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Margaret Fahnestock
Margaret Fahnestock
Professor of Neuroscience, McMaster University
Geverifieerd e-mailadres voor mcmaster.ca - Homepage
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The anxiolytic effect of Bifidobacterium longum NCC3001 involves vagal pathways for gut–brain communication
P Bercik, AJ Park, D Sinclair, A Khoshdel, J Lu, X Huang, Y Deng, ...
Neurogastroenterology & Motility 23 (12), 1132-1139, 2011
11472011
Kindling and status epilepticus models of epilepsy: rewiring the brain
K Morimoto, M Fahnestock, RJ Racine
Progress in neurobiology 73 (1), 1-60, 2004
11062004
Precursor form of brain‐derived neurotrophic factor and mature brain‐derived neurotrophic factor are decreased in the pre‐clinical stages of Alzheimer's disease
S Peng, J Wuu, EJ Mufson, M Fahnestock
Journal of neurochemistry 93 (6), 1412-1421, 2005
7632005
The precursor pro-nerve growth factor is the predominant form of nerve growth factor in brain and is increased in Alzheimer's disease
M Fahnestock, B Michalski, B Xu, MD Coughlin
Molecular and Cellular Neuroscience 18 (2), 210-220, 2001
6482001
The microglial innate immune receptor TREM2 is required for synapse elimination and normal brain connectivity
F Filipello, R Morini, I Corradini, V Zerbi, A Canzi, B Michalski, M Erreni, ...
Immunity 48 (5), 979-991. e8, 2018
5092018
The valproic acid-induced rodent model of autism
C Nicolini, M Fahnestock
Experimental neurology 299, 217-227, 2018
4462018
Quantitation of BDNF mRNA in human parietal cortex by competitive reverse transcription-polymerase chain reaction: decreased levels in Alzheimer's disease
RMD Holsinger, J Schnarr, P Henry, VT Castelo, M Fahnestock
Molecular Brain Research 76 (2), 347-354, 2000
4122000
Pro-brain-derived neurotrophic factor is decreased in parietal cortex in Alzheimer’s disease
B Michalski, M Fahnestock
Molecular Brain Research 111 (1-2), 148-154, 2003
3362003
Increased proNGF levels in subjects with mild cognitive impairment and mild Alzheimer disease
S Peng, J Wuu, EJ Mufson, M Fahnestock
Journal of Neuropathology & Experimental Neurology 63 (6), 641-649, 2004
2972004
Performance of heterozygous brain-derived neurotrophic factor knockout mice on behavioral analogues of anxiety, nociception, and depression.
GM MacQueen, K Ramakrishman, SD Croll, JA Siuciak, G Yu, T Young, ...
Behavioral neuroscience 115 (5), 1145, 2001
2562001
Decreased brain-derived neurotrophic factor depends on amyloid aggregation state in transgenic mouse models of Alzheimer's disease
S Peng, DJ Garzon, M Marchese, W Klein, SD Ginsberg, BM Francis, ...
Journal of Neuroscience 29 (29), 9321-9329, 2009
2452009
Oligomeric amyloid decreases basal levels of brain-derived neurotrophic factor (BDNF) mRNA via specific downregulation of BDNF transcripts IV and V in differentiated human …
DJ Garzon, M Fahnestock
Journal of Neuroscience 27 (10), 2628-2635, 2007
2302007
The nerve growth factor precursor proNGF exhibits neurotrophic activity but is less active than mature nerve growth factor
M Fahnestock, G Yu, B Michalski, S Mathew, A Colquhoun, GM Ross, ...
Journal of neurochemistry 89 (3), 581-592, 2004
2282004
Intraventricular administration of antibodies to nerve growth factor retards kindling and blocks mossy fiber sprouting in adult rats
CE Van der Zee, K Rashid, K Le, KA Moore, J Stanisz, J Diamond, ...
Journal of Neuroscience 15 (7), 5316-5323, 1995
2071995
Neurotrophic factors and Alzheimer’s disease: are we focusing on the wrong molecule?
M Fahnestock, D Garzon, RMD Holsinger, B Michalski
Ageing and Dementia Current and Future Concepts, 241-252, 2002
1882002
A new brain‐derived neurotrophic factor transcript and decrease inbrain‐derived neurotrophic factor transcripts 1, 2 and 3 in Alzheimer's disease parietal cortex
D Garzon, G Yu, M Fahnestock
Journal of neurochemistry 82 (5), 1058-1064, 2002
1712002
Biological activity of nerve growth factor precursor is dependent upon relative levels of its receptors
R Masoudi, MS Ioannou, MD Coughlin, P Pagadala, KE Neet, O Clewes, ...
Journal of biological chemistry 284 (27), 18424-18433, 2009
1642009
ProNGF: a neurotrophic or an apoptotic molecule?
M Fahnestock, G Yu, MD Coughlin
Progress in brain research 146, 101-110, 2004
1642004
Nerve growth factor accelerates seizure development, enhances mossy fiber sprouting, and attenuates seizure-induced decreases in neuronal density in the kindling model of epilepsy
B Adams, M Sazgar, P Osehobo, CEEM Van der Zee, J Diamond, ...
Journal of Neuroscience 17 (14), 5288-5296, 1997
1581997
Differential gene expression profiling of short and long term denervated muscle
J Batt, J Bain, J Goncalves, B Michalski, P Plant, M Fahnestock, ...
The FASEB Journal 20 (1), 115-117, 2006
1492006
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