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Maarten Merkx
Maarten Merkx
Professor of Protein Engineering. Eindhoven University of Technology
Geverifieerd e-mailadres voor tue.nl
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Dioxygen activation and methane hydroxylation by soluble methane monooxygenase: a tale of two irons and three proteins
M Merkx, DA Kopp, MH Sazinsky, JL Blazyk, J Müller, SJ Lippard
Angewandte Chemie International Edition 40 (15), 2782-2807, 2001
8042001
Genetically encoded FRET sensors to monitor intracellular Zn2+ homeostasis
JL Vinkenborg, TJ Nicolson, EA Bellomo, MS Koay, GA Rutter, M Merkx
Nature methods 6 (10), 737-740, 2009
4252009
Human copper transporter 2 is localized in late endosomes and lysosomes and facilitates cellular copper uptake
PVE Van den Berghe, DE Folmer, HEM Malingré, E Van Beurden, ...
Biochemical Journal 407 (1), 49-59, 2007
2232007
Quantitative understanding of the energy transfer between fluorescent proteins connected via flexible peptide linkers
TH Evers, EMWM van Dongen, AC Faesen, EW Meijer, M Merkx
Biochemistry 45 (44), 13183-13192, 2006
2182006
Fluorescently labeled collagen binding proteins allow specific visualization of collagen in tissues and live cell culture
KN Krahn, CVC Bouten, S van Tuijl, MAMJ van Zandvoort, M Merkx
Analytical biochemistry 350 (2), 177-185, 2006
1802006
Inhibition of human copper trafficking by a small molecule significantly attenuates cancer cell proliferation
J Wang, C Luo, C Shan, Q You, J Lu, S Elf, Y Zhou, Y Wen, JL Vinkenborg, ...
Nature chemistry 7 (12), 968-979, 2015
1592015
Branched KLVFF tetramers strongly potentiate inhibition of β‐Amyloid aggregation
SM Chafekar, H Malda, M Merkx, EW Meijer, D Viertl, HA Lashuel, F Baas, ...
ChemBioChem 8 (15), 1857-1864, 2007
1512007
Multivalent peptide and protein dendrimers using native chemical ligation
I van Baal, H Malda, SA Synowsky, JLJ van Dongen, TM Hackeng, ...
Angewandte Chemie 117 (32), 5180-5185, 2005
1182005
Supramolecular Control of Enzyme Activity through Cucurbit [8] uril‐Mediated Dimerization
DT Dang, HD Nguyen, M Merkx, L Brunsveld
Angewandte Chemie 125 (10), 2987-2991, 2013
1172013
Variation of linker length in ratiometric fluorescent sensor proteins allows rational tuning of Zn (II) affinity in the picomolar to femtomolar range
EMWM van Dongen, TH Evers, LM Dekkers, EW Meijer, LWJ Klomp, ...
Journal of the American Chemical Society 129 (12), 3494-3495, 2007
1152007
Tuning the flexibility of glycine-serine linkers to allow rational design of multidomain proteins
M Van Rosmalen, M Krom, M Merkx
Biochemistry 56 (50), 6565-6574, 2017
1142017
Detection of antibodies in blood plasma using bioluminescent sensor proteins and a smartphone
R Arts, I Den Hartog, SE Zijlema, V Thijssen, SHE Van Der Beelen, ...
Analytical chemistry 88 (8), 4525-4532, 2016
1102016
An optical sensor based on a photonic polymer film to detect calcium in serum
M Moirangthem, R Arts, M Merkx, APHJ Schenning
Advanced functional materials 26 (8), 1154-1160, 2016
1102016
Ratiometric fluorescent sensor proteins with subnanomolar affinity for Zn (II) based on copper chaperone domains
EMWM van Dongen, LM Dekkers, K Spijker, EW Meijer, LWJ Klomp, ...
Journal of the American Chemical Society 128 (33), 10754-10762, 2006
1072006
Paper‐based antibody detection devices using bioluminescent BRET‐switching sensor proteins
K Tenda, B van Gerven, R Arts, Y Hiruta, M Merkx, D Citterio
Angewandte Chemie International Edition 57 (47), 15369-15373, 2018
1052018
Engineering genetically encoded FRET sensors
L Lindenburg, M Merkx
Sensors 14 (7), 11691-11713, 2014
1052014
High resolution imaging of collagen organisation and synthesis using a versatile collagen specific probe
RA Boerboom, KN Krahn, RTA Megens, MAMJ van Zandvoort, M Merkx, ...
Journal of structural biology 159 (3), 392-399, 2007
1032007
Mitochondrial and ER-Targeted eCALWY Probes Reveal High Levels of Free Zn2+
P Chabosseau, E Tuncay, G Meur, EA Bellomo, A Hessels, S Hughes, ...
ACS chemical biology 9 (9), 2111-2120, 2014
1012014
Electrochemical reduction of NO by hemin adsorbed at pyrolitic graphite
MT de Groot, M Merkx, AH Wonders, MTM Koper
Journal of the American Chemical Society 127 (20), 7579-7586, 2005
1002005
Enhanced sensitivity of FRET‐based protease sensors by redesign of the GFP dimerization interface
JL Vinkenborg, TH Evers, SWA Reulen, EW Meijer, M Merkx
ChemBioChem 8 (10), 1119-1121, 2007
992007
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Artikelen 1–20