Indoleamides are active against drug-resistant Mycobacterium tuberculosis S Lun, H Guo, OK Onajole, M Pieroni, H Gunosewoyo, G Chen, ... Nature communications 4 (1), 2907, 2013 | 152 | 2013 |
Preliminary structure–activity relationships and biological evaluation of novel antitubercular indolecarboxamide derivatives against drug-susceptible and drug-resistant … OK Onajole, M Pieroni, SK Tipparaju, S Lun, J Stec, G Chen, ... Journal of medicinal chemistry 56 (10), 4093-4103, 2013 | 146 | 2013 |
The First CNS-Active Carborane: A Novel P2X7 Receptor Antagonist with Antidepressant Activity SM Wilkinson, H Gunosewoyo, ML Barron, A Boucher, M McDonnell, ... ACS chemical neuroscience 5 (5), 335-339, 2014 | 131 | 2014 |
P2X purinergic receptor ligands: recently patented compounds H Gunosewoyo, M Kassiou Expert opinion on therapeutic patents 20 (5), 625-646, 2010 | 101 | 2010 |
Identification of Novel Coumestan Derivatives as Polyketide Synthase 13 Inhibitors against Mycobacterium tuberculosis W Zhang, S Lun, SH Wang, XW Jiang, F Yang, J Tang, AL Manson, ... Journal of medicinal chemistry 61 (3), 791-803, 2018 | 69 | 2018 |
Inhibition of GSK-3 induces differentiation and impaired glucose metabolism in renal cancer K Pal, Y Cao, IN Gaisina, S Bhattacharya, SK Dutta, E Wang, ... Molecular cancer therapeutics 13 (2), 285-296, 2014 | 65 | 2014 |
Therapeutic inducers of apoptosis in ovarian cancer M Binju, MA Amaya-Padilla, G Wan, H Gunosewoyo, Y Suryo Rahmanto, ... Cancers 11 (11), 1786, 2019 | 59 | 2019 |
Molecular probes for P2X7 receptor studies H Gunosewoyo, MJ Coster, M Kassiou Current medicinal chemistry 14 (14), 1505-1523, 2007 | 59 | 2007 |
Tuberculosis: pathogenesis, current treatment regimens and new drug targets SSR Alsayed, H Gunosewoyo International journal of molecular sciences 24 (6), 5202, 2023 | 49 | 2023 |
Characterization of maleimide-based glycogen synthase kinase-3 (GSK-3) inhibitors as stimulators of steroidogenesis H Gunosewoyo, A Midzak, IN Gaisina, EV Sabath, A Fedolak, T Hanania, ... Journal of medicinal chemistry 56 (12), 5115-5129, 2013 | 48 | 2013 |
Cubyl amides: Novel P2X7 receptor antagonists H Gunosewoyo, JL Guo, MR Bennett, MJ Coster, M Kassiou Bioorganic & medicinal chemistry letters 18 (13), 3720-3723, 2008 | 44 | 2008 |
Optimization of 2-phenylcyclopropylmethylamines as selective serotonin 2C receptor agonists and their evaluation as potential antipsychotic agents J Cheng, PM Giguère, OK Onajole, W Lv, A Gaisin, H Gunosewoyo, ... Journal of medicinal chemistry 58 (4), 1992-2002, 2015 | 43 | 2015 |
Evaluation of protein kinase inhibitors with PLK4 cross-over potential in a pre-clinical model of cancer A Suri, AW Bailey, MT Tavares, H Gunosewoyo, CP Dyer, ... International journal of molecular sciences 20 (9), 2112, 2019 | 37 | 2019 |
Amidoalkylindoles as potent and selective cannabinoid type 2 receptor agonists with in vivo efficacy in a mouse model of multiple sclerosis Y Shi, YH Duan, YY Ji, ZL Wang, YR Wu, H Gunosewoyo, XY Xie, ... Journal of medicinal chemistry 60 (16), 7067-7083, 2017 | 36 | 2017 |
Combination treatment with the GSK-3 inhibitor 9-ING-41 and CCNU cures orthotopic chemoresistant glioblastoma in patient-derived xenograft models A Ugolkov, W Qiang, G Bondarenko, D Procissi, I Gaisina, CD James, ... Translational oncology 10 (4), 669-678, 2017 | 36 | 2017 |
Identification of a Glycogen Synthase Kinase‐3β Inhibitor that Attenuates Hyperactivity in CLOCK Mutant Mice AP Kozikowski, H Gunosewoyo, S Guo, IN Gaisina, RL Walter, ... ChemMedChem 6 (9), 1593-1602, 2011 | 35 | 2011 |
Identification of Novel Coumestan Derivatives as Polyketide Synthase 13 Inhibitors against Mycobacterium tuberculosis. Part II W Zhang, S Lun, LL Liu, S Xiao, G Duan, H Gunosewoyo, F Yang, J Tang, ... Journal of medicinal chemistry 62 (7), 3575-3589, 2019 | 32 | 2019 |
Design, synthesis, and biological evaluation of novel arylcarboxamide derivatives as anti-tubercular agents SSR Alsayed, S Lun, G Luna, CC Beh, AD Payne, N Foster, WR Bishai, ... RSC advances 10 (13), 7523-7540, 2020 | 31 | 2020 |
Kinase targets in CNS drug discovery H Gunosewoyo, L Yu, L Munoz, M Kassiou Future Medicinal Chemistry 9 (3), 303-314, 2017 | 29 | 2017 |
Tying up tranylcypromine: Novel selective histone lysine specific demethylase 1 (LSD1) inhibitors YY Ji, SD Lin, YJ Wang, MB Su, W Zhang, H Gunosewoyo, F Yang, J Li, ... European Journal of Medicinal Chemistry 141, 101-112, 2017 | 27 | 2017 |