| Long-term expansion of functional mouse and human hepatocytes as 3D organoids H Hu, H Gehart, B Artegiani, C LÖpez-Iglesias, F Dekkers, O Basak, ... Cell 175 (6), 1591-1606. e19, 2018 | 597 | 2018 |
| High-resolution 3D imaging of fixed and cleared organoids JF Dekkers, M Alieva, LM Wellens, HCR Ariese, PR Jamieson, AM Vonk, ... Nature protocols 14 (6), 1756-1771, 2019 | 367 | 2019 |
| Building consensus on definition and nomenclature of hepatic, pancreatic, and biliary organoids A Marsee, FJM Roos, MMA Verstegen, F Roos, M Verstegen, H Clevers, ... Cell Stem Cell 28 (5), 816-832, 2021 | 164 | 2021 |
| CRL4B catalyzes H2AK119 monoubiquitination and coordinates with PRC2 to promote tumorigenesis H Hu, Y Yang, Q Ji, W Zhao, B Jiang, R Liu, J Yuan, Q Liu, X Li, Y Zou, ... Cancer cell 22 (6), 781-795, 2012 | 159 | 2012 |
| Probing the tumor suppressor function of BAP1 in CRISPR-engineered human liver organoids B Artegiani, L van Voorthuijsen, RGH Lindeboom, D Seinstra, I Heo, ... Cell Stem Cell 24 (6), 927-943. e6, 2019 | 155 | 2019 |
| Chuva de Sousa Lopes, SM; Begthel, H.; Korving, J.; et al. Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids H Hu, H Gehart, B Artegiani, C LÖpez-Iglesias, F Dekkers, O Basak, ... Cell 175 (6), 1591-1606, 2018 | 150 | 2018 |
| A missense mutation in SLC33A1, which encodes the acetyl-CoA transporter, causes autosomal-dominant spastic paraplegia (SPG42) P Lin, J Li, Q Liu, F Mao, J Li, R Qiu, H Hu, Y Song, Y Yang, G Gao, C Yan, ... The American Journal of Human Genetics 83 (6), 752-759, 2008 | 143 | 2008 |
| MiR-135b-5p and MiR-499a-3p promote cell proliferation and migration in atherosclerosis by directly targeting MEF2C Z Xu, Y Han, J Liu, F Jiang, H Hu, Y Wang, Q Liu, Y Gong, X Li Scientific Reports 5 (1), 12276, 2015 | 104 | 2015 |
| CRL4B promotes tumorigenesis by coordinating with SUV39H1/HP1/DNMT3A in DNA methylation-based epigenetic silencing Y Yang, R Liu, R Qiu, Y Zheng, W Huang, H Hu, Q Ji, H He, Y Shang, ... Oncogene 34 (1), 104-118, 2015 | 100 | 2015 |
| Establishment of human fetal hepatocyte organoids and CRISPR–Cas9-based gene knockin and knockout in organoid cultures from human liver D Hendriks, B Artegiani, H Hu, S Chuva de Sousa Lopes, H Clevers Nature Protocols 16 (1), 182-217, 2021 | 79 | 2021 |
| CUL4B activates Wnt/β‐catenin signalling in hepatocellular carcinoma by repressing Wnt antagonists J Yuan, B Han, H Hu, Y Qian, Z Liu, Z Wei, X Liang, B Jiang, C Shao, ... The Journal of pathology 235 (5), 784-795, 2015 | 70 | 2015 |
| Chemokine receptor CXCR 2 is transactivated by p53 and induces p38‐mediated cellular senescence in response to DNA damage H Guo, Z Liu, B Xu, H Hu, Z Wei, Q Liu, X Zhang, X Ding, Y Wang, M Zhao, ... Aging Cell 12 (6), 1110-1121, 2013 | 56 | 2013 |
| A combined model of human iPSC‐derived liver organoids and hepatocytes reveals ferroptosis in DGUOK mutant mtDNA depletion syndrome J Guo, L Duan, X He, S Li, Y Wu, G Xiang, F Bao, L Yang, H Shi, M Gao, ... Advanced Science 8 (10), 2004680, 2021 | 52 | 2021 |
| Chuva de Sousa Lopes, S.; Clevers, H. Establishment of human fetal hepatocyte organoids and CRISPR-Cas9-based gene knockin and knockout in organoid cultures from human liver D Hendriks, B Artegiani, H Hu Nat. Protoc 16, 182-217, 2021 | 52 | 2021 |
| The CUL4B/AKT/β-catenin axis restricts the accumulation of myeloid-derived suppressor cells to prohibit the establishment of a tumor-permissive microenvironment Y Qian, J Yuan, H Hu, Q Yang, J Li, S Zhang, B Jiang, C Shao, Y Gong Cancer Research 75 (23), 5070-5083, 2015 | 44 | 2015 |
| CRL4B interacts with and coordinates the SIN3A-HDAC complex to repress CDKN1A and drive cell cycle progression Q Ji, H Hu, F Yang, J Yuan, Y Yang, L Jiang, Y Qian, B Jiang, Y Zou, ... Journal of Cell Science 127 (21), 4679-4691, 2014 | 42 | 2014 |
| In vitro grafting of hepatic spheroids and organoids on a microfluidic vascular bed F Bonanini, D Kurek, S Previdi, A Nicolas, D Hendriks, S de Ruiter, ... Angiogenesis 25 (4), 455-470, 2022 | 41 | 2022 |
| Dysregulation of the miR‐194–CUL 4B negative feedback loop drives tumorigenesis in non‐small‐cell lung carcinoma J Mi, Y Zou, X Lin, J Lu, X Liu, H Zhao, X Ye, H Hu, B Jiang, B Han, ... Molecular oncology 11 (3), 305-319, 2017 | 39 | 2017 |
| A cullin 4B-RING E3 ligase complex fine-tunes pancreatic δ cell paracrine interactions Q Li, M Cui, F Yang, N Li, B Jiang, Z Yu, D Zhang, Y Wang, X Zhu, H Hu, ... The Journal of Clinical Investigation 127 (7), 2631-2646, 2017 | 33 | 2017 |
| CUL4B promotes replication licensing by up-regulating the CDK2–CDC6 cascade Y Zou, J Mi, W Wang, J Lu, W Zhao, Z Liu, H Hu, Y Yang, X Gao, B Jiang, ... Journal of Cell Biology 200 (6), 743-756, 2013 | 30 | 2013 |
