| Isomerization and oxidation of vitamin a in cone-dominant retinas: a novel pathway for visual-pigment regeneration in daylight NL Mata, RA Radu, RS Clemmons, GH Travis Neuron 36 (1), 69-80, 2002 | 454 | 2002 |
| Reductions in serum vitamin A arrest accumulation of toxic retinal fluorophores: a potential therapy for treatment of lipofuscin-based retinal diseases RA Radu, Y Han, TV Bui, S Nusinowitz, D Bok, J Lichter, K Widder, ... Investigative ophthalmology & visual science 46 (12), 4393-4401, 2005 | 305 | 2005 |
| Treatment with isotretinoin inhibits lipofuscin accumulation in a mouse model of recessive Stargardt's macular degeneration RA Radu, NL Mata, S Nusinowitz, X Liu, PA Sieving, GH Travis Proceedings of the National Academy of Sciences 100 (8), 4742-4747, 2003 | 292 | 2003 |
| Light exposure stimulates formation of A2E oxiranes in a mouse model of Stargardt's macular degeneration RA Radu, NL Mata, A Bagla, GH Travis Proceedings of the National Academy of Sciences 101 (16), 5928-5933, 2004 | 207 | 2004 |
| Accelerated accumulation of lipofuscin pigments in the RPE of a mouse model for ABCA4-mediated retinal dystrophies following Vitamin A supplementation RA Radu, Q Yuan, J Hu, JH Peng, M Lloyd, S Nusinowitz, D Bok, ... Investigative ophthalmology & visual science 49 (9), 3821-3829, 2008 | 193 | 2008 |
| Complement system dysregulation and inflammation in the retinal pigment epithelium of a mouse model for Stargardt macular degeneration RA Radu, J Hu, Q Yuan, DL Welch, J Makshanoff, M Lloyd, S McMullen, ... Journal of Biological Chemistry 286 (21), 18593-18601, 2011 | 168 | 2011 |
| Rpe65 is a retinyl ester binding protein that presents insoluble substrate to the isomerase in retinal pigment epithelial cells NL Mata, WN Moghrabi, JS Lee, TV Bui, RA Radu, J Horwitz, GH Travis Journal of Biological Chemistry 279 (1), 635-643, 2004 | 160 | 2004 |
| Flow of energy in the outer retina in darkness and in light JD Linton, LC Holzhausen, N Babai, H Song, KJ Miyagishima, ... Proceedings of the National Academy of Sciences 107 (19), 8599-8604, 2010 | 130 | 2010 |
| Expression of ABCA4 in the retinal pigment epithelium and its implications for Stargardt macular degeneration TL Lenis, J Hu, SY Ng, Z Jiang, S Sarfare, MB Lloyd, NJ Esposito, ... Proceedings of the National Academy of Sciences 115 (47), E11120-E11127, 2018 | 121 | 2018 |
| Fundus autofluorescence in the Abca4−/− mouse model of Stargardt disease—correlation with accumulation of A2E, retinal function, and histology PC Issa, AR Barnard, MS Singh, E Carter, Z Jiang, RA Radu, ... Investigative ophthalmology & visual science 54 (8), 5602-5612, 2013 | 121 | 2013 |
| Retinoid content, visual responses, and ocular morphology are compromised in the retinas of mice lacking the retinol-binding protein receptor, STRA6 A Ruiz, M Mark, H Jacobs, M Klopfenstein, J Hu, M Lloyd, S Habib, ... Investigative ophthalmology & visual science 53 (6), 3027-3039, 2012 | 115 | 2012 |
| The role of interphotoreceptor retinoid-binding protein on the translocation of visual retinoids and function of cone photoreceptors M Jin, S Li, S Nusinowitz, M Lloyd, J Hu, RA Radu, D Bok, GH Travis Journal of Neuroscience 29 (5), 1486-1495, 2009 | 114 | 2009 |
| Enhanced accumulation of A2E in individuals homozygous or heterozygous for mutations in BEST1 (VMD2) B Bakall, RA Radu, JB Stanton, JM Burke, BS McKay, C Wadelius, ... Experimental eye research 85 (1), 34-43, 2007 | 111 | 2007 |
| Cholesterol-mediated activation of acid sphingomyelinase disrupts autophagy in the retinal pigment epithelium KA Toops, LX Tan, Z Jiang, RA Radu, A Lakkaraju Molecular biology of the cell 26 (1), 1-14, 2015 | 93 | 2015 |
| Retinal pigment epithelium-retinal G protein receptor-opsin mediates light-dependent translocation of all-trans-retinyl esters for synthesis of visual chromophore in retinal … RA Radu, J Hu, J Peng, D Bok, NL Mata, GH Travis Journal of biological chemistry 283 (28), 19730-19738, 2008 | 91 | 2008 |
| Light-driven regeneration of cone visual pigments through a mechanism involving RGR opsin in Müller glial cells A Morshedian, JJ Kaylor, SY Ng, A Tsan, R Frederiksen, T Xu, L Yuan, ... Neuron 102 (6), 1172-1183. e5, 2019 | 90 | 2019 |
| Chicken Retinas Contain a Retinoid Isomerase Activity that Catalyzes the Direct Conversion of all-trans-Retinol to 11-cis-Retinol NL Mata, A Ruiz, RA Radu, TV Bui, GH Travis Biochemistry 44 (35), 11715-11721, 2005 | 90 | 2005 |
| An AAV Dual Vector Strategy Ameliorates the Stargardt Phenotype in Adult Abca4−/− Mice ME McClements, AR Barnard, MS Singh, P Charbel Issa, Z Jiang, ... Human gene therapy 30 (5), 590-600, 2019 | 81 | 2019 |
| The Usher 1B protein, MYO7A, is required for normal localization and function of the visual retinoid cycle enzyme, RPE65 VS Lopes, D Gibbs, RT Libby, TS Aleman, DL Welch, C Lillo, ... Human molecular genetics 20 (13), 2560-2570, 2011 | 73 | 2011 |
| Characterization of native retinal fluorophores involved in biosynthesis of A2E and lipofuscin-associated retinopathies TV Bui, Y Han, RA Radu, GH Travis, NL Mata Journal of Biological Chemistry 281 (26), 18112-18119, 2006 | 71 | 2006 |
