Leo Heijnen
Leo Heijnen
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Presence of SARS-Coronavirus-2 RNA in sewage and correlation with reported COVID-19 prevalence in the early stage of the epidemic in the Netherlands
G Medema, L Heijnen, G Elsinga, R Italiaander, A Brouwer
Environmental Science & Technology Letters 7 (7), 511-516, 2020
Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana
K Mayer, C Schüller, R Wambutt, G Murphy, G Volckaert, T Pohl, ...
Nature 402 (6763), 769-777, 1999
The tomato Mi-1 gene confers resistance to both root-knot nematodes and potato aphids
T Jesse, J Wijbrandi, L Heinen, R Hogers, A Frijters, J Groenendijk, ...
Nature biotechnology 16 (13), 1365-1369, 1998
Implementation of environmental surveillance for SARS-CoV-2 virus to support public health decisions: Opportunities and challenges
G Medema, F Been, L Heijnen, S Petterson
Current opinion in environmental science & health 17, 49-71, 2020
Quantitative detection of E. coli, E. coli O157 and other shiga toxin producing E. coli in water samples using a culture method combined with real-time PCR
L Heijnen, G Medema
Journal of Water and Health 4 (4), 487-498, 2006
Monitoring SARS-CoV-2 circulation and diversity through community wastewater sequencing, the Netherlands and Belgium
R Izquierdo-Lara, G Elsinga, L Heijnen, BBO Munnink, ...
Emerging infectious diseases 27 (5), 1405, 2021
Direct comparison of selected methods for genetic categorisation of Cryptosporidium parvum and Cryptosporidium hominis species
RM Chalmers, C Ferguson, S Cacciò, RB Gasser, YGA El-Osta, L Heijnen, ...
International Journal for Parasitology 35 (4), 397-410, 2005
Intracellular transport of recombinant coronavirus spike proteins: implications for virus assembly
H Vennema, L Heijnen, A Zijderveld, MC Horzinek, WJ Spaan
Journal of virology 64 (1), 339-346, 1990
Escherichia coli O157: H7 in drinking water from private water supplies in the Netherlands
FM Schets, M During, R Italiaander, L Heijnen, SA Rutjes, ...
Water research 39 (18), 4485-4493, 2005
Mutational analysis of the murine coronavirus spike protein: effect on cell-to-cell fusion
Virology 214 (2), 453-463, 1995
Surveillance of influenza A and the pandemic influenza A (H1N1) 2009 in sewage and surface water in the Netherlands
L Heijnen, G Medema
Journal of water and health 9 (3), 434-442, 2011
Droplet digital RT-PCR to detect SARS-CoV-2 signature mutations of variants of concern in wastewater
L Heijnen, G Elsinga, M de Graaf, R Molenkamp, MPG Koopmans, ...
Science of The Total Environment 799, 149456, 2021
Homologous RNA recombination allows efficient introduction of site-specific mutations into the genome of coronavirus MHV-A59 via synthetic co-replicating RNAs
RG van der Most, L Heijnen, WJM Spaan, RJ de Groot
Nucleic acids research 20 (13), 3375-3381, 1992
Method for generating oligonucleotides, in particular for the detection of amplified restriction fragments obtained using AFLP®
MJT Van Eijk, RCJ Hogers, L Heijnen
US Patent 7,166,429, 2007
Method for rapid detection of viable Escherichia coli in water using real-time NASBA
L Heijnen, G Medema
Water research 43 (12), 3124-3132, 2009
Enhancement of the vaccinia virus/phage T7 RNA polymerase expression system using encephalomyocarditis virus 5'-untranslated region sequences
H Vennema, R Rijnbrand, L Heijnen, MC Horzinek, WJM Spaan
Gene 108 (2), 201-209, 1991
A novel glycoprotein of feline infectious peritonitis coronavirus contains a KDEL-like endoplasmic reticulum retention signal
H Vennema, L Heijnen, PJ Rottier, MC Horzinek, WJ Spaan
Journal of virology 66 (8), 4951-4956, 1992
Evidence for an ancient chromosomal duplication in Arabidopsis thaliana by sequencing and analyzing a 400‐kb contig at the APETALA2 locus on chromosome 4 1
N Terryn, L Heijnen, A De Keyser, M Van Asseldonck, R De Clercq, ...
FEBS letters 445 (2-3), 237-245, 1999
Prevalence and circulation patterns of SARS-CoV-2 variants in European sewage mirror clinical data of 54 European cities
S Agrawal, L Orschler, S Schubert, K Zachmann, L Heijnen, S Tavazzi, ...
Water Research 214, 118162, 2022
Biosynthesis and function of the coronavirus spike protein
H Vennema, PJM Rottier, L Heijnen, GJ Godeke, MC Horzinek, ...
Coronaviruses and their Diseases, 9-19, 1990
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Artikelen 1–20