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Dr Bhuvaneish. T.Selvaraj
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C9ORF72 repeat expansion causes vulnerability of motor neurons to Ca2+-permeable AMPA receptor-mediated excitotoxicity
BT Selvaraj, MR Livesey, C Zhao, JM Gregory, OT James, EM Cleary, ...
Nature communications 9 (1), 347, 2018
1872018
Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia
M Prudencio, J Humphrey, S Pickles, AL Brown, SE Hill, JM Kachergus, ...
The Journal of clinical investigation 130 (11), 2020
1292020
Mutant C9orf72 human iPSC‐derived astrocytes cause non‐cell autonomous motor neuron pathophysiology
C Zhao, AC Devlin, AK Chouhan, BT Selvaraj, M Stavrou, K Burr, V Brivio, ...
Glia 68 (5), 1046-1064, 2020
962020
Mitochondrial bioenergetic deficits in C9orf72 amyotrophic lateral sclerosis motor neurons cause dysfunctional axonal homeostasis
AR Mehta, JM Gregory, O Dando, RN Carter, K Burr, J Nanda, D Story, ...
Acta neuropathologica 141, 257-279, 2021
922021
Local axonal function of STAT3 rescues axon degeneration in the pmn model of motoneuron disease
BT Selvaraj, N Frank, FLP Bender, E Asan, M Sendtner
Journal of Cell Biology 199 (3), 437-451, 2012
902012
Maturation and electrophysiological properties of human pluripotent stem cell-derived oligodendrocytes
MR Livesey, D Magnani, EM Cleary, NA Vasistha, OT James, BT Selvaraj, ...
Stem cells 34 (4), 1040-1053, 2016
742016
C9orf72-derived arginine-containing dipeptide repeats associate with axonal transport machinery and impede microtubule-based motility
L Fumagalli, FL Young, S Boeynaems, M De Decker, AR Mehta, ...
Science Advances 7 (15), eabg3013, 2021
652021
Hypothermic preconditioning of human cortical neurons requires proteostatic priming
NM Rzechorzek, P Connick, R Patani, BT Selvaraj, S Chandran
EBioMedicine 2 (6), 528-535, 2015
522015
Dysregulation of AMPA receptor subunit expression in sporadic ALS post‐mortem brain
JM Gregory, MR Livesey, K McDade, BT Selvaraj, SK Barton, S Chandran, ...
The Journal of pathology 250 (1), 67-78, 2020
462020
iPSC-derived myelinoids to study myelin biology of humans
OG James, BT Selvaraj, D Magnani, K Burr, P Connick, SK Barton, ...
Developmental Cell 56 (9), 1346-1358. e6, 2021
412021
Altered network properties in C9ORF72 repeat expansion cortical neurons are due to synaptic dysfunction
EM Perkins, K Burr, P Banerjee, AR Mehta, O Dando, BT Selvaraj, ...
Molecular neurodegeneration 16, 1-16, 2021
392021
Evidence for evolutionary divergence of activity-dependent gene expression in developing neurons
J Qiu, J McQueen, B Bilican, O Dando, D Magnani, K Punovuori, ...
Elife 5, e20337, 2016
362016
Neurofilament depletion improves microtubule dynamics via modulation of Stat3/stathmin signaling
P Yadav, BT Selvaraj, FLP Bender, M Behringer, M Moradi, R Sivadasan, ...
Acta neuropathologica 132, 93-110, 2016
292016
Targeting mitochondrial dysfunction in amyotrophic lateral sclerosis: a systematic review and meta-analysis
AR Mehta, R Walters, FM Waldron, S Pal, BT Selvaraj, MR Macleod, ...
Brain communications 1 (1), fcz009, 2019
272019
FMRP interacts with C/D box snoRNA in the nucleus and regulates ribosomal RNA methylation
MN D'Souza, NKC Gowda, V Tiwari, RO Babu, P Anand, SG Dastidar, ...
IScience 9, 399-411, 2018
242018
CNTF, STAT3 and new therapies for axonal degeneration: what are they and what can they do?
BT Selvaraj, M Sendtner
Expert Review of Neurotherapeutics 13 (3), 239-241, 2013
202013
Familial t (1; 11) translocation is associated with disruption of white matter structural integrity and oligodendrocyte–myelin dysfunction
NA Vasistha, M Johnstone, SK Barton, SE Mayerl, B Thangaraj Selvaraj, ...
Molecular psychiatry 24 (11), 1641-1654, 2019
172019
Modeling the C9ORF72 repeat expansion mutation using human induced pluripotent stem cells
BT Selvaraj, MR Livesey, S Chandran
Brain Pathology 27 (4), 518-524, 2017
172017
Generation of twenty four induced pluripotent stem cell lines from twenty four members of the Lothian Birth Cohort 1936
J Toombs, L Panther, L Ornelas, C Liu, E Gomez, R Martín-Ibáñez, ...
Stem cell research 46, 101851, 2020
152020
Cell-autonomous immune dysfunction driven by disrupted autophagy in C9orf72-ALS iPSC-derived microglia contributes to neurodegeneration
P Banerjee, AR Mehta, RS Nirujogi, J Cooper, OG James, J Nanda, ...
Science Advances 9 (16), eabq0651, 2023
142023
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