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brian james
brian james
Director Genomics Core, Sanford Burnham Prebys Medical Discovery Institute
Geverifieerd e-mailadres voor sbpdiscovery.org
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Phase II pilot study of vemurafenib in patients with metastatic BRAF-mutated colorectal cancer
S Kopetz, J Desai, E Chan, JR Hecht, PJ O'Dwyer, D Maru, V Morris, ...
Journal of clinical oncology 33 (34), 4032, 2015
7312015
EGFR modulates microRNA maturation in response to hypoxia through phosphorylation of AGO2
J Shen, W Xia, YB Khotskaya, L Huo, K Nakanishi, SO Lim, Y Du, Y Wang, ...
Nature 497 (7449), 383-387, 2013
4302013
Hypoxia triggers hedgehog-mediated tumor–stromal interactions in pancreatic cancer
TR Spivak-Kroizman, G Hostetter, R Posner, M Aziz, C Hu, MJ Demeure, ...
Cancer research 73 (11), 3235-3247, 2013
2092013
Ets2 mediated tumor suppressive function and met oncogene inhibition in human non–small cell lung cancer
M Kabbout, MM Garcia, J Fujimoto, DD Liu, D Woods, CW Chow, ...
Clinical cancer research 19 (13), 3383-3395, 2013
1652013
Glutamine depletion regulates Slug to promote EMT and metastasis in pancreatic cancer
MV Recouvreux, MR Moldenhauer, KMO Galenkamp, M Jung, B James, ...
Journal of Experimental Medicine 217 (9), 2020
1242020
Identification of thioredoxin-interacting protein 1 as a hypoxia-inducible factor 1α-induced gene in pancreatic cancer
AF Baker, MY Koh, RR Williams, B James, H Wang, WR Tate, A Gallegos, ...
Pancreas 36 (2), 178-186, 2008
702008
Definition of a novel feed-forward mechanism for glycolysis-HIF1α signaling in hypoxic tumors highlights aldolase A as a therapeutic target
G Grandjean, PR de Jong, BP James, MY Koh, R Lemos, J Kingston, ...
Cancer research 76 (14), 4259-4269, 2016
682016
SARS-CoV-2 ORF9c is a membrane-associated protein that suppresses antiviral responses in cells
A Dominguez Andres, Y Feng, AR Campos, J Yin, CC Yang, B James, ...
BioRxiv, 2020.08. 18.256776, 2020
672020
Expression profiling stratifies mesothelioma tumors and signifies deregulation of spindle checkpoint pathway and microtubule network with therapeutic implications
MB Suraokar, MI Nunez, L Diao, CW Chow, D Kim, C Behrens, H Lin, ...
Annals of oncology 25 (6), 1184-1192, 2014
582014
Regulation of S100A8 stability by RNF5 in intestinal epithelial cells determines intestinal inflammation and severity of colitis
YU Fujita, A Khateb, Y Li, R Tinoco, T Zhang, H Bar-Yoseph, MA Tam, ...
Cell reports 24 (12), 3296-3311. e6, 2018
542018
SBI-0640756 attenuates the growth of clinically unresponsive melanomas by disrupting the eIF4F translation initiation complex
Y Feng, AB Pinkerton, L Hulea, T Zhang, MA Davies, S Grotegut, Y Cheli, ...
Cancer research 75 (24), 5211-5218, 2015
412015
Nuclear Localization of the ERK MAP Kinase Mediated by Drosophila αPS2βPS Integrin and Importin-7
BP James, TA Bunch, S Krishnamoorthy, LA Perkins, DL Brower
Molecular biology of the cell 18 (10), 4190-4199, 2007
382007
Absence of HIF1A leads to glycogen accumulation and an inflammatory response that enables pancreatic tumor growth
M Maruggi, FI Layng, R Lemos Jr, G Garcia, BP James, M Sevilla, ...
Cancer research 79 (22), 5839-5848, 2019
252019
Superoxide dismutase is regulated by LAMMER kinase in Drosophila and human cells
BP James, WD Staatz, ST Wilkinson, E Meuillet, G Powis
Free Radical Biology and Medicine 46 (6), 821-827, 2009
212009
IL-6 contributes to metastatic switch via the differentiation of monocytic-dendritic progenitors into prometastatic immune cells
K Magidey-Klein, TJ Cooper, K Kveler, R Normand, T Zhang, M Timaner, ...
Journal for immunotherapy of cancer 9 (6), 2021
202021
Identification and characterization of IMD-0354 as a glutamine carrier protein inhibitor in melanoma
Y Feng, G Pathria, S Heynen-Genel, M Jackson, B James, J Yin, DA Scott, ...
Molecular cancer therapeutics 20 (5), 816-832, 2021
192021
A myelin basic protein fragment induces sexually dimorphic transcriptome signatures of neuropathic pain in mice
AV Chernov, SK Hullugundi, KA Eddinger, J Dolkas, AG Remacle, ...
Journal of Biological Chemistry 295 (31), 10807-10821, 2020
192020
Neural network recognition of signal modulation types
G Hagedorn, B James, C Miller
Proc. ANNIEC, 170-175, 1997
171997
SPANX control of lamin A/C modulates nuclear architecture and promotes melanoma growth
I Lazar, B Fabre, Y Feng, A Khateb, P Turko, JM Martinez Gomez, ...
Molecular Cancer Research 18 (10), 1560-1573, 2020
142020
A transcriptionally inactive ATF2 variant drives melanomagenesis
G Claps, Y Cheli, T Zhang, M Scortegagna, E Lau, H Kim, J Qi, JL Li, ...
Cell reports 15 (9), 1884-1892, 2016
142016
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