Jacco van Rheenen
Jacco van Rheenen
Professor at the UMC utrecht and group leader Netherlands Cancer Institute
Verified email at
Cited by
Cited by
Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells
HJ Snippert, LG Van Der Flier, T Sato, JH Van Es, M Van Den Born, ...
Cell 143 (1), 134-144, 2010
In vivo imaging reveals extracellular vesicle-mediated phenocopying of metastatic behavior
A Zomer, C Maynard, FJ Verweij, A Kamermans, R Schäfer, E Beerling, ...
Cell 161 (5), 1046-1057, 2015
Collagen-based cell migration models in vitro and in vivo
K Wolf, S Alexander, V Schacht, LM Coussens, UH von Andrian, ...
Seminars in cell & developmental biology 20 (8), 931-941, 2009
Intestinal crypt homeostasis revealed at single-stem-cell level by in vivo live imaging
L Ritsma, SIJ Ellenbroek, A Zomer, HJ Snippert, FJ De Sauvage, ...
Nature 507 (7492), 362-365, 2014
Cortactin regulates cofilin and N-WASp activities to control the stages of invadopodium assembly and maturation
M Oser, H Yamaguchi, CC Mader, JJ Bravo-Cordero, M Arias, X Chen, ...
Journal of Cell Biology 186 (4), 571-587, 2009
Intravital imaging of metastatic behavior through a mammary imaging window
D Kedrin, B Gligorijevic, J Wyckoff, VV Verkhusha, J Condeelis, JE Segall, ...
Nature methods 5 (12), 1019-1021, 2008
Vessel co-option mediates resistance to anti-angiogenic therapy in liver metastases
S Frentzas, E Simoneau, VL Bridgeman, PB Vermeulen, S Foo, ...
Nature medicine 22 (11), 1294-1302, 2016
Plasticity between epithelial and mesenchymal states unlinks EMT from metastasis-enhancing stem cell capacity
E Beerling, D Seinstra, E de Wit, L Kester, D van der Velden, C Maynard, ...
Cell reports 14 (10), 2281-2288, 2016
Reg4+ deep crypt secretory cells function as epithelial niche for Lgr5+ stem cells in colon
N Sasaki, N Sachs, K Wiebrands, SIJ Ellenbroek, A Fumagalli, ...
Proceedings of the National Academy of Sciences 113 (37), E5399-E5407, 2016
Quantifying exosome secretion from single cells reveals a modulatory role for GPCR signaling
FJ Verweij, MP Bebelman, CR Jimenez, JJ Garcia-Vallejo, H Janssen, ...
Journal of Cell Biology 217 (3), 1129-1142, 2018
Tissue-resident memory CD8+ T cells continuously patrol skin epithelia to quickly recognize local antigen
S Ariotti, JB Beltman, G Chodaczek, ME Hoekstra, AE Van Beek, ...
Proceedings of the National Academy of Sciences 109 (48), 19739-19744, 2012
EGF-induced PIP2 hydrolysis releases and activates cofilin locally in carcinoma cells
J Van Rheenen, X Song, W Van Roosmalen, M Cammer, X Chen, ...
The Journal of cell biology 179 (6), 1247-1259, 2007
Correcting confocal acquisition to optimize imaging of fluorescence resonance energy transfer by sensitized emission
J van Rheenen, M Langeslag, K Jalink
Biophysical journal 86 (4), 2517-2529, 2004
Surgical implantation of an abdominal imaging window for intravital microscopy
L Ritsma, EJA Steller, SIJ Ellenbroek, O Kranenburg, IHM Borel Rinkes, ...
Nature protocols 8 (3), 583-594, 2013
Integrins control motile strategy through a Rho–cofilin pathway
EHJ Danen, J van Rheenen, W Franken, S Huveneers, P Sonneveld, ...
The Journal of cell biology 169 (3), 515-526, 2005
A versatile toolkit to produce sensitive FRET biosensors to visualize signaling in time and space
RD Fritz, M Letzelter, A Reimann, K Martin, L Fusco, L Ritsma, B Ponsioen, ...
Science signaling 6 (285), rs12-rs12, 2013
Genetic dissection of colorectal cancer progression by orthotopic transplantation of engineered cancer organoids
A Fumagalli, J Drost, SJE Suijkerbuijk, R Van Boxtel, J De Ligt, ...
Proceedings of the National Academy of Sciences 114 (12), E2357-E2364, 2017
Cell motility and cytoskeletal regulation in invasion and metastasis
D Kedrin, J van Rheenen, L Hernandez, J Condeelis, JE Segall
Journal of mammary gland biology and neoplasia 12, 143-152, 2007
Plasticity of Lgr5-negative cancer cells drives metastasis in colorectal cancer
A Fumagalli, KC Oost, L Kester, J Morgner, L Bornes, L Bruens, ...
Cell stem cell 26 (4), 569-578. e7, 2020
Imaging hallmarks of cancer in living mice
SIJ Ellenbroek, J Van Rheenen
Nature Reviews Cancer 14 (6), 406-418, 2014
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