Oliver Harschnitz
Oliver Harschnitz
Human Technopole
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A human pluripotent stem cell-based platform to study SARS-CoV-2 tropism and model virus infection in human cells and organoids
L Yang, Y Han, BE Nilsson-Payant, V Gupta, P Wang, X Duan, X Tang, ...
Cell stem cell 27 (1), 125-136. e7, 2020
Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis
W Van Rheenen, A Shatunov, AM Dekker, RL McLaughlin, FP Diekstra, ...
Nature genetics 48 (9), 1043-1048, 2016
Microglia innately develop within cerebral organoids
PR Ormel, R Vieira de Sá, EJ Van Bodegraven, H Karst, O Harschnitz, ...
Nature communications 9 (1), 4167, 2018
Fully defined human pluripotent stem cell-derived microglia and tri-culture system model C3 production in Alzheimer’s disease
SR Guttikonda, L Sikkema, J Tchieu, N Saurat, RM Walsh, O Harschnitz, ...
Nature neuroscience 24 (3), 343-354, 2021
Revising two-point discrimination assessment in normal aging and in patients with polyneuropathies
SI van Nes, CG Faber, RMTP Hamers, O Harschnitz, M Bakkers, ...
Journal of Neurology, Neurosurgery & Psychiatry 79 (7), 832-834, 2008
Human SNORA31 variations impair cortical neuron-intrinsic immunity to HSV-1 and underlie herpes simplex encephalitis
FG *Lafaille, O *Harschnitz, YS *Lee, P *Zhang, ML Hasek, G Kerner, ...
Nature Medicine 25 (12), 1873-1884, 2019
The neuroinvasiveness, neurotropism, and neurovirulence of SARS-CoV-2
L Bauer, BM Laksono, FMS de Vrij, SA Kushner, O Harschnitz, D van Riel
Trends in neurosciences, 2022
Human iPSC-derived trigeminal neurons lack constitutive TLR3-dependent immunity that protects cortical neurons from HSV-1 infection
B Zimmer, O Ewaleifoh, O Harschnitz, YS Lee, C Peneau, JL McAlpine, ...
Proceedings of the National Academy of Sciences 115 (37), E8775-E8782, 2018
TLR3 controls constitutive IFN-b antiviral immunity in human fibroblasts and cortical neurons
D Gao, MJ Ciancanelli*, P Zhang*, O Harschnitz*, V Bondet, M Hasek, ...
The Journal of Clinical Investigation, 2020
Autoantibody pathogenicity in a multifocal motor neuropathy induced pluripotent stem cell–derived model
O Harschnitz, LH van den Berg, LE Johansen, MD Jansen, S Kling, ...
Annals of Neurology 80 (1), 71-88, 2016
Whole blood transcriptome analysis in amyotrophic lateral sclerosis: A biomarker study
W Van Rheenen, FP Diekstra, O Harschnitz, HJ Westeneng, KR van Eijk, ...
PLoS One 13 (6), e0198874, 2018
Taking a risk: a therapeutic focus on ataxin-2 in amyotrophic lateral sclerosis?
DMA van den Heuvel, O Harschnitz, LH van den Berg, RJ Pasterkamp
Trends in Molecular Medicine 20 (1), 25-35, 2014
MMN: from immunological cross-talk to conduction block
O Harschnitz, BA Jongbloed, H Franssen, DCG Straver, WL van der Pol, ...
Journal of Clinical Immunology 34, 112-119, 2014
Human stem cell models to study host–virus interactions in the central nervous system
O Harschnitz, L Studer
Nature reviews Immunology 21 (7), 441-453, 2021
A comparative study of SMN protein and mRNA in blood and fibroblasts in patients with spinal muscular atrophy and healthy controls
RI Wadman, M Stam, MD Jansen, Y van der Weegen, CA Wijngaarde, ...
PloS one 11 (11), e0167087, 2016
Complement activity is associated with disease severity in multifocal motor neuropathy
L Vlam, EA Cats, O Harschnitz, MD Jansen, S Piepers, JH Veldink, ...
Neurology-Neuroimmunology Neuroinflammation 2 (4), 2015
SARS-CoV-2 infection causes dopaminergic neuron senescence
Y Han, L Yang, TW Kim, MS Nair, O Harschnitz, P Wang, J Zhu, SY Koo, ...
Research Square, 2021
Facial onset sensory and motor neuronopathy: new cases, cognitive changes, and pathophysiology
EMJ De Boer, AW Barritt, M Elamin, SJ Anderson, R Broad, A Nisbet, ...
Neurology: Clinical Practice 11 (2), 147-157, 2021
Intracranial application of free fasciocutaneous flaps in a novel sandwich technique for skull base reconstruction
RD Largo, DJ Schaefer, J Krueger, O Harschnitz, S Zimmerer, C Jaquiéry, ...
International journal of oral and maxillofacial surgery 40 (9), 931-937, 2011
Neuron-intrinsic immunity to viruses in mice and humans
SY Zhang, O Harschnitz, L Studer, JL Casanova
Current Opinion in Immunology 72, 309-317, 2021
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