Jules Heuberger
Jules Heuberger
Clinical Scientist
Verified email at chdr.nl
Title
Cited by
Cited by
Year
Erythropoietin doping in cycling: lack of evidence for efficacy and a negative risk–benefit
JAAC Heuberger, JM Cohen Tervaert, FML Schepers, ADB Vliegenthart, ...
British journal of clinical pharmacology 75 (6), 1406-1421, 2013
772013
When is protein binding important?
J Heuberger, S Schmidt, H Derendorf
Journal of pharmaceutical sciences 102 (9), 3458-3467, 2013
712013
Effects on spasticity and neuropathic pain of an oral formulation of Δ9-tetrahydrocannabinol in patients with progressive multiple sclerosis
G van Amerongen, K Kanhai, AC Baakman, J Heuberger, E Klaassen, ...
Clinical therapeutics 40 (9), 1467-1482, 2018
592018
Population pharmacokinetic model of THC integrates oral, intravenous, and pulmonary dosing and characterizes short-and long-term pharmacokinetics
JAAC Heuberger, Z Guan, OO Oyetayo, L Klumpers, PD Morrison, ...
Clinical pharmacokinetics 54 (2), 209-219, 2015
522015
Effects of erythropoietin on cycling performance of well trained cyclists: a double-blind, randomised, placebo-controlled trial
JAAC Heuberger, JI Rotmans, P Gal, FE Stuurman, J van't Westende, ...
The Lancet Haematology 4 (8), e374-e386, 2017
482017
Review of WADA prohibited substances: limited evidence for performance-enhancing effects
JAAC Heuberger, AF Cohen
Sports Medicine 49 (4), 525-539, 2019
452019
In vitro pharmacokinetics/pharmacodynamics of the combination of avibactam and aztreonam against MDR organisms
SKB Sy, ME Beaudoin, L Zhuang, KI Löblein, C Lux, M Kissel, R Tremmel, ...
Journal of Antimicrobial Chemotherapy 71 (7), 1866-1880, 2016
332016
Indanes—properties, preparation, and presence in ligands for G protein coupled receptors
M Vilums, J Heuberger, LH Heitman, AP IJzerman
Medicinal research reviews 35 (6), 1097-1126, 2015
312015
Accelerated development of the dual orexin receptor antagonist ACT‐541468: integration of a microtracer in a first‐in‐human study
C Muehlan, J Heuberger, PE Juif, M Croft, J van Gerven, J Dingemanse
Clinical Pharmacology & Therapeutics 104 (5), 1022-1029, 2018
282018
Repeatability and predictive value of lactate threshold concepts in endurance sports
JAAC Heuberger, P Gal, FE Stuurman, WAS de Muinck Keizer, ...
PloS one 13 (11), e0206846, 2018
272018
Acute effects of riluzole and retigabine on axonal excitability in patients with amyotrophic lateral sclerosis: a randomized, double‐blind, placebo‐controlled, crossover trial
MO Kovalchuk, JAAC Heuberger, BTHM Sleutjes, D Ziagkos, ...
Clinical Pharmacology & Therapeutics 104 (6), 1136-1145, 2018
242018
The oral splicing modifier RG7800 increases full length survival of motor neuron 2 mRNA and survival of motor neuron protein: Results from trials in healthy adults and patients …
H Kletzl, A Marquet, A Günther, W Tang, J Heuberger, GJ Groeneveld, ...
Neuromuscular Disorders 29 (1), 21-29, 2019
232019
DNL 104, a Centrally Penetrant RIPK 1 Inhibitor, Inhibits RIP 1 Kinase Phosphorylation in a Randomized Phase I Ascending Dose Study in Healthy Volunteers
HW Grievink, JAAC Heuberger, F Huang, R Chaudhary, WAJ Birkhoff, ...
Clinical Pharmacology & Therapeutics 107 (2), 406-414, 2020
182020
Pharmacokinetic modeling and dose selection in a randomized, double-blind, placebo-controlled trial of a human recombinant alkaline phosphatase in healthy volunteers
E Peters, JAAC Heuberger, R Tiessen, A van Elsas, R Masereeuw, ...
Clinical pharmacokinetics 55 (10), 1227-1237, 2016
152016
A Markov chain model to evaluate the effect of CYP3A5 and ABCB1 polymorphisms on adverse events associated with tacrolimus in pediatric renal transplantation
SKB Sy, J Heuberger, S Shilbayeh, DJ Conrado, H Derendorf
The AAPS journal 15 (4), 1189-1199, 2013
132013
Futility of current urine salbutamol doping control
JAAC Heuberger, SC van Dijkman, AF Cohen
British journal of clinical pharmacology 84 (8), 1830-1838, 2018
112018
Tolerance to opioid‐induced respiratory depression in chronic high‐dose opioid users: a model‐based comparison with opioid‐naïve individuals
MH Algera, E Olofsen, L Moss, RL Dobbins, M Niesters, M van Velzen, ...
Clinical Pharmacology & Therapeutics 109 (3), 637-645, 2021
52021
Recombinant human erythropoietin does not affect several microvascular parameters in well‐trained cyclists
WAJ Birkhoff, JAAC Heuberger, TE Post, P Gal, FE Stuurman, J Burggraaf, ...
Physiological reports 6 (24), e13924, 2018
52018
The influence of personality on the sensitivity to subjective effects of Δ9-tetrahydrocannabinol
D Kleinloog, J Stevens, J Heuberger, P Spinhoven, J van Gerven
Psychiatry research 220 (3), 945-953, 2014
52014
Sensitivity and specificity of detection methods for erythropoietin doping in cyclists
JAAC Heuberger, P Van Eenoo, JI Rotmans, P Gal, FE Stuurman, TE Post, ...
Drug testing and analysis 11 (9), 1290-1301, 2019
42019
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