Hao Yu
Hao Yu
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Direct observation of transition paths during the folding of proteins and nucleic acids
K Neupane, DAN Foster, DR Dee, H Yu, F Wang, MT Woodside
Science 352 (6282), 239-242, 2016
Hidden dynamics in the unfolding of individual bacteriorhodopsin proteins
H Yu, MGW Siewny, DT Edwards, AW Sanders, TT Perkins
Science 355 (6328), 945-950, 2017
Experimental validation of free-energy-landscape reconstruction from non-equilibrium single-molecule force spectroscopy measurements
AN Gupta, A Vincent, K Neupane, H Yu, F Wang, MT Woodside
Nature Physics 7 (8), 631-634, 2011
Energy landscape analysis of native folding of the prion protein yields the diffusion constant, transition path time, and rates
H Yu, AN Gupta, X Liu, K Neupane, AM Brigley, I Sosova, MT Woodside
Proceedings of the National Academy of Sciences 109 (36), 14452-14457, 2012
Direct observation of multiple misfolding pathways in a single prion protein molecule
H Yu, X Liu, K Neupane, AN Gupta, AM Brigley, A Solanki, I Sosova, ...
Proceedings of the National Academy of Sciences 109 (14), 5283-5288, 2012
Single-molecule force spectroscopy of the add adenine riboswitch relates folding to regulatory mechanism
K Neupane, H Yu, DAN Foster, F Wang, MT Woodside
Nucleic acids research 39 (17), 7677-7687, 2011
Transition path times for nucleic acid folding determined from energy-landscape analysis of single-molecule trajectories
K Neupane, DB Ritchie, H Yu, DAN Foster, F Wang, MT Woodside
Physical review letters 109 (6), 068102, 2012
Protein misfolding occurs by slow diffusion across multiple barriers in a rough energy landscape
H Yu, DR Dee, X Liu, AM Brigley, I Sosova, MT Woodside
Proceedings of the National Academy of Sciences 112 (27), 8308-8313, 2015
Quantifying the initial unfolding of bacteriorhodopsin reveals retinal stabilization
H Yu, PR Heenan, DT Edwards, L Uyetake, TT Perkins
Angewandte Chemie International Edition 58 (6), 1710-1713, 2019
Single-molecule approaches to prion protein misfolding
H Yu, DR Dee, MT Woodside
Prion 7 (2), 140-146, 2013
Improved free-energy landscape reconstruction of bacteriorhodopsin highlights local variations in unfolding energy
PR Heenan, H Yu, MGW Siewny, TT Perkins
The Journal of chemical physics 148 (12), 123313, 2018
Quantifying the native energetics stabilizing bacteriorhodopsin by single-molecule force spectroscopy
H Yu, DR Jacobson, H Luo, TT Perkins
Physical Review Letters 125 (6), 068102, 2020
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