| The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53 J Pomerantz, N Schreiber-Agus, NJ Liégeois, A Silverman, L Alland, ... Cell 92 (6), 713-723, 1998 | 2013 | 1998 |
| Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer SE Bojesen, KA Pooley, SE Johnatty, J Beesley, K Michailidou, JP Tyrer, ... Nature genetics 45 (4), 371-384, 2013 | 646 | 2013 |
| Activation of the sphingomyelin signaling pathway in intact EL4 cells and in a cell-free system by IL-1β S Mathias, A Younes, CC Kan, I Orlow, C Joseph, RN Kolesnick Science 259 (5094), 519-522, 1993 | 523 | 1993 |
| GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer PDP Pharoah, YY Tsai, SJ Ramus, CM Phelan, EL Goode, K Lawrenson, ... Nature genetics 45 (4), 362-370, 2013 | 416 | 2013 |
| Identification of six new susceptibility loci for invasive epithelial ovarian cancer KB Kuchenbaecker, SJ Ramus, J Tyrer, A Lee, HC Shen, J Beesley, ... Nature genetics 47 (2), 164-171, 2015 | 307 | 2015 |
| Tumor-infiltrating lymphocyte grade in primary melanomas is independently associated with melanoma-specific survival in the population-based genes, environment and melanoma study NE Thomas, KJ Busam, L From, A Kricker, BK Armstrong, H Anton-Culver, ... Journal of Clinical Oncology 31 (33), 4252, 2013 | 301 | 2013 |
| Lifetime risk of melanoma in CDKN2A mutation carriers in a population-based sample CB Begg, I Orlow, AJ Hummer, BK Armstrong, A Kricker, LD Marrett, ... Journal of the National Cancer Institute 97 (20), 1507-1515, 2005 | 273 | 2005 |
| Previous lung diseases and lung cancer risk: a pooled analysis from the International Lung Cancer Consortium DR Brenner, P Boffetta, EJ Duell, H Bickeboeller, A Rosenberger, ... American journal of epidemiology 176 (7), 573-585, 2012 | 263 | 2012 |
| Altered patterns of MDM2 and TP53 expression in human bladder cancer P Lianes, I Orlow, ZF Zhang, MR Oliva, AS Sarkis, VE Reuter, ... JNCI: Journal of the National Cancer Institute 86 (17), 1325-1330, 1994 | 262 | 1994 |
| Common variation at 2p13. 3, 3q29, 7p13 and 17q25. 1 associated with susceptibility to pancreatic cancer EJ Childs, E Mocci, D Campa, PM Bracci, S Gallinger, M Goggins, D Li, ... Nature genetics 47 (8), 911-916, 2015 | 257 | 2015 |
| Deletion of the p16 and p15 genes in human bladder tumors I Orlow, L Lacombe, GJ Hannon, M Serrano, I Pellicer, G Dalbagni, ... JNCI: Journal of the National Cancer Institute 87 (20), 1524-1529, 1995 | 244 | 1995 |
| PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS MC Southey, DE Goldgar, R Winqvist, K Pylkäs, F Couch, M Tischkowitz, ... Journal of medical genetics 53 (12), 800-811, 2016 | 238 | 2016 |
| Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer AP Klein, BM Wolpin, HA Risch, RZ Stolzenberg-Solomon, E Mocci, ... Nature communications 9 (1), 556, 2018 | 224 | 2018 |
| Increased risk of lung cancer in individuals with a family history of the disease: a pooled analysis from the International Lung Cancer Consortium ML Coté, M Liu, S Bonassi, M Neri, AG Schwartz, DC Christiani, MR Spitz, ... European journal of cancer 48 (13), 1957-1968, 2012 | 221 | 2012 |
| Chromosome 9 allelic losses and microsatellite alterations in human bladder tumors I Orlow, P Lianes, L Lacombe, G Dalbagni, VE Reuter, C Cordon-Cardo Cancer Research 54 (11), 2848-2851, 1994 | 209 | 1994 |
| Cannabis smoking and lung cancer risk: Pooled analysis in the I nternational L ung C ancer C onsortium LR Zhang, H Morgenstern, S Greenland, SC Chang, P Lazarus, MD Teare, ... International journal of cancer 136 (4), 894-903, 2015 | 202 | 2015 |
| Identification of nine new susceptibility loci for endometrial cancer TA O’mara, DM Glubb, F Amant, D Annibali, K Ashton, J Attia, PL Auer, ... Nature communications 9 (1), 3166, 2018 | 201 | 2018 |
| Deletions of the INK4A gene occur in malignant peripheral nerve sheath tumors but not in neurofibromas HP Kourea, I Orlow, BW Scheithauer, C Cordon-Cardo, JM Woodruff The American journal of pathology 155 (6), 1855-1860, 1999 | 199 | 1999 |
| Association between NRAS and BRAF mutational status and melanoma-specific survival among patients with higher-risk primary melanoma NE Thomas, SN Edmiston, A Alexander, PA Groben, E Parrish, A Kricker, ... JAMA oncology 1 (3), 359-368, 2015 | 195 | 2015 |
| Genomic and mutational profiling to assess clonal relationships between multiple non–small cell lung cancers N Girard, I Ostrovnaya, C Lau, B Park, M Ladanyi, D Finley, C Deshpande, ... Clinical cancer research 15 (16), 5184-5190, 2009 | 180 | 2009 |
