Derivation of pluripotent epiblast stem cells from mammalian embryos IGM Brons, LE Smithers, MWB Trotter, P Rugg-Gunn, B Sun, ... Nature 448 (7150), 191-195, 2007 | 1697 | 2007 |
Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis M Takasato, XE Pei, HS Chiu, B Maier, GJ Baillie, C Ferguson, RG Parton, ... Nature 526, 564-568, 2015 | 728 | 2015 |
Dynamic equilibrium and heterogeneity of mouse pluripotent stem cells with distinct functional and epigenetic states K Hayashi, SMC de Sousa Lopes, F Tang, MA Surani Cell stem cell 3 (4), 391-401, 2008 | 630 | 2008 |
A reduction of mitochondrial DNA molecules during embryogenesis explains the rapid segregation of genotypes LM Cree, DC Samuels, SC de Sousa Lopes, HK Rajasimha, ... Nature genetics 40 (2), 249-254, 2008 | 443 | 2008 |
MicroRNA biogenesis is required for mouse primordial germ cell development and spermatogenesis K Hayashi, SMC de Sousa Lopes, M Kaneda, F Tang, P Hajkova, K Lao, ... PloS one 3 (3), e1738, 2008 | 409 | 2008 |
Germ cell specification in mice K Hayashi, SMC de Sousa Lopes, MA Surani Science 316 (5823), 394-396, 2007 | 311 | 2007 |
Transcriptional autoregulation of the bone related CBFA1/RUNX2 gene H Drissi, Q Luc, R Shakoori, S Chuva De Sousa Lopes, JY Choi, A Terry, ... Journal of cellular physiology 184 (3), 341-350, 2000 | 284 | 2000 |
BMP signaling mediated by ALK2 in the visceral endoderm is necessary for the generation of primordial germ cells in the mouse embryo SMC de Sousa Lopes, BAJ Roelen, RM Monteiro, R Emmens, HY Lin, ... Genes & development 18 (15), 1838-1849, 2004 | 217 | 2004 |
Atrial‐like cardiomyocytes from human pluripotent stem cells are a robust preclinical model for assessing atrial‐selective pharmacology HD Devalla, V Schwach, JW Ford, JT Milnes, S El‐Haou, C Jackson, ... EMBO molecular medicine 7 (4), 394-410, 2015 | 177 | 2015 |
Generation of stella‐GFP transgenic mice: A novel tool to study germ cell development B Payer, SM Chuva de Sousa Lopes, SC Barton, C Lee, M Saitou, ... Genesis 44 (2), 75-83, 2006 | 166 | 2006 |
Long-term expansion of functional mouse and human hepatocytes as 3D organoids H Hu, H Gehart, B Artegiani, C LÖpez-Iglesias, F Dekkers, O Basak, ... Cell 175 (6), 1591-1606. e19, 2018 | 150 | 2018 |
X chromosome activity in mouse XX primordial germ cells SMC de Sousa Lopes, K Hayashi, TC Shovlin, W Mifsud, MA Surani, ... PLoS Genet 4 (2), e30, 2008 | 132 | 2008 |
Tracking the progression of the human inner cell mass during embryonic stem cell derivation T O'Leary, B Heindryckx, S Lierman, D van Bruggen, JJ Goeman, ... Nature biotechnology 30 (3), 278-282, 2012 | 121 | 2012 |
Piwi Proteins and piRNAs in Mammalian Oocytes and Early Embryos EF Roovers, D Rosenkranz, M Mahdipour, CT Han, N He, ... Cell reports 10 (12), 2069-2082, 2015 | 112 | 2015 |
Alternative routes to induce naïve pluripotency in human embryonic stem cells G Duggal, S Warrier, S Ghimire, D Broekaert, M Van der Jeught, ... Stem Cells 33 (9), 2686-2698, 2015 | 107 | 2015 |
Spatio-temporal activation of Smad1 and Smad5 in vivo: monitoring transcriptional activity of Smad proteins RM Monteiro, SMC de Sousa Lopes, O Korchynskyi, P ten Dijke, ... Journal of cell science 117 (20), 4653-4663, 2004 | 92 | 2004 |
Transcriptome of human foetal heart compared with cardiomyocytes from pluripotent stem cells CW van den Berg, S Okawa, SMC de Sousa Lopes, L van Iperen, ... Development 142 (18), 3231-3238, 2015 | 87 | 2015 |
Connective tissue growth factor expression and Smad signaling during mouse heart development and myocardial infarction SM Chuva De Sousa Lopes, A Feijen, J Korving, O Korchynskyi, ... Developmental dynamics: an official publication of the American Association …, 2004 | 85 | 2004 |
Real time monitoring of BMP Smads transcriptional activity during mouse development RM Monteiro, SMC de Sousa Lopes, M Bialecka, S de Boer, A Zwijsen, ... Genesis 46 (7), 335-346, 2008 | 82 | 2008 |
KeyGenes, a tool to probe tissue differentiation using a human fetal transcriptional atlas MS Roost, L van Iperen, Y Ariyurek, HP Buermans, W Arindrarto, ... Stem cell reports 4 (6), 1112-1124, 2015 | 74 | 2015 |