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Chang XIE
Chang XIE
Astellas Gene Therapies
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Cholesterol transport through lysosome-peroxisome membrane contacts
BB Chu, YC Liao, W Qi, C Xie, X Du, J Wang, H Yang, HH Miao, BL Li, ...
Cell 161 (2), 291-306, 2015
3872015
Genome editing with CRISPR/Cas9 in postnatal mice corrects PRKAG2 cardiac syndrome
C Xie, YP Zhang, L Song, J Luo, W Qi, J Hu, D Lu, Z Yang, J Zhang, ...
Cell Research 26 (10), 1099-1111, 2016
1272016
Cholesterol transport through the peroxisome-ER membrane contacts tethered by PI(4,5)P2 and extended synaptotagmins
J Xiao, J Luo, AO Hu, T Xiao, M Li, Z Kong, L Jiang, Z Zhou, Y Liao, C Xie, ...
Science China Life Sciences 62, 1117-1135, 2019
712019
Ezetimibe blocks the internalization of NPC1L1 and cholesterol in mouse small intestine
C Xie, ZS Zhou, N Li, Y Bian, YJ Wang, LJ Wang, BL Li, BL Song
Journal of lipid research 53 (10), 2092-2101, 2012
702012
Requirement of myosin Vb· Rab11a· Rab11-FIP2 complex in cholesterol-regulated translocation of NPC1L1 to the cell surface
BB Chu, L Ge, C Xie, Y Zhao, HH Miao, J Wang, BL Li, BL Song
Journal of biological chemistry 284 (33), 22481-22490, 2009
692009
Gpnmb secreted from liver promotes lipogenesis in white adipose tissue and aggravates obesity and insulin resistance
XM Gong, YF Li, J Luo, JQ Wang, J Wei, JQ Wang, T Xiao, C Xie, J Hong, ...
Nature Metabolism 1, 570-583, 2019
522019
AAV9-NPC1 significantly ameliorates Purkinje cell death and behavioral abnormalities in mouse NPC disease
C Xie, XM Gong, J Luo, BL Li, BL Song
Journal of Lipid Research 58 (3), 512-518, 2017
482017
Regulatory T-cell depletion in the gut caused by integrin β7 deficiency exacerbates DSS colitis by evoking aberrant innate immunity
HL Zhang, YJ Zheng, YD Pan, C Xie, H Sun, YH Zhang, MY Yuan, ...
Mucosal immunology 9 (2), 391-400, 2016
452016
The small GTPase Cdc42 interacts with Niemann-Pick C1-like 1 (NPC1L1) and controls its movement from endocytic recycling compartment to plasma membrane in a cholesterol …
C Xie, N Li, ZJ Chen, BL Li, BL Song
Journal of Biological Chemistry 286 (41), 35933-35942, 2011
422011
Ciliary Hedgehog signaling patterns the digestive system to generate mechanical forces driving elongation
Y Yang, P Paivinen, C Xie, AL Krup, TP Makela, KE Mostov, JF Reiter
Nature communications 12 (1), 7186, 2021
112021
Endoderm development requires centrioles to restrain p53-mediated apoptosis in the absence of ERK activity
C Xie, SR Abrams, V Herranz-Pérez, JM García-Verdugo, JF Reiter
Developmental cell 56 (24), 3334-3348. e6, 2021
92021
p.N1380del mutation in the pore-forming region of SCN5A gene is associated with cardiac conduction disturbance and ventricular tachycardia
Z Yang, D Lu, L Zhang, J Hu, Z Nie, C Xie, F Qiu, H Cheng, Y Yan
Acta Biochimica et Biophysica Sinica 49 (3), 270-276, 2017
52017
Bile acids-mediated intracellular cholesterol transport promotes intestinal cholesterol absorption and NPC1L1 recycling
BLS J Xiao, LW Dong, S Liu, FH Meng, C Xie, XY Lu, WJ Zhang, J Luo
Nature Communications 14, 6469, 2023
22023
Ciliary signaling-patterned smooth muscle drives tubular elongation
Y Yang, P Paivinen, C Xie, AL Krup, TP Makela, KE Mostov, JF Reiter
bioRxiv, 2020.08. 31.276295, 2020
22020
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Artikelen 1–14