|A biomarker that identifies senescent human cells in culture and in aging skin in vivo|
GP Dimri, X Lee, G Basile, M Acosta, G Scott, C Roskelley, EE Medrano, ...
Proceedings of the National Academy of Sciences 92 (20), 9363-9367, 1995
|Control of the replicative life span of human fibroblasts by p16 and the polycomb protein Bmi-1|
K Itahana, Y Zou, Y Itahana, JL Martinez, C Beausejour, JJL Jacobs, ...
Molecular and cellular biology 23 (1), 389-401, 2003
|Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14ARF tumor suppressor|
GP Dimri, K Itahana, M Acosta, J Campisi
Molecular and cellular biology 20 (1), 273-285, 2000
|The Bmi-1 oncogene induces telomerase activity and immortalizes human mammary epithelial cells|
GP Dimri, JL Martinez, JJL Jacobs, P Keblusek, K Itahana, ...
Cancer research 62 (16), 4736-4745, 2002
|Regulation of cellular senescence by p53|
K Itahana, G Dimri, J Campisi
European journal of biochemistry 268 (10), 2784-2791, 2001
|Methods to detect biomarkers of cellular senescence|
K Itahana, J Campisi, GP Dimri
Biological Aging, 21-31, 2007
|Bmi-1 is a novel molecular marker of nasopharyngeal carcinoma progression and immortalizes primary human nasopharyngeal epithelial cells|
LB Song, MS Zeng, WT Liao, L Zhang, HY Mo, WL Liu, JY Shao, QL Wu, ...
Cancer research 66 (12), 6225-6232, 2006
|What has senescence got to do with cancer?|
Cancer cell 7 (6), 505-512, 2005
|Mechanisms of cellular senescence in human and mouse cells|
K Itahana, J Campisi, GP Dimri
Biogerontology 5 (1), 1-10, 2004
|Human papillomavirus oncoprotein E6 inactivates the transcriptional coactivator human ADA3|
A Kumar, Y Zhao, G Meng, M Zeng, S Srinivasan, LM Delmolino, Q Gao, ...
Molecular and cellular biology 22 (16), 5801-5812, 2002
|Mammary epithelial cell transformation: insights from cell culture and mouse models|
G Dimri, H Band, V Band
Breast Cancer Research 7 (4), 1-9, 2005
|Elevated Bmi-1 expression is associated with dysplastic cell transformation during oral carcinogenesis and is required for cancer cell replication and survival|
MK Kang, RH Kim, SJ Kim, FK Yip, KH Shin, GP Dimri, R Christensen, ...
British Journal of Cancer 96 (1), 126-133, 2007
|Mel-18, a polycomb group protein, regulates cell proliferation and senescence via transcriptional repression of Bmi-1 and c-Myc oncoproteins|
WJ Guo, S Datta, V Band, GP Dimri
Molecular biology of the cell 18 (2), 536-546, 2007
|Mel-18 acts as a tumor suppressor by repressing Bmi-1 expression and down-regulating Akt activity in breast cancer cells|
WJ Guo, MS Zeng, A Yadav, LB Song, BH Guo, V Band, GP Dimri
Cancer research 67 (11), 5083-5089, 2007
|Inhibition of E2F activity by the cyclin-dependent protein kinase inhibitor p21 in cells expressing or lacking a functional retinoblastoma protein.|
GP Dimri, M Nakanishi, PY Desprez, JR Smith, J Campisi
Molecular and cellular biology 16 (6), 2987-2997, 1996
|Regulation of two E2F-related genes in presenescent and senescent human fibroblasts.|
GP Dimri, E Hara, J Campisi
Journal of Biological Chemistry 269 (23), 16180-16186, 1994
|Control of replicative senescence|
Handbook of the Biology of Aging 121, 1996
|Dietary omega-3 polyunsaturated fatty acids suppress expression of EZH2 in breast cancer cells|
M Dimri, PV Bommi, AA Sahasrabuddhe, JD Khandekar, GP Dimri
Carcinogenesis 31 (3), 489-495, 2010
|Bmi-1 cooperates with H-Ras to transform human mammary epithelial cells via dysregulation of multiple growth-regulatory pathways|
S Datta, MJ Hoenerhoff, P Bommi, R Sainger, WJ Guo, M Dimri, H Band, ...
Cancer research 67 (21), 10286-10295, 2007
|CpG methylation as a basis for breast tumor-specific loss of NES1/kallikrein 10 expression|
B Li, J Goyal, S Dhar, G Dimri, E Evron, S Sukumar, DE Wazer, V Band
Cancer research 61 (21), 8014-8021, 2001