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Joep Beumer
Joep Beumer
Hubrecht Institute, Postdoc Clevers group
Verified email at hubrecht.eu
Title
Cited by
Cited by
Year
SARS-CoV-2 productively infects human gut enterocytes
MM Lamers, J Beumer, J van der Vaart, K Knoops, J Puschhof, ...
Science 369 (6499), 50-54, 2020
17072020
Mutational signature in colorectal cancer caused by genotoxic pks+E. coli
C Pleguezuelos-Manzano, J Puschhof, A Rosendahl Huber, A van Hoeck, ...
Nature 580 (7802), 269-273, 2020
7002020
Cell fate specification and differentiation in the adult mammalian intestine
J Beumer, H Clevers
Nature reviews Molecular cell biology 22 (1), 39-53, 2021
3802021
Induced quiescence of Lgr5+ stem cells in intestinal organoids enables differentiation of hormone-producing enteroendocrine cells
O Basak, J Beumer, K Wiebrands, H Seno, A van Oudenaarden, ...
Cell stem cell 20 (2), 177-190. e4, 2017
3162017
Regulation and plasticity of intestinal stem cells during homeostasis and regeneration
J Beumer, H Clevers
Development 143 (20), 3639-3649, 2016
3022016
Identification of enteroendocrine regulators by real-time single-cell differentiation mapping
H Gehart, JH van Es, K Hamer, J Beumer, K Kretzschmar, JF Dekkers, ...
Cell 176 (5), 1158-1173. e16, 2019
2562019
Enteroendocrine cells switch hormone expression along the crypt-to-villus BMP signalling gradient
J Beumer, B Artegiani, Y Post, F Reimann, F Gribble, TN Nguyen, H Zeng, ...
Nature cell biology 20 (8), 909-916, 2018
2252018
An organoid‐derived bronchioalveolar model for SARS‐CoV‐2 infection of human alveolar type II‐like cells
MM Lamers, J van Der Vaart, K Knoops, S Riesebosch, TI Breugem, ...
The EMBO journal 40 (5), e105912, 2021
1892021
Fast and efficient generation of knock-in human organoids using homology-independent CRISPR–Cas9 precision genome editing
B Artegiani, D Hendriks, J Beumer, R Kok, X Zheng, I Joore, ...
Nature cell biology 22 (3), 321-331, 2020
1882020
Mapping early fate determination in Lgr5+ crypt stem cells using a novel Ki67‐RFP allele
O Basak, M van de Born, J Korving, J Beumer, S van der Elst, JH van Es, ...
The EMBO journal 33 (18), 2057-2068, 2014
1712014
High-resolution mRNA and secretome atlas of human enteroendocrine cells
J Beumer, J Puschhof, J Bauzá-Martinez, A Martínez-Silgado, ...
Cell 181 (6), 1291-1306. e19, 2020
1382020
Intestinal organoid cocultures with microbes
J Puschhof, C Pleguezuelos-Manzano, A Martinez-Silgado, N Akkerman, ...
Nature protocols 16 (10), 4633-4649, 2021
1272021
Establishment and culture of human intestinal organoids derived from adult stem cells
C Pleguezuelos‐Manzano, J Puschhof, S van den Brink, V Geurts, ...
Current protocols in immunology 130 (1), e106, 2020
1072020
Snake venom gland organoids
Y Post, J Puschhof, J Beumer, HM Kerkkamp, MAG de Bakker, ...
Cell 180 (2), 233-247. e21, 2020
1012020
Sequencing metabolically labeled transcripts in single cells reveals mRNA turnover strategies
N Battich, J Beumer, B De Barbanson, L Krenning, CS Baron, ...
Science 367 (6482), 1151-1156, 2020
992020
A CRISPR/Cas9 genetically engineered organoid biobank reveals essential host factors for coronaviruses
J Beumer, MH Geurts, MM Lamers, J Puschhof, J Zhang, J van der Vaart, ...
Nature communications 12 (1), 5498, 2021
662021
Translation and replication dynamics of single RNA viruses
S Boersma, HH Rabouw, LJM Bruurs, T Pavlovič, ALW van Vliet, ...
Cell 183 (7), 1930-1945. e23, 2020
572020
BMP gradient along the intestinal villus axis controls zonated enterocyte and goblet cell states
J Beumer, J Puschhof, FY Yengej, L Zhao, A Martinez-Silgado, ...
Cell Reports 38 (9), 2022
542022
Chuva de Sousa Lopes S, van Zon J, Tans S, Clevers H. Fast and efficient generation of knock-in human organoids using homology-independent CRISPR-Cas9 precision genome editing
B Artegiani, D Hendriks, J Beumer, R Kok, X Zheng, I Joore
Nat. Cell Biol 22, 321-331, 2020
502020
Enteroendocrine dynamics–new tools reveal hormonal plasticity in the gut
J Beumer, H Gehart, H Clevers
Endocrine reviews 41 (5), bnaa018, 2020
452020
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