| Thiazole and thiadiazole analogues as a novel class of adenosine receptor antagonists JE van Muijlwijk-Koezen, H Timmerman, RC Vollinga, ... Journal of medicinal chemistry 44 (5), 749-762, 2001 | 171 | 2001 |
| Isoquinoline and quinazoline urea analogues as antagonists for the human adenosine A3 receptor JE van Muijlwijk-Koezen, H Timmerman, H van der Goot, WM Menge J Med Chem 43 (11), 2227-2238, 0 | 154* | |
| Fragment growing induces conformational changes in acetylcholine-binding protein: a structural and thermodynamic analysis E Edink, P Rucktooa, K Retra, A Akdemir, T Nahar, O Zuiderveld, ... Journal of the American Chemical Society 133 (14), 5363-5371, 2011 | 108 | 2011 |
| Allosteric modulation of A3 adenosine receptors by a series of 3-(2-pyridinyl) isoquinoline derivatives ZG Gao, JE Van Muijlwijk-Koezen, A Chen, CE Müller, AP Ijzerman, ... Molecular Pharmacology 60 (5), 1057-1063, 2001 | 98 | 2001 |
| A novel class of adenosine A3 receptor ligands. 2. Structure affinity profile of a series of isoquinoline and quinazoline compounds JE van Muijlwijk-Koezen, H Timmerman, R Link, H van der Goot, ... Journal of medicinal chemistry 41 (21), 3994-4000, 1998 | 85 | 1998 |
| A novel class of adenosine A3 receptor ligands. 1. 3-(2-Pyridinyl) isoquinoline derivatives JE van Muijlwijk-Koezen, H Timmerman, R Link, H van der Goot, ... Journal of medicinal chemistry 41 (21), 3987-3993, 1998 | 75 | 1998 |
| Activating students’ interest and participation in lectures and practical courses using their electronic devices W Maikel, L van Rens, . and van Muijlwijk-Koezen Jacqueline E. Journal of Chemical Education 91, 1830–1837, 2014 | 66 | 2014 |
| Ligand-, structure- and pharmacophore-based molecular fingerprints: a case study on adenosine A1, A2A, A2B, and A3 receptor antagonists F Sirci, L Goracci, D Rodríguez, J van Muijlwijk-Koezen, ... Journal of computer-aided molecular design 26, 1247-1266, 2012 | 62 | 2012 |
| Fragment library screening reveals remarkable similarities between the G protein-coupled receptor histamine H4 and the ion channel serotonin 5-HT3A MHP Verheij, C de Graaf, GE de Kloe, S Nijmeijer, HF Vischer, RA Smits, ... Bioorganic & medicinal chemistry letters 21 (18), 5460-5464, 2011 | 47 | 2011 |
| Surface plasmon resonance biosensor based fragment screening using acetylcholine binding protein identifies ligand efficiency hot spots (le hot spots) by deconstruction of … GE de Kloe, K Retra, M Geitmann, P Källblad, T Nahar, R van Elk, AB Smit, ... American Chemical Society, 2010 | 47 | 2010 |
| When fragments link: a bibliometric perspective on the development of fragment-based drug discovery AKS Romasanta, P van der Sijde, I Hellsten, RE Hubbard, GM Keseru, ... Drug Discovery Today 23 (9), 1596-1609, 2018 | 45 | 2018 |
| Design, Synthesis, and Structure-Activity Relationships of Highly Potent 5-HT(3) Receptor Ligands MH Verheij, AJ Thompson, JE van Muijlwijk-Koezen, L S.C., R Leurs, ... J. Med. Chem. 55, 8603-8614, 2012 | 44 | 2012 |
| Surface plasmon resonance biosensor analysis as a useful tool in FBDD K Retra, H Irth, JE van Muijlwijk-Koezen Drug Discovery Today: Technologies 7 (3), e181-e187, 2010 | 44 | 2010 |
| Innovation in pharmaceutical R&D: mapping the research landscape AKS Romasanta, P van der Sijde, J van Muijlwijk-Koezen Scientometrics 125, 1801-1832, 2020 | 41 | 2020 |
| Small and colorful stones make beautiful mosaics: fragment-based chemogenomics C de Graaf, HF Vischer, GE de Kloe, AJ Kooistra, S Nijmeijer, M Kuijer, ... Drug Discovery Today 18 (7-8), 323-330, 2013 | 37 | 2013 |
| Synthesis and use of FSCPX, an irreversible adenosine A1 antagonist, as a ‘receptor knock-down’tool JE van Muijlwijk-Koezen, H Timmerman, RP van der Sluis, ... Bioorganic & medicinal chemistry letters 11 (6), 815-818, 2001 | 32 | 2001 |
| Scientific perspectivism in secondary-school chemistry education: Integrating concepts and skills in chemical thinking I Landa, H Westbroek, F Janssen, J van Muijlwijk, M Meeter Science & Education 29, 1361-1388, 2020 | 24 | 2020 |
| Modulation of agonist responses at the A1 adenosine receptor by an irreversible antagonist, receptor–G protein uncoupling and by the G protein activation state A Lorenzen, MW Beukers, PH van der Graaf, H Lang, ... Biochemical pharmacology 64 (8), 1251-1265, 2002 | 24 | 2002 |
| Frijtag von Drabbe Künzel, J.; de Groote, M.; Visser, S.; Ijzerman JE van Muijlwijk-Koezen, H Timmerman, RC Vollinga J. Med. Chem 44 (5), 749-762, 2001 | 19 | 2001 |
| 2 The Adenosine A3 Receptor and its Ligands JE Van Muijlwijk-Koezen, H Timmerman, AP Ijzerman Progress in medicinal chemistry 38, 61-113, 2001 | 19 | 2001 |
