Impact of genetic polymorphisms on human immune cell gene expression BJ Schmiedel, D Singh, A Madrigal, AG Valdovino-Gonzalez, BM White, ... Cell 175 (6), 1701-1715. e16, 2018 | 640 | 2018 |
Precursors of human CD4+ cytotoxic T lymphocytes identified by single-cell transcriptome analysis VS Patil, A Madrigal, BJ Schmiedel, J Clarke, P O’Rourke, AD de Silva, ... Science immunology 3 (19), eaan8664, 2018 | 236 | 2018 |
CD137 ligand mediates opposite effects in human and mouse NK cells and impairs NK-cell reactivity against human acute myeloid leukemia cells T Baessler, JE Charton, BJ Schmiedel, F Grünebach, M Krusch, A Wacker, ... Blood, The Journal of the American Society of Hematology 115 (15), 3058-3069, 2010 | 152 | 2010 |
Single-cell transcriptomic analysis of allergen-specific T cells in allergy and asthma G Seumois, C Ramírez-Suástegui, BJ Schmiedel, S Liang, B Peters, ... Science immunology 5 (48), eaba6087, 2020 | 127 | 2020 |
17q21 asthma-risk variants switch CTCF binding and regulate IL-2 production by T cells BJ Schmiedel, G Seumois, D Samaniego-Castruita, J Cayford, V Schulten, ... Nature communications 7 (1), 13426, 2016 | 111 | 2016 |
Glucocorticoid-induced tumor necrosis factor receptor–related protein ligand subverts immunosurveillance of acute myeloid leukemia in humans T Baessler, M Krusch, BJ Schmiedel, M Kloss, KM Baltz, A Wacker, ... Cancer research 69 (3), 1037-1045, 2009 | 102 | 2009 |
Azacytidine impairs NK cell reactivity while decitabine augments NK cell responsiveness toward stimulation BJ Schmiedel, V Arélin, F Gruenebach, M Krusch, SM Schmidt, HR Salih International journal of Cancer 128 (12), 2911-2922, 2011 | 91 | 2011 |
RANKL expression, function, and therapeutic targeting in multiple myeloma and chronic lymphocytic leukemia BJ Schmiedel, CA Scheible, T Nuebling, HG Kopp, S Wirths, M Azuma, ... Cancer research 73 (2), 683-694, 2013 | 79 | 2013 |
Promoter-interacting expression quantitative trait loci are enriched for functional genetic variants V Chandra, S Bhattacharyya, BJ Schmiedel, A Madrigal, ... Nature genetics 53 (1), 110-119, 2021 | 73 | 2021 |
4‐1BB ligand modulates direct and Rituximab‐induced NK‐cell reactivity in chronic lymphocytic leukemia C Buechele, T Baessler, BJ Schmiedel, CE Schumacher, ... European journal of immunology 42 (3), 737-748, 2012 | 66 | 2012 |
Glucocorticoid-induced TNFR-related protein (GITR) ligand modulates cytokine release and NK cell reactivity in chronic lymphocytic leukemia (CLL) C Buechele, T Baessler, S Wirths, JU Schmohl, BJ Schmiedel, HR Salih Leukemia 26 (5), 991-1000, 2012 | 64 | 2012 |
Neutralization of tumor-derived soluble glucocorticoid-induced TNFR-related protein ligand increases NK cell anti-tumor reactivity KM Baltz, M Krusch, T Baessler, BJ Schmiedel, A Bringmann, P Brossart, ... Blood, The Journal of the American Society of Hematology 112 (9), 3735-3743, 2008 | 63 | 2008 |
The immune checkpoint modulator OX40 and its ligand OX40L in NK-cell immunosurveillance and acute myeloid leukemia T Nuebling, CE Schumacher, M Hofmann, I Hagelstein, BJ Schmiedel, ... Cancer Immunology Research 6 (2), 209-221, 2018 | 58 | 2018 |
Reduced expression of phosphatase PTPN2 promotes pathogenic conversion of Tregs in autoimmunity MND Svensson, KM Doody, BJ Schmiedel, S Bhattacharyya, B Panwar, ... The Journal of Clinical Investigation 129 (3), 1193-1210, 2019 | 55 | 2019 |
Neutralization of (NK-cell-derived) B-cell activating factor by Belimumab restores sensitivity of chronic lymphoid leukemia cells to direct and Rituximab-induced NK lysis J Wild, BJ Schmiedel, A Maurer, S Raab, L Prokop, S Stevanović, D Dörfel, ... Leukemia 29 (8), 1676-1683, 2015 | 54 | 2015 |
Membrane‐associated phospholipase A1 beta (LIPI) is an Ewing tumour‐associated cancer/testis antigen JL Foell, M Hesse, I Volkmer, BJ Schmiedel, I Neumann, MS Staege Pediatric blood & cancer 51 (2), 228-234, 2008 | 53 | 2008 |
Fc-Optimized NKG2D–Fc constructs induce NK Cell antibody-dependent cellular cytotoxicity against breast cancer cells independently of HER2/neu expression status S Raab, J Steinbacher, BJ Schmiedel, PC Kousis, A Steinle, G Jung, ... The Journal of Immunology 193 (8), 4261-4272, 2014 | 47 | 2014 |
COVID-19 genetic risk variants are associated with expression of multiple genes in diverse immune cell types BJ Schmiedel, J Rocha, C Gonzalez-Colin, S Bhattacharyya, A Madrigal, ... Nature communications 12 (1), 6760, 2021 | 45 | 2021 |
An Fc‐optimized NKG2D‐immunoglobulin G fusion protein for induction of natural killer cell reactivity against leukemia J Steinbacher, K Baltz‐Ghahremanpour, BJ Schmiedel, A Steinle, G Jung, ... International journal of cancer 136 (5), 1073-1084, 2015 | 41 | 2015 |
Receptor activator for NF-κB ligand in acute myeloid leukemia: expression, function, and modulation of NK cell immunosurveillance BJ Schmiedel, T Nuebling, J Steinbacher, A Malinovska, CM Wende, ... The Journal of Immunology 190 (2), 821-831, 2013 | 38 | 2013 |