Alexandra (Sasha) Zhernakova
Alexandra (Sasha) Zhernakova
Professor of Human Genome and Exposome, University Medical Centre Groningen, The Netherlands
Geverifieerd e-mailadres voor umcg.nl - Homepage
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Genetics of rheumatoid arthritis contributes to biology and drug discovery
Y Okada, D Wu, G Trynka, T Raj, C Terao, K Ikari, Y Kochi, K Ohmura, ...
Nature 506 (7488), 376-381, 2014
17632014
Systematic identification of trans eQTLs as putative drivers of known disease associations
HJ Westra, MJ Peters, T Esko, H Yaghootkar, C Schurmann, J Kettunen, ...
Nature genetics 45 (10), 1238-1243, 2013
15702013
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci
EA Stahl, S Raychaudhuri, EF Remmers, G Xie, S Eyre, BP Thomson, Y Li, ...
Nature genetics 42 (6), 508-514, 2010
13452010
Population-level analysis of gut microbiome variation
G Falony, M Joossens, S Vieira-Silva, J Wang, Y Darzi, K Faust, ...
Science 352 (6285), 560-564, 2016
12672016
Environment dominates over host genetics in shaping human gut microbiota
D Rothschild, O Weissbrod, E Barkan, A Kurilshikov, T Korem, D Zeevi, ...
Nature 555 (7695), 210-215, 2018
12152018
Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity
A Zhernakova, A Kurilshikov, MJ Bonder, EF Tigchelaar, M Schirmer, ...
Science 352 (6285), 565-569, 2016
10862016
Multiple common variants for celiac disease influencing immune gene expression
PCA Dubois, G Trynka, L Franke, KA Hunt, J Romanos, A Curtotti, ...
Nature genetics 42 (4), 295-302, 2010
10042010
Newly identified genetic risk variants for celiac disease related to the immune response
KA Hunt, A Zhernakova, G Turner, GAR Heap, L Franke, M Bruinenberg, ...
Nature genetics 40 (4), 395-402, 2008
7592008
Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease
G Trynka, KA Hunt, NA Bockett, J Romanos, V Mistry, A Szperl, SF Bakker, ...
Nature genetics 43 (12), 1193-1201, 2011
7582011
A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21
DA Van Heel, L Franke, KA Hunt, R Gwilliam, A Zhernakova, M Inouye, ...
Nature genetics 39 (7), 827-829, 2007
7572007
The neuroactive potential of the human gut microbiota in quality of life and depression
M Valles-Colomer, G Falony, Y Darzi, EF Tigchelaar, J Wang, RY Tito, ...
Nature microbiology 4 (4), 623-632, 2019
6972019
Proton pump inhibitors affect the gut microbiome
F Imhann, MJ Bonder, AV Vila, J Fu, Z Mujagic, L Vork, EF Tigchelaar, ...
Gut 65 (5), 740-748, 2016
6472016
High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis
S Eyre, J Bowes, D Diogo, A Lee, A Barton, P Martin, A Zhernakova, ...
Nature genetics 44 (12), 1336-1340, 2012
6092012
Detecting shared pathogenesis from the shared genetics of immune-related diseases
A Zhernakova, CC Van Diemen, C Wijmenga
Nature Reviews Genetics 10 (1), 43-55, 2009
5852009
Linking the human gut microbiome to inflammatory cytokine production capacity
M Schirmer, SP Smeekens, H Vlamakis, M Jaeger, M Oosting, ...
Cell 167 (4), 1125-1136. e8, 2016
5592016
Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity
S Wahl, A Drong, B Lehne, M Loh, WR Scott, S Kunze, PC Tsai, JS Ried, ...
Nature 541 (7635), 81-86, 2017
5572017
The effect of host genetics on the gut microbiome
MJ Bonder, A Kurilshikov, EF Tigchelaar, Z Mujagic, F Imhann, AV Vila, ...
Nature genetics 48 (11), 1407-1412, 2016
4702016
Gut microbiome structure and metabolic activity in inflammatory bowel disease
EA Franzosa, A Sirota-Madi, J Avila-Pacheco, N Fornelos, HJ Haiser, ...
Nature microbiology 4 (2), 293-305, 2019
4582019
The gut microbiome contributes to a substantial proportion of the variation in blood lipids
J Fu, MJ Bonder, MC Cenit, EF Tigchelaar, A Maatman, JAM Dekens, ...
Circulation research 117 (9), 817-824, 2015
4242015
Interplay of host genetics and gut microbiota underlying the onset and clinical presentation of inflammatory bowel disease
F Imhann, AV Vila, MJ Bonder, J Fu, D Gevers, MC Visschedijk, ...
Gut 67 (1), 108-119, 2018
4182018
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Artikelen 1–20