicz, RD Collins, J Hawiger PLoS One 7 (1), e30527, 2012 | 13 | 2012 |
EGF receptor–mediated FUS phosphorylation promotes its nuclear translocation and fibrotic signaling M Chiusa, W Hu, J Zienkiewicz, X Chen, MZ Zhang, RC Harris, ... Journal of Cell Biology 219 (9), e202001120, 2020 | 12 | 2020 |
Compositions and methods for treating and preventing hyperlipidemia, fatty liver, atherosclerosis and other disorders associated with metabolic syndrome JJ Hawiger, RA Veach, J Zienkiewicz, Y Liu, RD Collins, A Major US Patent 9,044,433, 2015 | 12 | 2015 |
Hyperlipidemic hypersensitivity to lethal microbial inflammation and its reversal by selective targeting of nuclear transport shuttles Y Liu, J Zienkiewicz, KL Boyd, TE Smith, ZQ Xu, J Hawiger Scientific Reports 11 (1), 11907, 2021 | 9 | 2021 |
Liquid crystalline properties of 4-methyl-, 4-ethyl-and 4-propyl-4'-alkyloxyazobenzenes J Zienkiewicz Polish Journal of Chemistry 76 (2-3), 359-366, 2002 | 9 | 2002 |
Compositions and methods for preserving insulin-producing cells and insulin production and treating diabetes JJ Hawiger, RD Collins, DJ Moore, J Zienkiewicz, RA Veach US Patent 8,932,559, 2015 | 7 | 2015 |