Disruption of the mouse mTOR gene leads to early postimplantation lethality and prohibits embryonic stem cell development YG Gangloff, M Mueller, SG Dann, P Svoboda, M Sticker, JF Spetz, ... Molecular and cellular biology 24 (21), 9508-9516, 2004 | 606 | 2004 |
The metabolic checkpoint kinase mTOR is essential for IL-15 signaling during the development and activation of NK cells A Marçais, J Cherfils-Vicini, C Viant, S Degouve, S Viel, A Fenis, ... Nature immunology 15 (8), 749-757, 2014 | 565 | 2014 |
Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy V Risson, L Mazelin, M Roceri, H Sanchez, V Moncollin, C Corneloup, ... Journal of Cell Biology 187 (6), 859-874, 2009 | 408 | 2009 |
The histone fold is a key structural motif of transcription factor TFIID YG Gangloff, C Romier, S Thuault, S Werten, I Davidson Trends in biochemical sciences 26 (4), 250-257, 2001 | 171 | 2001 |
Arrest of myelination and reduced axon growth when Schwann cells lack mTOR DL Sherman, M Krols, LMN Wu, M Grove, KA Nave, YG Gangloff, ... Journal of Neuroscience 32 (5), 1817-1825, 2012 | 161 | 2012 |
The Human TFIID Components TAFII135 and TAFII20 and the Yeast SAGA Components ADA1 and TAFII68 Heterodimerize to Form Histone-Like Pairs YG Gangloff, S Werten, C Romier, L Carré, O Poch, D Moras, I Davidson Molecular and cellular biology 20 (1), 340-351, 2000 | 132 | 2000 |
Resistance exercise initiates mechanistic target of rapamycin (mTOR) translocation and protein complex co-localisation in human skeletal muscle Z Song, DR Moore, N Hodson, C Ward, JR Dent, MF O’Leary, AM Shaw, ... Scientific reports 7 (1), 5028, 2017 | 116 | 2017 |
Histone folds mediate selective heterodimerization of yeast TAFII25 with TFIID components yTAFII47 and yTAFII65 and with SAGA component ySPT7 YG Gangloff, SL Sanders, C Romier, D Kirschner, PA Weil, L Tora, ... Molecular and cellular biology, 2001 | 90 | 2001 |
Dissecting the interaction network of multiprotein complexes by pairwise coexpression of subunits in E. coli S Fribourg, C Romier, S Werten, YG Gangloff, A Poterszman, D Moras Journal of molecular biology 306 (2), 363-373, 2001 | 89 | 2001 |
The TFIID Components Human TAFII140 andDrosophila BIP2 (TAFII155) Are Novel Metazoan Homologues of Yeast TAFII47 Containing a Histone Fold and a … YG Gangloff, JC Pointud, S Thuault, L Carré, C Romier, S Muratoglu, ... Molecular and cellular biology 21 (15), 5109-5121, 2001 | 86 | 2001 |
Crystal structure of a subcomplex of human transcription factor TFIID formed by TATA binding protein-associated factors hTAF4 (hTAFII135) and hTAF12 (hTAFII20) S Werten, A Mitschler, C Romier, YG Gangloff, S Thuault, I Davidson, ... Journal of Biological Chemistry 277 (47), 45502-45509, 2002 | 74 | 2002 |
Increased Serpina3n release into circulation during glucocorticoid‐mediated muscle atrophy M Gueugneau, D d'Hose, C Barbé, M De Barsy, P Lause, D Maiter, ... Journal of cachexia, sarcopenia and muscle 9 (5), 929-946, 2018 | 61 | 2018 |
mTOR inactivation in myocardium from infant mice rapidly leads to dilated cardiomyopathy due to translation defects and p53/JNK-mediated apoptosis L Mazelin, B Panthu, AS Nicot, E Belotti, L Tintignac, G Teixeira, Q Zhang, ... Journal of molecular and cellular cardiology 97, 213-225, 2016 | 55 | 2016 |
Human TAFII55 Interacts with the Vitamin D3 and Thyroid Hormone Receptors and with Derivatives of the Retinoid X Receptor That Have Altered Transactivation … AC Lavigne, G Mengus, YG Gangloff, JM Wurtz, I Davidson Molecular and Cellular Biology 19 (8), 5486-5494, 1999 | 54 | 1999 |
Myopathy caused by mammalian target of rapamycin complex 1 (mTORC1) inactivation is not reversed by restoring mitochondrial function K Romanino, L Mazelin, V Albert, A Conjard-Duplany, S Lin, ... Proceedings of the National Academy of Sciences 108 (51), 20808-20813, 2011 | 48 | 2011 |
Distinct Mutations in Yeast TAFII25 Differentially Affect the Composition of TFIID and SAGA Complexes as Well as Global Gene Expression Patterns DB Kirschner, E vom Baur, C Thibault, SL Sanders, YG Gangloff, ... Molecular and cellular biology 22 (9), 3178-3193, 2002 | 41 | 2002 |
Functional analysis of the TFIID-specific yeast TAF4 (yTAFII48) reveals an unexpected organization of its histone-fold domain S Thuault, YG Gangloff, J Kirchner, S Sanders, S Werten, C Romier, ... Journal of Biological Chemistry 277 (47), 45510-45517, 2002 | 31 | 2002 |
S6K1 controls pancreatic β cell size independently of intrauterine growth restriction SH Um, M Sticker-Jantscheff, GC Chau, K Vintersten, M Mueller, ... The Journal of clinical investigation 125 (7), 2736-2747, 2015 | 29 | 2015 |
Synergistic Transcriptional Activation by TATA-Binding Protein and hTAFII28 Requires Specific Amino Acids of the hTAFII28 Histone Fold AC Lavigne, YG Gangloff, L Carré, G Mengus, C Birck, O Poch, C Romier, ... Molecular and cellular biology 19 (7), 5050-5060, 1999 | 26 | 1999 |
Lack of muscle mTOR kinase activity causes early onset myopathy and compromises whole‐body homeostasis Q Zhang, A Duplany, V Moncollin, S Mouradian, E Goillot, L Mazelin, ... Journal of cachexia, sarcopenia and muscle 10 (1), 35-53, 2019 | 23 | 2019 |