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Shinji Okitsu
Shinji Okitsu
EMD Serono Research Institute
Verified email at emdserono.com
Title
Cited by
Cited by
Year
Molecular programming of B cell memory
M McHeyzer-Williams, S Okitsu, N Wang, L McHeyzer-Williams
Nature Reviews Immunology 12 (1), 24-34, 2012
5882012
Class-switched memory B cells remodel BCRs within secondary germinal centers
LJ McHeyzer-Williams, PJ Milpied, SL Okitsu, MG McHeyzer-Williams
Nature immunology 16 (3), 296-305, 2015
2692015
Divergent transcriptional programming of class-specific B cell memory by T-bet and RORα
NS Wang, LJ McHeyzer-Williams, SL Okitsu, TP Burris, SL Reiner, ...
Nature immunology 13 (6), 604-611, 2012
2002012
High-throughput assay and discovery of small molecules that interrupt malaria transmission
DM Plouffe, M Wree, AY Du, S Meister, F Li, K Patra, A Lubar, SL Okitsu, ...
Cell host & microbe 19 (1), 114-126, 2016
1652016
Evidence of blood stage efficacy with a virosomal malaria vaccine in a phase IIa clinical trial
FM Thompson, DW Porter, SL Okitsu, N Westerfeld, D Vogel, S Todryk, ...
PLoS One 3 (1), e1493, 2008
1312008
TLR7 and TLR8 differentially activate the IRF and NF-κB pathways in specific cell types to promote inflammation
AT Bender, E Tzvetkov, A Pereira, Y Wu, S Kasar, MM Przetak, J Vlach, ...
Immunohorizons 4 (2), 93-107, 2020
802020
A randomized placebo-controlled phase Ia malaria vaccine trial of two virosome-formulated synthetic peptides in healthy adult volunteers
B Genton, G Pluschke, L Degen, AR Kammer, N Westerfeld, SL Okitsu, ...
PloS one 2 (10), e1018, 2007
722007
Btk inhibition treats TLR7/IFN driven murine lupus
AT Bender, A Pereira, K Fu, E Samy, Y Wu, L Liu-Bujalski, R Caldwell, ...
Clinical immunology 164, 65-77, 2016
612016
A virosomal malaria peptide vaccine elicits a long-lasting sporozoite-inhibitory antibody response in a phase 1a clinical trial
SL Okitsu, O Silvie, N Westerfeld, M Curcic, AR Kammer, MS Mueller, ...
PloS one 2 (12), e1278, 2007
602007
Structure-activity-based design of a synthetic malaria peptide eliciting sporozoite inhibitory antibodies in a virosomal formulation
SL Okitsu, U Kienzl, K Moehle, O Silvie, E Peduzzi, MS Mueller, ...
Chemistry & Biology 14 (5), 577-587, 2007
482007
Discovery of M5049: a novel selective toll-like receptor 7/8 inhibitor for treatment of autoimmunity
J Vlach, AT Bender, M Przetak, A Pereira, A Deshpande, TL Johnson, ...
Journal of Pharmacology and Experimental Therapeutics 376 (3), 397-409, 2021
432021
Antibodies elicited by a virosomally formulated Plasmodium falciparum serine repeat antigen-5 derived peptide detect the processed 47 kDa fragment both in sporozoites and …
SL Okitsu, F Boato, MS Mueller, DB Li, D Vogel, N Westerfeld, ...
Peptides 28 (10), 2051-2060, 2007
292007
Antibody and T‐cell responses associated with experimental human malaria infection or vaccination show limited relationships
KM Walker, S Okitsu, DW Porter, C Duncan, M Amacker, G Pluschke, ...
Immunology 145 (1), 71-81, 2015
272015
Preclinical profiling of the immunogenicity of a two-component subunit malaria vaccine candidate based on virosome technology
SL Okitsu, MS Mueller, M Amacker, D Vogel, N Westerfeld, JA Robinson, ...
Human Vaccines 4 (2), 106-114, 2008
142008
ATX-MS-1467 induces long-term tolerance to myelin basic protein in (DR2× Ob1) F1 mice by induction of IL-10-secreting iTregs
ALS De Souza, S Rudin, R Chang, K Mitchell, T Crandall, S Huang, ...
Neurology and Therapy 7, 103-128, 2018
112018
Urinary galectin-3 binding protein (G3BP) as a biomarker for disease activity and renal pathology characteristics in lupus nephritis
H Ding, Y Shen, C Lin, L Qin, S He, M Dai, SL Okitsu, JA DeMartino, ...
Arthritis Research & Therapy 24 (1), 77, 2022
52022
Autoantibody repertoire characterization provides insight into the pathogenesis of monogenic and polygenic autoimmune diseases
T Clarke, P Du, S Kumar, SL Okitsu, M Schuette, Q An, J Zhang, ...
Frontiers in Immunology 14, 1106537, 2023
42023
Urine Galectin-3 binding protein reflects nephritis activity in systemic lupus erythematosus
F Faustini, H Idborg, E Fuzzi, A Larsson, WR Lie, S Pötzsch, SL Okitsu, ...
Lupus 32 (2), 252-262, 2023
22023
O37 M5049, a novel potent and selective inhibitor of toll-like receptors 7 and 8 (TLR 7/8)
B Sherer, AT Bender, A Pereira, S Reissig, P Haselmayer, SL Okitsu, ...
Lupus Science & Medicine 7 (Suppl 1), 2020
22020
Failure of in vitro differentiation of Plasmodium falciparum gametocytes into ookinetes arises because of poor gamete fertilisation
MJ Delves, SR Marques, A Ruecker, U Straschil, C Miguel-Blanco, ...
bioRxiv, 216721, 2017
22017
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