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Aleix Prat
Aleix Prat
Hospital Clinic
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Comprehensive molecular portraits of human breast tumours
Brigham & Women’s Hospital & Harvard Medical School Chin Lynda 9 11 Park ...
Nature 490 (7418), 61-70, 2012
109552012
Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer
A Prat, JS Parker, O Karginova, C Fan, C Livasy, JI Herschkowitz, X He, ...
Breast cancer research 12, 1-18, 2010
27652010
Deconstructing the molecular portraits of breast cancer
A Prat, CM Perou
Molecular oncology 5 (1), 5-23, 2011
18172011
Olaparib tablets as maintenance therapy in patients with platinum-sensitive, relapsed ovarian cancer and a BRCA1/2 mutation (SOLO2/ENGOT-Ov21): a double-blind, randomised …
E Pujade-Lauraine, JA Ledermann, F Selle, V Gebski, RT Penson, ...
The lancet oncology 18 (9), 1274-1284, 2017
16382017
4th ESO–ESMO international consensus guidelines for advanced breast cancer (ABC 4)
F Cardoso, E Senkus, A Costa, E Papadopoulos, M Aapro, F André, ...
Annals of Oncology 29 (8), 1634-1657, 2018
12182018
Clinical implications of the intrinsic molecular subtypes of breast cancer
A Prat, E Pineda, B Adamo, P Galván, A Fernández, L Gaba, M Díez, ...
The Breast 24, S26-S35, 2015
11382015
Prognostic significance of progesterone receptor–positive tumor cells within immunohistochemically defined luminal A breast cancer
A Prat, MCU Cheang, M Martín, JS Parker, E Carrasco, R Caballero, ...
Journal of clinical oncology 31 (2), 203, 2013
7302013
Molecular characterization of basal‐like and non‐basal‐like triple‐negative breast cancer
A Prat, B Adamo, MCU Cheang, CK Anders, LA Carey, CM Perou
The oncologist 18 (2), 123-133, 2013
7122013
Endocrine-therapy-resistant ESR1 variants revealed by genomic characterization of breast-cancer-derived xenografts
S Li, D Shen, J Shao, R Crowder, W Liu, A Prat, X He, S Liu, J Hoog, C Lu, ...
Cell reports 4 (6), 1116-1130, 2013
6742013
Randomized phase II neoadjuvant comparison between letrozole, anastrozole, and exemestane for postmenopausal women with estrogen receptor–rich stage 2 to 3 breast cancer …
MJ Ellis, VJ Suman, J Hoog, L Lin, J Snider, A Prat, JS Parker, J Luo, ...
Journal of clinical oncology 29 (17), 2342, 2011
6472011
PI3K inhibition impairs BRCA1/2 expression and sensitizes BRCA-proficient triple-negative breast cancer to PARP inhibition
YH Ibrahim, C García-García, V Serra, L He, K Torres-Lockhart, A Prat, ...
Cancer discovery 2 (11), 1036-1047, 2012
5902012
A renewable tissue resource of phenotypically stable, biologically and ethnically diverse, patient-derived human breast cancer xenograft models
X Zhang, S Claerhout, A Prat, LE Dobrolecki, I Petrovic, Q Lai, MD Landis, ...
Cancer research 73 (15), 4885-4897, 2013
4972013
USP15 stabilizes TGF-β receptor I and promotes oncogenesis through the activation of TGF-β signaling in glioblastoma
PJA Eichhorn, L Rodón, A Gonzŕlez-Juncŕ, A Dirac, M Gili, ...
Nature medicine 18 (3), 429-435, 2012
4192012
PAM50 breast cancer subtyping by RT-qPCR and concordance with standard clinical molecular markers
RRL Bastien, Á Rodríguez-Lescure, MTW Ebbert, A Prat, B Munárriz, ...
BMC medical genomics 5, 1-12, 2012
3932012
Genomic aberrations in the FGFR pathway: opportunities for targeted therapies in solid tumors
R Dienstmann, J Rodon, A Prat, J Perez-Garcia, B Adamo, E Felip, ...
Annals of oncology 25 (3), 552-563, 2014
3912014
Immune-related gene expression profiling after PD-1 blockade in non–small cell lung carcinoma, head and neck squamous cell carcinoma, and melanoma
A Prat, A Navarro, L Paré, N Reguart, P Galván, T Pascual, A Martínez, ...
Cancer research 77 (13), 3540-3550, 2017
3822017
Cyclin E amplification/overexpression is a mechanism of trastuzumab resistance in HER2+ breast cancer patients
M Scaltriti, PJ Eichhorn, J Cortés, L Prudkin, C Aura, J Jiménez, ...
Proceedings of the National Academy of Sciences 108 (9), 3761-3766, 2011
3692011
PI3K inhibition results in enhanced estrogen receptor function and dependence in hormone receptor–positive breast cancer
A Bosch, Z Li, A Bergamaschi, H Ellis, E Toska, A Prat, JJ Tao, DE Spratt, ...
Science translational medicine 7 (283), 283ra51-283ra51, 2015
3392015
How many etiological subtypes of breast cancer: two, three, four, or more?
WF Anderson, PS Rosenberg, A Prat, CM Perou, ME Sherman
Journal of the National Cancer Institute 106 (8), dju165, 2014
3372014
HER2-enriched subtype as a predictor of pathological complete response following trastuzumab and lapatinib without chemotherapy in early-stage HER2-positive breast cancer …
A Llombart-Cussac, J Cortés, L Paré, P Galván, B Bermejo, N Martínez, ...
The lancet oncology 18 (4), 545-554, 2017
3202017
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