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Lawrence A. Loeb
Lawrence A. Loeb
Adresse e-mail validée de u.washington.edu
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8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes GT and AC substitutions.
KC Cheng, DS Cahill, H Kasai, S Nishimura, LA Loeb
Journal of biological chemistry 267 (1), 166-172, 1992
23861992
Mutator phenotype may be required for multistage carcinogenesis
LA Loeb
Cancer research 51 (12), 3075-3079, 1991
18921991
Fidelity of HIV-1 reverse transcriptase
BD Preston, BJ Poiesz, LA Loeb
Science 242 (4882), 1168-1171, 1988
13701988
Mutagenesis by apurinic/apyrimidinic sites
LA Loeb, BD Preston
Annual review of genetics 20 (1), 201-230, 1986
12511986
Detection of ultra-rare mutations by next-generation sequencing
MW Schmitt, SR Kennedy, JJ Salk, EJ Fox, JB Hiatt, LA Loeb
Proceedings of the National Academy of Sciences 109 (36), 14508-14513, 2012
11232012
Multiple mutations and cancer
LA Loeb, KR Loeb, JP Anderson
Proceedings of the National Academy of Sciences 100 (3), 776-781, 2003
11022003
A mutator phenotype in cancer
LA Loeb
Cancer research 61 (8), 3230-3239, 2001
10682001
Environmental and chemical carcinogenesis
GN Wogan, SS Hecht, JS Felton, AH Conney, LA Loeb
Seminars in cancer biology 14 (6), 473-486, 2004
8802004
The contribution of endogenous sources of DNA damage to the multiple mutations in cancer
AL Jackson, LA Loeb
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 477 (1 …, 2001
8742001
Reactive oxygen species in tumorigenesis
DI Feig, TM Reid, LA Loeb
Cancer research 54 (7_Supplement), 1890s-1894s, 1994
7911994
Microsatellite instability: marker of a mutator phenotype in cancer
LA Loeb
Cancer research 54, 5059-5059, 1994
7581994
Protein tolerance to random amino acid change
HH Guo, J Choe, LA Loeb
Proceedings of the National Academy of Sciences 101 (25), 9205-9210, 2004
7422004
The Werner syndrome protein is a DNA helicase
MD Gray, JC Shen, AS Kamath-Loeb, A Blank, BL Sopher, GM Martin, ...
Nature genetics 17 (1), 100-103, 1997
7321997
Fidelity of DNA synthesis
LA Loeb, TA Kunkel
Annual review of biochemistry 51 (1), 429-457, 1982
6941982
Errors in DNA replication as a basis of malignant changes
LA Loeb, CF Springgate, N Battula
Cancer research 34 (9), 2311-2321, 1974
6681974
Significance of multiple mutations in cancer
KR Loeb, LA Loeb
Carcinogenesis 21 (3), 379-385, 2000
6172000
Infidelity of DNA synthesis in vitro: screening for potential metal mutagens or carcinogens
MA Sirover, LA Loeb
Science 194 (4272), 1434-1436, 1976
5611976
Overexpression of catalase targeted to mitochondria attenuates murine cardiac aging
DF Dai, LF Santana, M Vermulst, DM Tomazela, MJ Emond, MJ MacCoss, ...
Circulation 119 (21), 2789-2797, 2009
5282009
Detecting ultralow-frequency mutations by Duplex Sequencing
SR Kennedy, MW Schmitt, EJ Fox, BF Kohrn, JJ Salk, EH Ahn, MJ Prindle, ...
Nature protocols 9 (11), 2586-2606, 2014
5272014
Human cancers express mutator phenotypes: origin, consequences and targeting
LA Loeb
Nature Reviews Cancer 11 (6), 450-457, 2011
4902011
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