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Zhuoran Yin
Zhuoran Yin
Research Fellow, Department of Ophthalmology, Mass Eye and Ear, Harvard Medical School
Geverifieerd e-mailadres voor bwh.harvard.edu - Homepage
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Induction of a common microglia gene expression signature by aging and neurodegenerative conditions: a co-expression meta-analysis
IR Holtman, DD Raj, JA Miller, W Schaafsma, Z Yin, N Brouwer, PD Wes, ...
Acta neuropathologica communications 3 (1), 1-18, 2015
5352015
Type I interferon response drives neuroinflammation and synapse loss in Alzheimer disease
ER Roy, B Wang, Y Wan, G Chiu, A Cole, Z Yin, NE Propson, Y Xu, ...
The Journal of clinical investigation 130 (4), 1912-1930, 2020
2732020
Immune hyperreactivity of Aβ plaque-associated microglia in Alzheimer's disease
Z Yin, D Raj, N Saiepour, D Van Dam, N Brouwer, IR Holtman, BJL Eggen, ...
Neurobiology of aging 55, 115-122, 2017
2172017
Microglia, lifestyle stress, and neurodegeneration
C Madore, Z Yin, J Leibowitz, O Butovsky
Immunity 52 (2), 222-240, 2020
1942020
Selective removal of astrocytic APOE4 strongly protects against tau-mediated neurodegeneration and decreases synaptic phagocytosis by microglia
C Wang, M Xiong, M Gratuze, X Bao, Y Shi, PS Andhey, M Manis, ...
Neuron 109 (10), 1657-1674. e7, 2021
1562021
Increased white matter inflammation in aging-and Alzheimer’s disease brain
D Raj, Z Yin, M Breur, J Doorduin, IR Holtman, M Olah, IJ Mantingh-Otter, ...
Frontiers in molecular neuroscience 10, 206, 2017
1482017
Low-fat diet with caloric restriction reduces white matter microglia activation during aging
Z Yin, DD Raj, W Schaafsma, RA Van der Heijden, SM Kooistra, ...
Frontiers in molecular neuroscience, 65, 2018
462018
Progressive motor deficit is mediated by the denervation of neuromuscular junctions and axonal degeneration in transgenic mice expressing mutant (P301S) tau protein
Z Yin, F Valkenburg, BE Hornix, I Mantingh-Otter, X Zhou, M Mari, ...
Journal of Alzheimer's Disease 60 (s1), S41-S57, 2017
282017
Apolipoprotein E4 impairs the response of neurodegenerative retinal microglia and prevents neuronal loss in glaucoma
MA Margeta, Z Yin, C Madore, KM Pitts, SM Letcher, J Tang, S Jiang, ...
Immunity 55 (9), 1627-1644. e7, 2022
272022
Sex-specific transcriptome of spinal microglia in neuropathic pain due to peripheral nerve injury
NT Fiore, Z Yin, D Guneykaya, CD Gauthier, J Hayes, A D’Hary, ...
Glia, 2022
242022
Identification of a protective microglial state mediated by miR-155 and interferon-γ signaling in a mouse model of Alzheimer’s disease
Z Yin, S Herron, S Silveira, K Kleemann, C Gauthier, D Mallah, Y Cheng, ...
Nature Neuroscience, 1-12, 2023
122023
Regulating microglial miR-155 transcriptional phenotype alleviates Alzheimer’s-induced retinal vasculopathy by limiting Clec7a/Galectin-3+ neurodegenerative microglia
H Shi, Z Yin, Y Koronyo, DT Fuchs, J Sheyn, MR Davis, JW Wilson, ...
Acta Neuropathologica Communications 10 (1), 1-22, 2022
102022
IL-33 promotes mouse keratinocyte-derived chemokine, an IL-8 homologue, expression in airway smooth muscle cells in ovalbumin-sensitized mice
W Wu, Y Xu, X He, Y Lu, Y Guo, Z Yin, J Xie, J Zhao
Asian Pac J Allergy Immunol 32 (4), 337-44, 2014
72014
Do neuroimaging results impact prognosis of epilepsy surgery? A meta-analysis
Z Yin, H Kang, W Wu, M Wang, S Zhu
Journal of Huazhong University of Science and Technology [Medical Sciences …, 2013
42013
APOE4 impairs the microglial response in Alzheimer’s disease by inducing TGFβ-mediated checkpoints
Z Yin, N Rosenzweig, KL Kleemann, X Zhang, W Brandão, MA Margeta, ...
Nature Immunology, 1-15, 2023
32023
Vγ1 and Vγ4 gamma-delta T cells play opposing roles in the immunopathology of traumatic brain injury in males
H Abou-El-Hassan, RM Rezende, S Izzy, G Gabriely, T Yahya, ...
Nature Communications 14 (1), 4286, 2023
32023
Sex-specific microglia state in the Neuroligin-4 knock-out mouse model of autism spectrum disorder
D Guneykaya, B Ugursu, F Logiacco, O Popp, MA Feiks, N Meyer, ...
Brain, Behavior, and Immunity 111, 61-75, 2023
12023
Suppressing ApoE ε4 allele protects against signs of Alzheimer’s disease
Z Yin, N Rosenzweig, KL Kleemann, X Zhang, W Brandão, MA Margeta, ...
2023
APOE4 impairs Microglia-Astrocyte Crosstalk in Alzheimer Disease
K Kleemann, N Rosenzweig, Z Yin, X Zhang, WN Brandao, M Margeta, ...
Alzheimer's Association International Conference, 2023
2023
Deletion of miR-155 in microglia enhances their response to neurodegeneration and mitigates cognitive impairment in a mouse model of Alzheimer’s disease
Z Yin, S Herron, S Silveira, K Kleemann, C Gauthier, D Mallah, C Cheng, ...
Alzheimer's Association International Conference, 2023
2023
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Artikelen 1–20