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Holger Wille
Holger Wille
Professor of Biochemistry at the University of Alberta
Verified email at ualberta.ca - Homepage
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Cited by
Year
Eight prion strains have PrPSc molecules with different conformations
J Safar, H Wille, V Itri, D Groth, H Serban, M Torchia, FE Cohen, ...
Nature Medicine 4 (10), 1157-1165, 1998
15261998
Evidence for assembly of prions with left-handed β-helices into trimers
C Govaerts, H Wille, SB Prusiner, FE Cohen
Proceedings of the National Academy of Sciences of the United States of …, 2004
7212004
Subcellular colocalization of the cellular and scrapie prion proteins in caveolae-like membranous domains
M Vey, S Pilkuhn, H Wille, R Nixon, SJ DeArmond, EJ Smart, ...
Proceedings of the National Academy of Sciences 93 (25), 14945-14949, 1996
6961996
Alzheimer-like paired helical filaments and antiparallel dimers formed from microtubule-associated protein tau in vitro.
H Wille, G Drewes, J Biernat, EM Mandelkow, E Mandelkow
The Journal of cell biology 118 (3), 573-584, 1992
5911992
Structural studies of the scrapie prion protein by electron crystallography
H Wille, MD Michelitsch, V Guénebaut, S Supattapone, A Serban, ...
Proceedings of the National Academy of Sciences 99 (6), 3563-3568, 2002
5352002
Small-molecule aggregates inhibit amyloid polymerization
BY Feng, BH Toyama, H Wille, DW Colby, SR Collins, BCH May, ...
Nature chemical biology 4 (3), 197-199, 2008
3032008
Branched polyamines cure prion-infected neuroblastoma cells
S Supattapone, H Wille, L Uyechi, J Safar, P Tremblay, FC Szoka, ...
Journal of virology 75 (7), 3453-3461, 2001
2882001
Cytosolic prion protein in neurons
A Mironov Jr, D Latawiec, H Wille, E Bouzamondo-Bernstein, G Legname, ...
The Journal of neuroscience 23 (18), 7183-7193, 2003
2722003
Natural and synthetic prion structure from X-ray fiber diffraction
H Wille, W Bian, M McDonald, A Kendall, DW Colby, L Bloch, J Ollesch, ...
Proceedings of the National Academy of Sciences 106 (40), 16990-16995, 2009
2672009
Prion protein of 106 residues creates an artificial transmission barrier for prion replication in transgenic mice
S Supattapone, P Bosque, T Muramoto, H Wille, C Aagaard, D Peretz, ...
Cell 96 (6), 869-878, 1999
2661999
Conformational diversity of wild-type Tau fibrils specified by templated conformation change
B Frost, J Ollesch, H Wille, MI Diamond
Journal of Biological Chemistry 284 (6), 3546-3551, 2009
2612009
Design and construction of diverse mammalian prion strains
DW Colby, K Giles, G Legname, H Wille, IV Baskakov, SJ DeArmond, ...
Proceedings of the National Academy of Sciences 106 (48), 20417-20422, 2009
2492009
Tau protein becomes long and stiff upon phosphorylation: correlation between paracrystalline structure and degree of phosphorylation.
T Hagestedt, B Lichtenberg, H Wille, EM Mandelkow, E Mandelkow
The Journal of cell biology 109 (4), 1643-1651, 1989
2351989
α-Synuclein strains target distinct brain regions and cell types
A Lau, RWL So, HHC Lau, JC Sang, A Ruiz-Riquelme, SC Fleck, E Stuart, ...
Nature Neuroscience 23 (1), 21-31, 2020
2342020
Engineering a 2D protein–DNA crystal
J Malo, JC Mitchell, C Vénien‐Bryan, JR Harris, H Wille, DJ Sherratt, ...
Angewandte Chemie International Edition 44 (20), 3057-3061, 2005
2112005
THE CHICKEN NEURAL EXTRACELLULAR-MATRIX MOLECULE RESTRICTIN-SIMILARITY WITH EGF-LIKE, FIBRONECTIN TYPE-III-LIKE, AND FIBRINOGEN-LIKE MOTIFS
U NORENBERG, H WILLE, JM WOLFF, R FRANK, FG RATHJEN
NEURON 8 (5), 849-863, 1992
188*1992
Mechanisms of prion protein assembly into amyloid
J Stöhr, N Weinmann, H Wille, T Kaimann, L Nagel-Steger, E Birkmann, ...
Proceedings of the National Academy of Sciences 105 (7), 2409-2414, 2008
1732008
The structural architecture of an infectious mammalian prion using electron cryomicroscopy
E Vázquez-Fernández, MR Vos, P Afanasyev, L Cebey, AM Sevillano, ...
PLoS pathogens 12 (9), e1005835, 2016
1702016
A synthetic peptide initiates Gerstmann-Sträussler-Scheinker (GSS) disease in transgenic mice
K Kaneko, HL Ball, H Wille, H Zhang, D Groth, M Torchia, P Tremblay, ...
Journal of molecular biology 295 (4), 997-1007, 2000
1632000
Prion protein (PrP) synthetic peptides induce cellular PrP to acquire properties of the scrapie isoform
K Kaneko, D Peretz, KM Pan, TC Blochberger, H Wille, R Gabizon, ...
Proceedings of the National Academy of Sciences 92 (24), 11160-11164, 1995
1511995
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