| Animal versus human oral drug bioavailability: do they correlate? H Musther, A Olivares-Morales, OJD Hatley, B Liu, AR Hodjegan European Journal of Pharmaceutical Sciences 57, 280-291, 2014 | 220 | 2014 |
| Dissolution and Translational Modeling Strategies Toward Establishing an In Vitro-In Vivo Link—a Workshop Summary Report T Heimbach, S Suarez-Sharp, M Kakhi, N Holmstock, A Olivares-Morales, ... The AAPS Journal 21, 1-15, 2019 | 76 | 2019 |
| Use of physiologically based pharmacokinetic (PBPK) modeling for predicting drug-food interactions: an industry perspective AE Riedmaier, K DeMent, J Huckle, P Bransford, C Stillhart, R Lloyd, ... The AAPS journal 22, 1-15, 2020 | 67 | 2020 |
| The use of ROC analysis for the qualitative prediction of human oral bioavailability from animal data A Olivares-Morales, OJD Hatley, D Turner, A Galetin, L Aarons, ... Pharmaceutical research 31, 720-730, 2014 | 35 | 2014 |
| Analysis of the impact of controlled release formulations on oral drug absorption, gut wall metabolism and relative bioavailability of CYP3A substrates using a physiologically … A Olivares-Morales, Y Kamiyama, AS Darwich, L Aarons, ... European Journal of Pharmaceutical Sciences 67, 32-44, 2015 | 33 | 2015 |
| Development of a novel simplified PBPK absorption model to explain the higher relative bioavailability of the OROS® formulation of oxybutynin A Olivares-Morales, A Ghosh, L Aarons, A Rostami-Hodjegan The AAPS journal 18, 1532-1549, 2016 | 30 | 2016 |
| Translating human effective jejunal intestinal permeability to surface-dependent intrinsic permeability: a pragmatic method for a more mechanistic prediction of regional oral … A Olivares-Morales, H Lennernäs, L Aarons, A Rostami-Hodjegan The AAPS journal 17, 1177-1192, 2015 | 29 | 2015 |
| Impact of target interactions on small-molecule drug disposition: an overlooked area RAB van Waterschoot, NJ Parrott, A Olivares-Morales, T Lavé, M Rowland, ... Nature reviews Drug discovery 17 (4), 299-299, 2018 | 24 | 2018 |
| Evaluation of the success of high-throughput physiologically based pharmacokinetic (HT-PBPK) modeling predictions to inform early drug discovery D Naga, N Parrott, GF Ecker, A Olivares-Morales Molecular Pharmaceutics 19 (7), 2203-2216, 2022 | 23 | 2022 |
| Global sensitivity analysis of the Rodgers and Rowland model for prediction of tissue: plasma partitioning coefficients: assessment of the key physiological and physicochemical … E Yau, A Olivares-Morales, M Gertz, N Parrott, AS Darwich, L Aarons, ... The AAPS journal 22, 1-13, 2020 | 18 | 2020 |
| Importance of target-mediated drug disposition for small molecules DA Smith, RA Van Waterschoot, NJ Parrott, A Olivares-Morales, T Lavé, ... Drug discovery today 23 (12), 2023-2030, 2018 | 16 | 2018 |
| Pediatric pharmacokinetics and dose predictions: a report of a satellite meeting to the 10th Juvenile Toxicity Symposium BD van Groen, V Pilla Reddy, J Badée, A Olivares‐Morales, TN Johnson, ... Clinical and translational science 14 (1), 29-35, 2021 | 10 | 2021 |
| Can we predict clinical pharmacokinetics of highly lipophilic compounds by integration of machine learning or in vitro data into physiologically based models? A feasibility … N Parrott, N Manevski, A Olivares-Morales Molecular Pharmaceutics 19 (11), 3858-3868, 2022 | 6 | 2022 |
| LipMetE (Lipophilic Metabolism Efficiency) as a Simple Guide for Half-Life and Dosing Regimen Prediction of Oral Drugs G Cecere, L Guasch, AM Olivares-Morales, K Umehara, AF Stepan ACS Medicinal Chemistry Letters 13 (9), 1444-1451, 2022 | 5 | 2022 |
| Real‐World Data and Physiologically‐Based Mechanistic Models for Precision Medicine. K Wang, N Parrott, A Olivares‐Morales, S Dudal, T Singer, T Lavé, ... Clinical Pharmacology & Therapeutics 107 (4), 2020 | 4 | 2020 |
| Investigation of simplified physiologically‐based pharmacokinetic models in rat and human E Yau, A Olivares‐Morales, K Ogungbenro, L Aarons, M Gertz CPT: Pharmacometrics & Systems Pharmacology 12 (3), 333-345, 2023 | 3 | 2023 |
| A “middle‐out approach” for the prediction of human drug disposition from preclinical data using simplified physiologically based pharmacokinetic (PBPK) models E Yau, M Gertz, K Ogungbenro, L Aarons, A Olivares‐Morales CPT: Pharmacometrics & Systems Pharmacology 12 (3), 346-359, 2023 | 3 | 2023 |
| A Machine Learning Framework to Improve Rat Clearance Predictions and Inform Physiologically Based Pharmacokinetic Modeling A Andrews-Morger, M Reutlinger, N Parrott, A Olivares-Morales Molecular Pharmaceutics 20 (10), 5052-5065, 2023 | 1 | 2023 |
| Translating pharmacology models effectively to predict therapeutic benefit S Dudal, C Bissantz, A Caruso, P David-Pierson, W Driessen, E Koller, ... Drug Discovery Today 27 (6), 1604-1621, 2022 | 1 | 2022 |
| SUBSTITUTED BENZO [f][l, 2, 4JTRIAZOL0 [4, 3-a][l, 4JDIAZEPINES AS GABA A GAMMA! POSITIVE ALLOSTERIC MODULATORS G Cecere, L Gobbi, MC Hernandez, F Knoflach, A Koblet, EC O'connor, ... US Patent App. 18/355,538, 2024 | | 2024 |
Amin Rostami-HodjeganProfessor of Systems Pharmacology, University of Manchester, UKGeverifieerd e-mailadres voor manchester.ac.uk
