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Lukas Dow
Lukas Dow
Associate Professor, Meyer Cancer Center, Weill Cornell Medicine
Verified email at med.cornell.edu - Homepage
Title
Cited by
Cited by
Year
Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regeneration
CA Lindemans, M Calafiore, AM Mertelsmann, MH O’connor, JA Dudakov, ...
Nature 528 (7583), 560-564, 2015
9762015
Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH
J Yun, E Mullarky, C Lu, KN Bosch, A Kavalier, K Rivera, J Roper, IIC Chio, ...
Science 350 (6266), 1391-1396, 2015
8742015
Inducible in vivo genome editing with CRISPR-Cas9
LE Dow, J Fisher, KP O'rourke, A Muley, ER Kastenhuber, G Livshits, ...
Nature biotechnology 33 (4), 390-394, 2015
5502015
Apc restoration promotes cellular differentiation and reestablishes crypt homeostasis in colorectal cancer
LE Dow, KP O’Rourke, J Simon, DF Tschaharganeh, JH van Es, ...
Cell 161 (7), 1539-1552, 2015
5472015
Transcriptional plasticity promotes primary and acquired resistance to BET inhibition
P Rathert, M Roth, T Neumann, F Muerdter, JS Roe, M Muhar, S Deswal, ...
Nature 525 (7570), 543-547, 2015
4872015
A rectal cancer organoid platform to study individual responses to chemoradiation
K Ganesh, C Wu, KP O’Rourke, BC Szeglin, Y Zheng, CEG Sauvé, ...
Nature medicine 25 (10), 1607-1614, 2019
3602019
A rapid and scalable system for studying gene function in mice using conditional RNA interference
PK Premsrirut, LE Dow, SY Kim, M Camiolo, CD Malone, C Miething, ...
Cell 145 (1), 145-158, 2011
3492011
Toolkit for evaluating genes required for proliferation and survival using tetracycline-regulated RNAi
J Zuber, K McJunkin, C Fellmann, LE Dow, MJ Taylor, GJ Hannon, ...
Nature biotechnology 29 (1), 79-83, 2011
3102011
Optimized base editors enable efficient editing in cells, organoids and mice
MP Zafra, EM Schatoff, A Katti, M Foronda, M Breinig, AY Schweitzer, ...
Nature biotechnology 36 (9), 888-893, 2018
3082018
A network of PDZ-containing proteins regulates T cell polarity and morphology during migration and immunological synapse formation
MJ Ludford-Menting, J Oliaro, F Sacirbegovic, ETY Cheah, N Pedersen, ...
Immunity 22 (6), 737-748, 2005
3072005
Wnt signaling and colorectal cancer
EM Schatoff, BI Leach, LE Dow
Current colorectal cancer reports 13 (2), 101-110, 2017
3002017
p53-dependent Nestin regulation links tumor suppression to cellular plasticity in liver cancer
DF Tschaharganeh, W Xue, DF Calvisi, M Evert, TV Michurina, LE Dow, ...
Cell 158 (3), 579-592, 2014
2412014
Genetic liver-specific AMPK activation protects against diet-induced obesity and NAFLD
D Garcia, K Hellberg, A Chaix, M Wallace, S Herzig, MG Badur, T Lin, ...
Cell reports 26 (1), 192-208. e6, 2019
2232019
Transplantation of engineered organoids enables rapid generation of metastatic mouse models of colorectal cancer
KP O'Rourke, E Loizou, G Livshits, EM Schatoff, T Baslan, E Manchado, ...
Nature biotechnology 35 (6), 577-582, 2017
2152017
CRISPR in cancer biology and therapy
A Katti, BJ Diaz, CM Caragine, NE Sanjana, LE Dow
Nature Reviews Cancer 22 (5), 259-279, 2022
2062022
The tumour-suppressor Scribble dictates cell polarity during directed epithelial migration: regulation of Rho GTPase recruitment to the leading edge
LE Dow, JS Kauffman, J Caddy, AS Peterson, SM Jane, SM Russell, ...
Oncogene 26 (16), 2272-2282, 2007
2022007
SCRIB expression is deregulated in human prostate cancer, and its deficiency in mice promotes prostate neoplasia
HB Pearson, PA Perez-Mancera, LE Dow, A Ryan, P Tennstedt, D Bogani, ...
The Journal of clinical investigation 121 (11), 4257-4267, 2011
2012011
A pipeline for the generation of shRNA transgenic mice
LE Dow, PK Premsrirut, J Zuber, C Fellmann, K McJunkin, C Miething, ...
Nature protocols 7 (2), 374-393, 2012
1932012
Loss of human Scribble cooperates with H-Ras to promote cell invasion through deregulation of MAPK signalling
LE Dow, IA Elsum, CL King, KM Kinross, HE Richardson, PO Humbert
Oncogene 27 (46), 5988-6001, 2008
1902008
Inducible in vivo silencing of Brd4 identifies potential toxicities of sustained BET protein inhibition
JE Bolden, N Tasdemir, LE Dow, JH van Es, JE Wilkinson, Z Zhao, ...
Cell reports 8 (6), 1919-1929, 2014
1892014
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