Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification F Liu, P Lössl, R Scheltema, R Viner, AJR Heck Nature communications 8 (1), 15473, 2017 | 286 | 2017 |
The diverse and expanding role of mass spectrometry in structural and molecular biology P Lössl, M van de Waterbeemd, AJR Heck The EMBO journal 35 (24), 2634-2657, 2016 | 249 | 2016 |
The interactome of intact mitochondria by cross-linking mass spectrometry provides evidence for coexisting respiratory supercomplexes F Liu, P Lössl, BM Rabbitts, RS Balaban, AJR Heck Molecular & Cellular Proteomics 17 (2), 216-232, 2018 | 171 | 2018 |
Boundaries of mass resolution in native mass spectrometry P Lössl, J Snijder, AJR Heck Journal of the American Society for Mass Spectrometry 25 (6), 906-917, 2014 | 162 | 2014 |
Benchmarking multiple fragmentation methods on an orbitrap fusion for top-down phospho-proteoform characterization AM Brunner, P Lössl, F Liu, R Huguet, C Mullen, M Yamashita, ... Analytical chemistry 87 (8), 4152-4158, 2015 | 132 | 2015 |
Structures of the cyanobacterial circadian oscillator frozen in a fully assembled state J Snijder, JM Schuller, A Wiegard, P Lössl, N Schmelling, IM Axmann, ... Science 355 (6330), 1181-1184, 2017 | 128 | 2017 |
Structural basis for inhibition of TLR2 by staphylococcal superantigen-like protein 3 (SSL3) KJ Koymans, LJ Feitsma, THC Brondijk, PC Aerts, E Lukkien, P Lössl, ... Proceedings of the National Academy of Sciences 112 (35), 11018-11023, 2015 | 114 | 2015 |
Analysis of nidogen-1/laminin γ1 interaction by cross-linking, mass spectrometry, and computational modeling reveals multiple binding modes P Lössl, K Kölbel, D Tänzler, D Nannemann, CH Ihling, MV Keller, ... PLoS One 9 (11), e112886, 2014 | 62 | 2014 |
Lysine conjugation properties in human IgGs studied by integrating high‐resolution native mass spectrometry and bottom‐up proteomics V Gautier, AJ Boumeester, P Lössl, AJR Heck Proteomics 15 (16), 2756-2765, 2015 | 56 | 2015 |
Low pH-induced conformational change and dimerization of sortilin triggers endocytosed ligand release N Leloup, P Lössl, DH Meijer, M Brennich, AJR Heck, DME Thies-Weesie, ... Nature Communications 8 (1), 1708, 2017 | 54 | 2017 |
Nucleotide‐dependent conformational changes of the AAA+ ATPase p97 revisited JM Schuller, F Beck, P Lössl, AJR Heck, F Förster FEBS letters 590 (5), 595-604, 2016 | 48 | 2016 |
Deciphering the interplay among multisite phosphorylation, interaction dynamics, and conformational transitions in a tripartite protein system P Lössl, AM Brunner, F Liu, AC Leney, M Yamashita, RA Scheltema, ... ACS central science 2 (7), 445-455, 2016 | 34 | 2016 |
CysK2 from Mycobacterium tuberculosis Is an O-Phospho-l-Serine-Dependent S-Sulfocysteine Synthase EM Steiner, D Böth, P Lössl, F Vilaplana, R Schnell, G Schneider Journal of bacteriology 196 (19), 3410-3420, 2014 | 33 | 2014 |
Simultaneous assessment of kinetic, site‐specific, and structural aspects of enzymatic protein phosphorylation M van de Waterbeemd, P Lössl, V Gautier, F Marino, M Yamashita, ... Angewandte Chemie International Edition 53 (36), 9660-9664, 2014 | 26 | 2014 |
Combining amine-reactive cross-linkers and photoreactive amino acids for 3D-structure analysis of proteins and protein complexes P Lössl, A Sinz Meth Mol Biol 1394 (Proteomics in Systems Biology), 109-127, 2015 | 24 | 2015 |
Recombinant expression of the full-length ectodomain of LDL receptor-related protein 1 (LRP1) unravels pH-dependent conformational changes and the stoichiometry of binding with … C De Nardis, P Lössl, M Van Den Biggelaar, PK Madoori, N Leloup, ... Journal of Biological Chemistry 292 (3), 912-924, 2017 | 23 | 2017 |
Quantifying positional isomers (QPI) by top-down mass spectrometry AM Brunner, P Lössl, PP Geurink, H Ovaa, P Albanese, AFM Altelaar, ... Molecular & Cellular Proteomics 20, 2021 | 4 | 2021 |
A novel hybrid high speed mass spectrometer allows rapid translation from biomarker candidates to targeted clinical tests using 15N labeled proteins M Wahle, PM Remes, V Albrecht, J Mueller-Reif, S Steigerwald, ... bioRxiv, 2024.06. 02.597029, 2024 | 2 | 2024 |
A highly charged topic P Lössl Nature Physics 16 (3), 368-368, 2020 | 2 | 2020 |
Charting the COSMICs P Lössl Nature Chemical Biology 17 (12), 1212-1212, 2021 | | 2021 |