Severe deficiency of the voltage-gated sodium channel NaV1. 2 elevates neuronal excitability in adult mice J Zhang, X Chen, M Eaton, J Wu, Z Ma, S Lai, A Park, TS Ahmad, Z Que, ... Cell reports 36 (5), 2021 | 44 | 2021 |
Hyperexcitability and pharmacological responsiveness of cortical neurons derived from human iPSCs carrying epilepsy-associated sodium channel Nav1. 2-L1342P genetic variant Z Que, MI Olivero-Acosta, J Zhang, M Eaton, AM Tukker, X Chen, J Wu, ... Journal of Neuroscience 41 (49), 10194-10208, 2021 | 29 | 2021 |
Generation and basic characterization of a gene‐trap knockout mouse model of Scn2a with a substantial reduction of voltage‐gated sodium channel Nav1.2 … M Eaton, J Zhang, Z Ma, AC Park, E Lietzke, CM Romero, Y Liu, ... Genes, Brain and Behavior 20 (4), e12725, 2021 | 18 | 2021 |
Deficiency of autism-related Scn2a gene in mice disrupts sleep patterns and circadian rhythms Z Ma, M Eaton, Y Liu, J Zhang, X Chen, X Tu, Y Shi, Z Que, ... Neurobiology of disease 168, 105690, 2022 | 16 | 2022 |
Multi-Electrode Array of Sensory Neurons as an In Vitro Platform to Identify the Nociceptive Response to Pharmaceutical Buffer Systems of Injectable Biologics M Eaton, Z Que, J Zhang, K Beck, R Shi, J McDermott, M Ladisch, Y Yang Pharmaceutical Research 38, 1179-1186, 2021 | 3 | 2021 |
Microglial over-pruning of synapses during development in autism-associated SCN2A-deficient mice and human cerebral organoids J Wu, J Zhang, X Chen, K Wettschurack, Z Que, BA Deming, ... Molecular Psychiatry, 1-14, 2024 | 2 | 2024 |
Sodium channel Nav1. 2-L1342P variant displaying complex biophysical properties renders hyperexcitability of cortical neurons derived from human iPSCs Z Que, MI Olivero-Acosta, J Zhang, M Eaton, WC Skarnes, Y Yang BioRxiv, 2021.01. 18.427192, 2021 | 2 | 2021 |
Human iPSC-derived microglia sense and dampen hyperexcitability of cortical neurons carrying the epilepsy-associated SCN2A-L1342P mutation Z Que, MI Olivero-Acosta, I Chen, J Zhang, K Wettschurack, J Wu, T Xiao, ... bioRxiv, 2023 | | 2023 |