| Development of an activity-based probe and in silico design reveal highly selective inhibitors for diacylglycerol lipase-α in brain MP Baggelaar, FJ Janssen, ACM van Esbroeck, H den Dulk, M Allarà, ... Angew Chem Int Ed Engl 52 (46), 12081-12085, 2013 | 108 | 2013 |
| Highly selective, reversible inhibitor identified by comparative chemoproteomics modulates diacylglycerol lipase activity in neurons MP Baggelaar, PJP Chameau, V Kantae, J Hummel, KL Hsu, F Janssen, ... Journal of the American Chemical Society 137 (27), 8851-8857, 2015 | 92 | 2015 |
| Discovery of Glycine Sulfonamides as Dual Inhibitors of sn-1-Diacylglycerol Lipase α and α/β-Hydrolase Domain 6 FJ Janssen, H Deng, MP Baggelaar, M Allarà, T van der Wel, H den Dulk, ... Journal of Medicinal Chemistry 57 (15), 6610-6622, 2014 | 45 | 2014 |
| Triazole ureas act as diacylglycerol lipase inhibitors and prevent fasting-induced refeeding H Deng, S Kooijman, AMCH van den Nieuwendijk, D Ogasawara, ... Journal of Medicinal Chemistry 60 (1), 428-440, 2017 | 44 | 2017 |
| A natural substrate-based fluorescence assay for inhibitor screening on diacylglycerol lipase α T van Der Wel, FJ Janssen, MP Baggelaar, H Deng, H den Dulk, ... Journal of lipid research 56 (4), 927-935, 2015 | 42 | 2015 |
| Inhibitors of diacylglycerol lipases in neurodegenerative and metabolic disorders FJ Janssen, M van der Stelt Bioorganic & medicinal chemistry letters 26 (16), 3831-3837, 2016 | 41 | 2016 |
| Comprehensive Analysis of Structure–Activity Relationships of α-Ketoheterocycles as sn-1-Diacylglycerol Lipase α Inhibitors FJ Janssen, MP Baggelaar, JJA Hummel, HS Overkleeft, BF Cravatt, ... Journal of medicinal chemistry 58 (24), 9742-9753, 2015 | 24 | 2015 |
| Chiral disubstituted piperidinyl ureas: a class of dual diacylglycerol lipase-α and ABHD6 inhibitors H Deng, T van der Wel, RJ van den Berg, AMCH van den Nieuwendijk, ... MedChemComm 8 (5), 982-988, 2017 | 13 | 2017 |
| Inside Back Cover: Development of an Activity‐Based Probe and In Silico Design Reveal Highly Selective Inhibitors for Diacylglycerol Lipase‐α in Brain (Angew. Chem. Int. Ed. 46 … MP Baggelaar, FJ Janssen, ACM van Esbroeck, H den Dulk, M Allarà, ... Angewandte Chemie International Edition 52 (46), 12193-12193, 2013 | 2* | 2013 |
| Discovery of novel inhibitors to investigate diacylglycerol lipases and α/β hydrolase domain 16A FJ Janssen Leiden University, 2016 | | 2016 |
| Diacylglycerol lipase inhibitors prevent fasting-induced refeeding in mice H Deng, S Kooijman, A van den Nieuwendijk, D Ogasawara, ... Chemical Tools to Modulate Endocannabinoid Biosynthesis, 0 | | |
| Discovery of DH376, a 2, 4-substituted triazole urea, as a potent and selective inhibitor for diacylglycerol lipases H Deng, S Kooijman, A van den Nieuwendijk, D Ogasawara, ... Chemical Tools to Modulate Endocannabinoid Biosynthesis, 0 | | |
