Jeroen Pouwels
Jeroen Pouwels
Helsinki University Faculty of Medicine
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Integrin inactivators: balancing cellular functions in vitro and in vivo
D Bouvard, J Pouwels, N De Franceschi, J Ivaska
Nature reviews Molecular cell biology 14 (7), 430-442, 2013
SHARPIN is an endogenous inhibitor of β1-integrin activation
JK Rantala, J Pouwels, T Pellinen, S Veltel, P Laasola, E Mattila, ...
Nature cell biology 13 (11), 1315-1324, 2011
SHANK proteins limit integrin activation by directly interacting with Rap1 and R-Ras
J Lilja, T Zacharchenko, M Georgiadou, G Jacquemet, N De Franceschi, ...
Nature cell biology 19 (4), 292-305, 2017
Comparative structural analysis and substrate specificity engineering of the hyperthermostable β-glucosidase CelB from Pyrococcus furiosus
T Kaper, JHG Lebbink, J Pouwels, J Kopp, GE Schulz, J van der Oost, ...
Biochemistry 39 (17), 4963-4970, 2000
The cytoskeleton and the secretory pathway are not involved in targeting the cowpea mosaic virus movement protein to the cell periphery
J Pouwels, GNM Van Der Krogt, J Van Lent, T Bisseling, J Wellink
Virology 297 (1), 48-56, 2002
Shugoshin 1 plays a central role in kinetochore assembly and is required for kinetochore targeting of Plk1
J Pouwels, AM Kukkonen, W Lan, JR Daum, GJ Gorbsky, PT Stukenberg, ...
Cell cycle 6 (13), 1579-1585, 2007
Formin-like 2 promotes β1-integrin trafficking and invasive motility downstream of PKCα
Y Wang, A Arjonen, J Pouwels, H Ta, P Pausch, G Bange, U Engel, X Pan, ...
Developmental cell 34 (4), 475-483, 2015
Selective integrin endocytosis is driven by interactions between the integrin α-chain and AP2
N De Franceschi, A Arjonen, N Elkhatib, K Denessiouk, AG Wrobel, ...
Nature structural & molecular biology 23 (2), 172-179, 2016
SHARPIN regulates uropod detachment in migrating lymphocytes
J Pouwels, N De Franceschi, P Rantakari, K Auvinen, M Karikoski, ...
Cell reports 5 (3), 619-628, 2013
Negative regulators of integrin activity
J Pouwels, J Nevo, T Pellinen, J Ylänne, J Ivaska
Journal of cell science 125 (14), 3271-3280, 2012
Studies on the origin and structure of tubules made by the movement protein of Cowpea mosaic virus
J Pouwels, T Van Der Velden, J Willemse, JW Borst, J Van Lent, ...
Journal of general virology 85 (12), 3787-3796, 2004
Dietary flavonoid fisetin induces a forced exit from mitosis by targeting the mitotic spindle checkpoint
AL Salmela, J Pouwels, A Varis, AM Kukkonen, P Toivonen, PK Halonen, ...
Carcinogenesis 30 (6), 1032-1040, 2009
Cowpea mosaic virus: effects on host cell processes
J Pouwels, JE Carette, J Van Lent, J Wellink
Molecular plant pathology 3 (6), 411-418, 2002
Activity and stability of hyperthermophilic enzymes: a comparative study on two archaeal β-glycosidases
J Pouwels, M Moracci, B Cobucci-Ponzano, G Perugino, J van der Oost, ...
Extremophiles 4 (3), 157-164, 2000
Identification of distinct steps during tubule formation by the movement protein of Cowpea mosaic virus
J Pouwels, N Kornet, N van Bers, T Guighelaar, J van Lent, T Bisseling, ...
Journal of general virology 84 (12), 3485-3494, 2003
Loss of p38γ MAPK induces pleiotropic mitotic defects and massive cell death
A Kukkonen-Macchi, O Sicora, K Kaczynska, C Oetken-Lindholm, ...
Journal of cell science 124 (2), 216-227, 2011
The Movement Protein of Cowpea Mosaic Virus Binds GTP and Single-Stranded Nucleic Acid In Vitro
CM Carvalho, J Pouwels, JWM Van Lent, T Bisseling, RW Goldbach, ...
Journal of virology 78 (3), 1591-1594, 2004
Perturbation of Incenp function impedes anaphase chromatid movements and chromosomal passenger protein flux at centromeres
LJ Ahonen, AM Kukkonen, J Pouwels, MA Bolton, CD Jingle, ...
Chromosoma 118 (1), 71-84, 2009
Mutually exclusive roles of SHARPIN in integrin inactivation and NF-κB signaling
N De Franceschi, E Peuhu, M Parsons, S Rissanen, I Vattulainen, ...
PloS one 10 (11), e0143423, 2015
The flavonoid eupatorin inactivates the mitotic checkpoint leading to polyploidy and apoptosis
AL Salmela, J Pouwels, A Kukkonen-Macchi, S Waris, P Toivonen, ...
Experimental cell research 318 (5), 578-592, 2012
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