BAGEL3: automated identification of genes encoding bacteriocins and (non-) bactericidal posttranslationally modified peptides AJ Van Heel, A de Jong, M Montalban-Lopez, J Kok, OP Kuipers Nucleic acids research 41 (W1), W448-W453, 2013 | 464 | 2013 |
BAGEL4: a user-friendly web server to thoroughly mine RiPPs and bacteriocins AJ van Heel, A de Jong, C Song, JH Viel, J Kok, OP Kuipers Nucleic acids research 46 (W1), W278-W281, 2018 | 312 | 2018 |
New developments in RiPP discovery, enzymology and engineering M Montalbán-López, TA Scott, S Ramesh, IR Rahman, AJ Van Heel, ... Natural product reports 38 (1), 130-239, 2021 | 177 | 2021 |
Evaluating the feasibility of lantibiotics as an alternative therapy against bacterial infections in humans AJ van Heel, M Montalban-Lopez, OP Kuipers Expert opinion on drug metabolism & toxicology 7 (6), 675-680, 2011 | 120 | 2011 |
Designing and producing modified, new-to-nature peptides with antimicrobial activity by use of a combination of various lantibiotic modification enzymes AJ van Heel, D Mu, M Montalbán-López, D Hendriks, OP Kuipers ACS synthetic biology 2 (7), 397-404, 2013 | 86 | 2013 |
Potentiating the activity of nisin against Escherichia coli L Zhou, AJ Van Heel, M Montalban-Lopez, OP Kuipers Frontiers in cell and developmental biology 4, 7, 2016 | 59 | 2016 |
Employing the promiscuity of lantibiotic biosynthetic machineries to produce novel antimicrobials M Montalbán-López, AJ van Heel, OP Kuipers FEMS Microbiology Reviews 41 (1), 5-18, 2017 | 47 | 2017 |
The length of a lantibiotic hinge region has profound influence on antimicrobial activity and host specificity L Zhou, AJ van Heel, OP Kuipers Frontiers in microbiology, 11, 2015 | 47 | 2015 |
Increasing the success rate of lantibiotic drug discovery by synthetic biology M Montalbán-López, L Zhou, A Buivydas, AJ van Heel, OP Kuipers Expert opinion on drug discovery 7 (8), 695-709, 2012 | 40 | 2012 |
Specificity and application of the lantibiotic protease NisP M Montalbán-López, J Deng, AJ Van Heel, OP Kuipers Frontiers in microbiology 9, 160, 2018 | 36 | 2018 |
Protein surface and core dynamics show concerted hydration‐dependent activation K Wood, FX Gallat, R Otten, AJ van Heel, M Lethier, L van Eijck, M Moulin, ... Angewandte Chemie International Edition 52 (2), 665-668, 2013 | 36 | 2013 |
Incorporation of tryptophan analogues into the lantibiotic nisin L Zhou, J Shao, Q Li, AJ van Heel, MP de Vries, J Broos, OP Kuipers Amino Acids 48 (5), 1309-1318, 2016 | 35 | 2016 |
Genome-guided identification of novel head-to-tail cyclized antimicrobial peptides, exemplified by the discovery of pumilarin AJ van Heel, M Montalban-Lopez, Q Oliveau, OP Kuipers Microbial genomics 3 (10), 2017 | 28 | 2017 |
Cell surface engineering of Bacillus subtilis improves production yields of heterologously expressed α-amylases H Cao, AJ van Heel, H Ahmed, M Mols, OP Kuipers Microbial Cell Factories 16 (1), 1-9, 2017 | 22 | 2017 |
MiniBacillus PG10 as a Convenient and Effective Production Host for Lantibiotics AY van Tilburg, AJ van Heel, J Stülke, NAW de Kok, AS Rueff, ... ACS synthetic biology 9 (7), 1833-1842, 2020 | 17 | 2020 |
Bacillus subtilis Biosensor Engineered To Assess Meat Spoilage A Daszczuk, Y Dessalegne, I Drenth, E Hendriks, E Jo, T van Lente, ... ACS synthetic biology 3 (12), 999-1002, 2014 | 14 | 2014 |
Draft genome sequences of seven thermophilic spore-forming bacteria isolated from foods that produce highly heat-resistant spores, comprising Geobacillus spp., Caldibacillus … EM Berendsen, MHJ Wells-Bennik, AO Krawczyk, A de Jong, A van Heel, ... Genome Announcements 4 (3), e00105-16, 2016 | 13 | 2016 |
Identification of essential amino acid residues in the nisin dehydratase NisB R Khusainov, AJ van Heel, J Lubelski, GN Moll, OP Kuipers Frontiers in microbiology 6, 102, 2015 | 12 | 2015 |
Draft Genome Sequences of 10 Bacillus subtilis Strains That Form Spores with High or Low Heat Resistance EM Berendsen, MHJ Wells-Bennik, AO Krawczyk, A de Jong, A van Heel, ... Genome announcements 4 (2), e00124-16, 2016 | 11 | 2016 |
Recombinant pediocin in Lactococcus lactis: increased production by propeptide fusion and improved potency by co‐production with PedC A Back, F Borges, C Mangavel, C Paris, E Rondags, R Kapel, A Aymes, ... Microbial Biotechnology 9 (4), 466-477, 2016 | 10 | 2016 |