| Topoisomerase IV is a target of quinolones in Escherichia coli. AB Khodursky, EL Zechiedrich, NR Cozzarelli Proceedings of the National Academy of Sciences 92 (25), 11801-11805, 1995 | 462 | 1995 |
| The role of topoisomerase IV in partitioning bacterial replicons and the structure of catenated intermediates in DNA replication DE Adams, EM Shekhtman, EL Zechiedrich, MB Schmid, NR Cozzarelli Cell 71 (2), 277-288, 1992 | 446 | 1992 |
| Roles of topoisomerases in maintaining steady-state DNA supercoiling in Escherichia coli EL Zechiedrich, AB Khodursky, S Bachellier, R Schneider, D Chen, ... Journal of Biological Chemistry 275 (11), 8103-8113, 2000 | 395 | 2000 |
| Advances in non-viral DNA vectors for gene therapy CL Hardee, LM Arévalo-Soliz, BD Hornstein, L Zechiedrich Genes 8 (2), 65, 2017 | 368 | 2017 |
| Roles of topoisomerase IV and DNA gyrase in DNA unlinking during replication in Escherichia coli. EL Zechiedrich, NR Cozzarelli Genes & development 9 (22), 2859-2869, 1995 | 366 | 1995 |
| Catalytic function of DNA topoisomerase II N Osheroff, EL Zechiedrich, KC Gale BioEssays 13 (6), 269-275, 1991 | 334 | 1991 |
| Eukaryotic topoisomerases recognize nucleic acid topology by preferentially interacting with DNA crossovers. EL Zechiedrich, N Osheroff The EMBO journal 9 (13), 4555-4562, 1990 | 321 | 1990 |
| Topoisomerase IV, not gyrase, decatenates products of site-specific recombination inEscherichia coli EL Zechiedrich, AB Khodursky, NR Cozzarelli Genes & development 11 (19), 2580-2592, 1997 | 283 | 1997 |
| Control of the AcrAB multidrug efflux pump by quorum‐sensing regulator SdiA S Rahmati, S Yang, AL Davidson, EL Zechiedrich Molecular microbiology 43 (3), 677-685, 2002 | 251 | 2002 |
| Expression of Multidrug Efflux Pump Genes acrAB-tolC, mdfA, and norE in Escherichia coli Clinical Isolates as a Function of Fluoroquinolone and Multidrug … MC Swick, SK Morgan-Linnell, KM Carlson, L Zechiedrich Antimicrobial agents and chemotherapy 55 (2), 921-924, 2011 | 240 | 2011 |
| Mechanisms Accounting for Fluoroquinolone Resistance in Escherichia coli Clinical Isolates SK Morgan-Linnell, L Becnel Boyd, D Steffen, L Zechiedrich Antimicrobial agents and chemotherapy 53 (1), 235-241, 2009 | 211 | 2009 |
| Calcium-promoted DNA cleavage by eukaryotic topoisomerase II: trapping the covalent enzyme-DNA complex in an active form N Osheroff, EL Zechiedrich Biochemistry 26 (14), 4303-4309, 1987 | 200 | 1987 |
| Structural diversity of supercoiled DNA RN Irobalieva, JM Fogg, DJ Catanese Jr, T Sutthibutpong, M Chen, ... Nature communications 6 (1), 8440, 2015 | 181 | 2015 |
| Double-stranded DNA cleavage/religation reaction of eukaryotic topoisomerase II: evidence for a nicked DNA intermediate EL Zechiedrich, K Christiansen, AH Andersen, O Westergaard, N Osheroff Biochemistry 28 (15), 6229-6236, 1989 | 174 | 1989 |
| Relative contributions of the AcrAB, MdfA and NorE efflux pumps to quinolone resistance in Escherichia coli S Yang, SR Clayton, EL Zechiedrich Journal of Antimicrobial Chemotherapy 51 (3), 545-556, 2003 | 154 | 2003 |
| Topoisomerase IV, alone, unknots DNA in E. coli RW Deibler, S Rahmati, EL Zechiedrich Genes & development 15 (6), 748-761, 2001 | 150 | 2001 |
| Quorum sensing and multidrug transporters in Escherichia coli S Yang, CR Lopez, EL Zechiedrich Proceedings of the National Academy of Sciences 103 (7), 2386-2391, 2006 | 146 | 2006 |
| DNA disentangling by type-2 topoisomerases GR Buck, EL Zechiedrich Journal of molecular biology 340 (5), 933-939, 2004 | 121 | 2004 |
| Processive recombination by wild-type Gin and an enhancer-independent mutant: insight into the mechanisms of recombination selectivity and strand exchange NJ Crisona, R Kanaar, TN Gonzalez, EL Zechiedrich, A Klippel, ... Journal of molecular biology 243 (3), 437-457, 1994 | 111 | 1994 |
| The why and how of DNA unlinking Z Liu, RW Deibler, HS Chan, L Zechiedrich Nucleic acids research 37 (3), 661-671, 2009 | 105 | 2009 |
Jonathan FoggSenior Staff Scientist, Baylor College of MedicineVerified email at bcm.edu
