| Targeting protein–protein interactions for therapeutic intervention: a challenge for the future G Zinzalla, DE Thurston Future medicinal chemistry 1 (1), 65-93, 2009 | 328 | 2009 |
| A selective high affinity MYC-binding compound inhibits MYC: MAX interaction and MYC-dependent tumor cell proliferation A Castell, Q Yan, K Fawkner, P Hydbring, F Zhang, V Verschut, M Franco, ... Scientific reports 8 (1), 10064, 2018 | 116 | 2018 |
| Chemical variation of natural product-like scaffolds: design and synthesis of spiroketal derivatives G Zinzalla, LG Milroy, SV Ley Organic & Biomolecular Chemistry 4 (10), 1977-2002, 2006 | 97 | 2006 |
| Observation of unphosphorylated STAT3 core protein binding to target dsDNA by PEMSA and X-ray crystallography E Nkansah, R Shah, GW Collie, GN Parkinson, J Palmer, KM Rahman, ... FEBS letters 587 (7), 833-839, 2013 | 89 | 2013 |
| Synthesis of chiral chromium tricarbonyl labeled thymine PNA monomers via the Ugi reaction C Baldoli, S Maiorana, E Licandro, G Zinzalla, D Perdicchia Organic Letters 4 (24), 4341-4344, 2002 | 84 | 2002 |
| Small-molecule inhibition of c-MYC: MAX leucine zipper formation is revealed by ion mobility mass spectrometry SR Harvey, M Porrini, C Stachl, D MacMillan, G Zinzalla, PE Barran Journal of the American Chemical Society 134 (47), 19384-19392, 2012 | 67 | 2012 |
| Chemical variation of natural-product-like scaffolds: design, synthesis, and biological activity of fused bicyclic acetal derivatives LG Milroy, G Zinzalla, G Prencipe, P Michel, SV Ley, M Gunaratnam, ... Angewandte Chemie-International Edition 46 (14), 2493-2496, 2007 | 60 | 2007 |
| Investigation of the protein alkylation sites of the STAT3: STAT3 inhibitor Stattic by mass spectrometry S Heidelberger, G Zinzalla, D Antonow, S Essex, BP Basu, J Palmer, ... Bioorganic & medicinal chemistry letters 23 (16), 4719-4722, 2013 | 59 | 2013 |
| Crystal structures and nuclear magnetic resonance studies of the apo form of the c-MYC: MAX bHLHZip complex reveal a helical basic region in the absence of DNA S Sammak, N Hamdani, F Gorrec, MD Allen, SMV Freund, M Bycroft, ... Biochemistry 58 (29), 3144-3154, 2019 | 58 | 2019 |
| The SWI/SNF subunit INI1 contains an N-terminal winged helix DNA binding domain that is a target for mutations in schwannomatosis MD Allen, SMV Freund, G Zinzalla, M Bycroft Structure 23 (7), 1344-1349, 2015 | 50 | 2015 |
| Natural‐Product‐Like Spiroketals and Fused Bicyclic Acetals as Potential Therapeutic Agents for B‐Cell Chronic Lymphocytic Leukaemia LG Milroy, G Zinzalla, F Loiseau, Z Qian, G Prencipe, C Pepper, C Fegan, ... ChemMedChem: Chemistry Enabling Drug Discovery 3 (12), 1922-1935, 2008 | 48 | 2008 |
| A new ferrocene conjugate of a tyrosine PNA monomer: synthesis and electrochemical properties C Baldoli, L Falciola, E Licandro, S Maiorana, P Mussini, P Ramani, ... Journal of organometallic chemistry 689 (25), 4791-4802, 2004 | 43 | 2004 |
| Targeting protein–protein interactions (PPIs) of transcription factors: challenges of intrinsically disordered proteins (IDPs) and regions (IDRs) S Sammak, G Zinzalla Progress in biophysics and molecular biology 119 (1), 41-46, 2015 | 38 | 2015 |
| Molecular dynamics studies of the STAT3 homodimer: DNA complex: relationships between STAT3 mutations and protein–DNA recognition J Husby, AK Todd, SM Haider, G Zinzalla, DE Thurston, S Neidle Journal of chemical information and modeling 52 (5), 1179-1192, 2012 | 34 | 2012 |
| Facile nucleophilic substitution at the C3a tertiary carbon of the 3a-bromohexahydropyrrolo [2, 3-b] indole scaffold I Villanueva-Margalef, DE Thurston, G Zinzalla Organic & Biomolecular Chemistry 8 (23), 5294-5303, 2010 | 32 | 2010 |
| The structure of INI 1/hSNF 5 RPT 1 and its interactions with the c‐MYC: MAX heterodimer provide insights into the interplay between MYC and the SWI/SNF chromatin remodeling … S Sammak, MD Allen, N Hamdani, M Bycroft, G Zinzalla The FEBS journal 285 (22), 4165-4180, 2018 | 26 | 2018 |
| A novel small-molecule inhibitor of IL-6 signalling G Zinzalla, MR Haque, BP Basu, J Anderson, SL Kaye, S Haider, F Hasan, ... Bioorganic & medicinal chemistry letters 20 (23), 7029-7032, 2010 | 26 | 2010 |
| Facile oxidation of electron-poor benzo [b] thiophenes to the corresponding sulfones with an aqueous solution of H 2 O 2 and P 2 O 5 D Antonow, T Marrafa, I Dawood, T Ahmed, MR Haque, DE Thurston, ... Chemical communications 46 (13), 2289-2291, 2010 | 26 | 2010 |
| A new way forward in cancer drug discovery: inhibiting the SWI/SNF chromatin remodelling complex G Zinzalla Chembiochem 17 (8), 677-682, 2016 | 25 | 2016 |
| Structure of the BRK domain of the SWI/SNF chromatin remodeling complex subunit BRG1 reveals a potential role in protein–protein interactions MD Allen, M Bycroft, G Zinzalla Protein Science 29 (4), 1033-1039, 2020 | 23 | 2020 |
