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Yuen Yi C. Tam
Yuen Yi C. Tam
Integrated Nanotherapeutics Inc.
Geverifieerd e-mailadres voor mail.ubc.ca
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On the formation and morphology of lipid nanoparticles containing ionizable cationic lipids and siRNA
JA Kulkarni, MM Darjuan, JE Mercer, S Chen, R Van Der Meel, ...
ACS nano 12 (5), 4787-4795, 2018
3692018
Influence of polyethylene glycol lipid desorption rates on pharmacokinetics and pharmacodynamics of siRNA lipid nanoparticles
BL Mui, YK Tam, M Jayaraman, SM Ansell, X Du, YYC Tam, PJC Lin, ...
Molecular Therapy-Nucleic Acids 2, 2013
2932013
Interaction landscape of membrane-protein complexes in Saccharomyces cerevisiae
M Babu, J Vlasblom, S Pu, X Guo, C Graham, BDM Bean, HE Burston, ...
Nature 489 (7417), 585-589, 2012
2772012
Influence of particle size on the in vivo potency of lipid nanoparticle formulations of siRNA
S Chen, YYC Tam, PJC Lin, MMH Sung, YK Tam, PR Cullis
Journal of Controlled Release 235, 236-244, 2016
2672016
Microfluidic mixing: a general method for encapsulating macromolecules in lipid nanoparticle systems
AKK Leung, YYC Tam, S Chen, IM Hafez, PR Cullis
The Journal of Physical Chemistry B 119 (28), 8698-8706, 2015
2522015
Influence of cationic lipid composition on gene silencing properties of lipid nanoparticle formulations of siRNA in antigen-presenting cells
G Basha, TI Novobrantseva, N Rosin, YYC Tam, IM Hafez, MK Wong, ...
Molecular Therapy 19 (12), 2186-2200, 2011
2482011
Advances in lipid nanoparticles for siRNA delivery
YYC Tam, S Chen, PR Cullis
Pharmaceutics 5 (3), 498-507, 2013
2322013
On the role of helper lipids in lipid nanoparticle formulations of siRNA
JA Kulkarni, D Witzigmann, J Leung, YYC Tam, PR Cullis
Nanoscale 11 (45), 21733-21739, 2019
2192019
Molecular architecture and functional model of the complete yeast ESCRT-I heterotetramer
MS Kostelansky, C Schluter, YYC Tam, S Lee, R Ghirlando, B Beach, ...
Cell 129 (3), 485-498, 2007
2152007
Pex3p initiates the formation of a preperoxisomal compartment from a subdomain of the endoplasmic reticulum in Saccharomyces cerevisiae
YYC Tam, A Fagarasanu, M Fagarasanu, RA Rachubinski
Journal of Biological Chemistry 280 (41), 34933-34939, 2005
2112005
Quantitative mass spectrometry reveals a role for the GTPase Rho1p in actin organization on the peroxisome membrane
M Marelli, JJ Smith, S Jung, E Yi, AI Nesvizhskii, RH Christmas, ...
The Journal of cell biology 167 (6), 1099-1112, 2004
1782004
Design of lipid nanoparticles for in vitro and in vivo delivery of plasmid DNA
JA Kulkarni, JL Myhre, S Chen, YYC Tam, A Danescu, JM Richman, ...
Nanomedicine: Nanotechnology, Biology and Medicine 13 (4), 1377-1387, 2017
1642017
Lipid nanoparticle siRNA systems for silencing the androgen receptor in human prostate cancer in vivo
JB Lee, K Zhang, YYC Tam, YK Tam, NM Belliveau, VYC Sung, PJC Lin, ...
International Journal of Cancer 131 (5), E781-E790, 2012
1612012
Development of lipid nanoparticle formulations of siRNA for hepatocyte gene silencing following subcutaneous administration
S Chen, YYC Tam, PJC Lin, AKK Leung, YK Tam, PR Cullis
Journal of controlled release 196, 106-112, 2014
1422014
Lipid nanoparticles for short interfering RNA delivery
AKK Leung, YYC Tam, PR Cullis
Advances in genetics 88, 71-110, 2014
1412014
Inp1p is a peroxisomal membrane protein required for peroxisome inheritance in Saccharomyces cerevisiae
M Fagarasanu, A Fagarasanu, YYC Tam, JD Aitchison, RA Rachubinski
The Journal of cell biology 169 (5), 765-775, 2005
1362005
Pex11-related Proteins in Peroxisome Dynamics: A Role for the Novel Peroxin Pex27p in Controlling Peroxisome Size and Number in Saccharomyces cerevisiae
YYC Tam, JC Torres-Guzman, FJ Vizeacoumar, JJ Smith, M Marelli, ...
Molecular biology of the cell 14 (10), 4089-4102, 2003
1312003
YHR150w and YDR479c encode peroxisomal integral membrane proteins involved in the regulation of peroxisome number, size, and distribution in Saccharomyces cerevisiae
FJ Vizeacoumar, JC Torres-Guzman, YYC Tam, JD Aitchison, ...
The Journal of cell biology 161 (2), 321-332, 2003
1252003
Influence of cationic lipid composition on uptake and intracellular processing of lipid nanoparticle formulations of siRNA
PJC Lin, YYC Tam, I Hafez, A Sandhu, S Chen, MA Ciufolini, IR Nabi, ...
Nanomedicine: Nanotechnology, Biology and Medicine 9 (2), 233-246, 2013
992013
Fusion-dependent formation of lipid nanoparticles containing macromolecular payloads
JA Kulkarni, D Witzigmann, J Leung, R van der Meel, J Zaifman, ...
Nanoscale 11 (18), 9023-9031, 2019
962019
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