Irene Orlow
Irene Orlow
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The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53
J Pomerantz, N Schreiber-Agus, NJ Liégeois, A Silverman, L Alland, ...
Cell 92 (6), 713-723, 1998
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer
SE Bojesen, KA Pooley, SE Johnatty, J Beesley, K Michailidou, JP Tyrer, ...
Nature genetics 45 (4), 371-384, 2013
Activation of the sphingomyelin signaling pathway in intact EL4 cells and in a cell-free system by IL-1 beta
S Mathias, A Younes, CC Kan, I Orlow, C Joseph, RN Kolesnick
Science 259 (5094), 519-522, 1993
GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer
PDP Pharoah, YY Tsai, SJ Ramus, CM Phelan, EL Goode, K Lawrenson, ...
Nature genetics 45 (4), 362-370, 2013
Lifetime risk of melanoma in CDKN2A mutation carriers in a population-based sample
CB Begg, I Orlow, AJ Hummer, BK Armstrong, A Kricker, LD Marrett, ...
Journal of the National Cancer Institute 97 (20), 1507-1515, 2005
Identification of six new susceptibility loci for invasive epithelial ovarian cancer
KB Kuchenbaecker, SJ Ramus, J Tyrer, A Lee, HC Shen, J Beesley, ...
Nature genetics 47 (2), 164-171, 2015
Deletion of the p16 and p15 genes in human bladder tumors
I Orlow, L Lacombe, GJ Hannon, M Serrano, I Pellicer, G Dalbagni, ...
JNCI: Journal of the National Cancer Institute 87 (20), 1524-1529, 1995
Altered patterns of MDM2 and TP53 expression in human bladder cancer
P Lianes, I Orlow, ZF Zhang, MR Oliva, AS Sarkis, VE Reuter, ...
JNCI: Journal of the National Cancer Institute 86 (17), 1325-1330, 1994
Tumor-infiltrating lymphocyte grade in primary melanomas is independently associated with melanoma-specific survival in the population-based genes, environment and melanoma study
NE Thomas, KJ Busam, L From, A Kricker, BK Armstrong, H Anton-Culver, ...
Journal of Clinical Oncology 31 (33), 4252, 2013
Chromosome 9 allelic losses and microsatellite alterations in human bladder tumors
I Orlow, P Lianes, L Lacombe, G Dalbagni, VE Reuter, C Cordon-Cardo
Cancer Research 54 (11), 2848-2851, 1994
Common variation at 2p13. 3, 3q29, 7p13 and 17q25. 1 associated with susceptibility to pancreatic cancer
EJ Childs, E Mocci, D Campa, PM Bracci, S Gallinger, M Goggins, D Li, ...
Nature genetics 47 (8), 911-916, 2015
Deletions of the INK4A gene occur in malignant peripheral nerve sheath tumors but not in neurofibromas
HP Kourea, I Orlow, BW Scheithauer, C Cordon-Cardo, JM Woodruff
The American journal of pathology 155 (6), 1855-1860, 1999
Genetic evidence in melanoma and bladder cancers that p16 and p53 function in separate pathways of tumor suppression
NA Gruis, J Weaver-Feldhaus, Q Liu, C Frye, R Eeles, I Orlow, L Lacombe, ...
The American journal of pathology 146 (5), 1199, 1995
Previous lung diseases and lung cancer risk: a pooled analysis from the International Lung Cancer Consortium
DR Brenner, P Boffetta, EJ Duell, H Bickeböller, A Rosenberger, ...
American journal of epidemiology 176 (7), 573-585, 2012
Deletions of the INK4A gene in superficial bladder tumors: association with recurrence
I Orlow, H LaRue, I Osman, L Lacombe, L Moore, F Rabbani, F Meyer, ...
The American journal of pathology 155 (1), 105-113, 1999
PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS
MC Southey, DE Goldgar, R Winqvist, K Pylkäs, F Couch, M Tischkowitz, ...
Journal of medical genetics 53 (12), 800-811, 2016
Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer
H Shen, BL Fridley, H Song, K Lawrenson, JM Cunningham, SJ Ramus, ...
Nature communications 4 (1), 1-10, 2013
Cannabis smoking and lung cancer risk: Pooled analysis in the I nternational L ung C ancer C onsortium
LR Zhang, H Morgenstern, S Greenland, SC Chang, P Lazarus, MD Teare, ...
International journal of cancer 136 (4), 894-903, 2015
Genomic and mutational profiling to assess clonal relationships between multiple non–small cell lung cancers
N Girard, I Ostrovnaya, C Lau, B Park, M Ladanyi, D Finley, C Deshpande, ...
Clinical cancer research 15 (16), 5184-5190, 2009
Presence of human papilloma virus in tumor tissue from children with retinoblastoma: an alternative mechanism for tumor development
M Orjuela, VP Castaneda, C Ridaura, E Lecona, C Leal, DH Abramson, ...
Clinical cancer research 6 (10), 4010-4016, 2000
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