| Targeting DNA topoisomerase II in cancer chemotherapy JL Nitiss Nature Reviews Cancer 9 (5), 338-350, 2009 | 1970 | 2009 |
| DNA topoisomerase II and its growing repertoire of biological functions JL Nitiss Nature Reviews Cancer 9 (5), 327-337, 2009 | 935 | 2009 |
| Roles of eukaryotic topoisomerases in transcription, replication and genomic stability Y Pommier, Y Sun, SN Huang, JL Nitiss Nature reviews Molecular cell biology 17 (11), 703-721, 2016 | 846 | 2016 |
| DNA topoisomerase-targeting antitumor drugs can be studied in yeast. J Nitiss, JC Wang Proceedings of the National Academy of Sciences 85 (20), 7501-7505, 1988 | 633 | 1988 |
| Investigating the biological functions of DNA topoisomerases in eukaryotic cells JL Nitiss Biochimica et Biophysica Acta (BBA)-Gene Structure and Expression 1400 (1-3 …, 1998 | 470 | 1998 |
| Repair of topoisomerase I‐mediated DNA damage Y Pommier, JM Barcelo, VA Rao, O Sordet, AG Jobson, L Thibaut, ... Progress in nucleic acid research and molecular biology 81, 179-229, 2006 | 353 | 2006 |
| Biologically Active Carbazole Alkaloids from Murraya koenigii RS Ramsewak, MG Nair, GM Strasburg, DL DeWitt, JL Nitiss Journal of agricultural and food chemistry 47 (2), 444-447, 1999 | 286 | 1999 |
| Antitopoisomerase drug action and resistance JL Nitiss, WT Beck European Journal of Cancer 32 (6), 958-966, 1996 | 232 | 1996 |
| Amsacrine and etoposide hypersensitivity of yeast cells overexpressing DNA topoisomerase II JL Nitiss, YX Liu, P Harbury, M Jannatipour, R Wasserman, JC Wang Cancer research 52 (16), 4467-4472, 1992 | 187 | 1992 |
| Tyrosyl-DNA phosphodiesterase (Tdp1) participates in the repair of Top2-mediated DNA damage KC Nitiss, M Malik, X He, SW White, JL Nitiss Proceedings of the National Academy of Sciences 103 (24), 8953-8958, 2006 | 183 | 2006 |
| Mechanisms of cell killing by drugs that trap covalent complexes between DNA topoisomerases and DNA. JL Nitiss, JC Wang Molecular pharmacology 50 (5), 1095-1102, 1996 | 183 | 1996 |
| DNA topoisomerase II as a target for cancer chemotherapy JV Walker, JL Nitiss Cancer investigation 20 (4), 570-589, 2002 | 182 | 2002 |
| Cytotoxicity of quinolones toward eukaryotic cells. Identification of topoisomerase II as the primary cellular target for the quinolone CP-115,953 in yeast. SH Elsea, N Osheroff, JL Nitiss Journal of Biological Chemistry 267 (19), 13150-13153, 1992 | 166 | 1992 |
| Aberrant topoisomerase-1 DNA lesions are pathogenic in neurodegenerative genome instability syndromes S Katyal, Y Lee, KC Nitiss, SM Downing, Y Li, M Shimada, J Zhao, ... Nature neuroscience 17 (6), 813-821, 2014 | 157 | 2014 |
| Metabolites of daidzein and genistein and their biological activities YC Chang, MG Nair, JL Nitiss Journal of natural products 58 (12), 1901-1905, 1995 | 137 | 1995 |
| Topoisomerase assays JL Nitiss, E Soans, A Rogojina, A Seth, M Mishina Current protocols in pharmacology 57 (1), 3.3. 1-3.3. 27, 2012 | 134* | 2012 |
| Proteolytic Degradation of Topoisomerase II (Top2) Enables the Processing of Top2· DNA and Top2· RNA Covalent Complexes by Tyrosyl-DNA-Phosphodiesterase 2 (TDP2)*♦ R Gao, MJ Schellenberg, NH Shar-yin, M Abdelmalak, C Marchand, ... Journal of Biological Chemistry 289 (26), 17960-17969, 2014 | 133 | 2014 |
| Topoisomerase I-mediated Cytotoxicity of N-Methyl-N′-nitro-N-nitrosoguanidine: Trapping of Topoisomerase I by the O6-Methylguanine P Pourquier, JL Waltman, Y Urasaki, NA Loktionova, AE Pegg, JL Nitiss, ... Cancer research 61 (1), 53-58, 2001 | 127 | 2001 |
| A temperature sensitive topoisomerase II allele confers temperature dependent drug resistance on amsacrine and etoposide: a genetic system for determining the targets of … JL Nitiss, YX Liu, Y Hsiung Cancer Research 53 (1), 89-93, 1993 | 125 | 1993 |
| A novel mechanism of cell killing by anti-topoisomerase II bisdioxopiperazines LH Jensen, KC Nitiss, A Rose, J Dong, J Zhou, T Hu, N Osheroff, ... Journal of Biological Chemistry 275 (3), 2137-2146, 2000 | 113 | 2000 |
