Fluorogenic assay for inhibitors of HIV-1 protease with sub-picomolar affinity IW Windsor, RT Raines Scientific reports 5, 11286, 2015 | 29 | 2015 |
Sub-picomolar inhibition of HIV-1 protease with a boronic acid IW Windsor, MJ Palte, JC Lukesh III, B Gold, KT Forest, RT Raines Journal of the American Chemical Society 140 (43), 14015-14018, 2018 | 28 | 2018 |
Stilbene boronic acids form a covalent bond with human transthyretin and inhibit its aggregation TP Smith, IW Windsor, KT Forest, RT Raines Journal of medicinal chemistry 60 (18), 7820-7834, 2017 | 14 | 2017 |
Stereoelectronic effects impact glycan recognition CM McMahon, CR Isabella, IW Windsor, P Kosma, RT Raines, ... Journal of the American Chemical Society 142 (5), 2386-2395, 2020 | 13 | 2020 |
An n→π* Interaction in the Bound Substrate of Aspartic Proteases Replicates the Oxyanion Hole IW Windsor, B Gold, RT Raines ACS catalysis 9 (2), 1464-1471, 2018 | 12 | 2018 |
Nucleoside tetra-and pentaphosphates prepared using a tetraphosphorylation reagent are potent inhibitors of ribonuclease A SM Shepard, IW Windsor, RT Raines, CC Cummins Journal of the American Chemical Society 141 (46), 18400-18404, 2019 | 9 | 2019 |
A substrate selected by phage display exhibits enhanced side-chain hydrogen bonding to HIV-1 protease IW Windsor, RT Raines Acta Crystallographica Section D: Structural Biology 74 (7), 690-694, 2018 | 6 | 2018 |
Boronic acid inhibitors of HIV protease RT Raines, I Windsor, M Palte, J Lukesh US Patent 9,738,664, 2017 | 1 | 2017 |
Circular strained zymogen compositions and methods of use R Raines, I Windsor US Patent App. 16/913,924, 2020 | | 2020 |
Palladium–Protein Oxidative Addition Complexes by Amine-Selective Acylation HH Dhanjee, I Buslov, IW Windsor, RT Raines, BL Pentelute, ... Journal of the American Chemical Society, 2020 | | 2020 |
Boronic acid with high oxidative stability and utility in biological contexts B Graham, IW Windsor, B Gold, R Raines ChemRxiv, 2020 | | 2020 |
Circular zymogens of human ribonuclease 1 IW Windsor, CJ Graff, RT Raines Protein Science 28 (9), 1713-1719, 2019 | | 2019 |
HIV-1 protease as a target for antiretroviral therapy IW Windsor Massachusetts Institute of Technology, 2019 | | 2019 |
HIV protease as a target for novel antiretroviral therapies I Windsor, B Gold, D Dudley, B Graham, M Palte, J Lukesh, T Smith, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 256, 2018 | | 2018 |
Boronic Acid Inhibitors of HIV Protease RT Raines, I Windsor, M Palte, J Lukesh US Patent App. 15/662,813, 2017 | | 2017 |
Supporting Information for Nucleoside Tetra-and Pentaphosphates Prepared Using a Tetraphosphorylation Reagent are Potent Inhibitors of Ribonuclease A SM Shepard, IW Windsor, RT Raines, CC Cummins | | |